Antiprotozoal Activity of Buxus sempervirens and Activity-Guided Isolation of O-tigloylcyclovirobuxeine-B as the Main Constituent Active against Plasmodium falciparum [PDF]
Buxus sempervirens L. (European Box, Buxaceae) has been used in ethnomedicine to treat malaria. In the course of our screening of plant extracts for antiprotozoal activity, a CH2Cl2 extract from leaves of B.
Marcel Kaiser +2 more
exaly +4 more sources
Investigation of the Variability of Alkaloids in Buxus sempervirens L. Using Multivariate Data Analysis of LC/MS Profiles. [PDF]
Buxus sempervirens L. is a common ornamental plant in southern and central Europe, and has been used ethopharmacologically against a wide variety of diseases due to it containing nor-triterpene alkaloids of the nor-cycloartane type.
Szabó LU, Schmidt TJ.
europepmc +2 more sources
Identification of Antiprotozoal Compounds from Buxus sempervirens L. by PLS-Prediction. [PDF]
Various nor-triterpene alkaloids of Buxus (B.) sempervirens L. have shown remarkable in vitro activity against the causative agents of tropical malaria and East African sleeping sickness.
Szabó LU +3 more
europepmc +2 more sources
Hydroalcoholic extract of Buxus sempervirens shows antiproliferative effect on melanoma, colorectal carcinoma and prostate cancer cells by affecting the autophagic flow. [PDF]
Buxus sempervirens (European Box, Buxaceae, boxwood) has been used in folk medicine to treat rheumatism, arthritis, fever, malaria and skin ulceration while, in recent years, interest has grown on possible employment of boxwood extracts in cancer therapy.
Volpe AR, Carmignani M, Cesare P.
europepmc +2 more sources
Acetonic extract of Buxus sempervirens induces cell cycle arrest, apoptosis and autophagy in breast cancer cells. [PDF]
Plants are an invaluable source of potential new anti-cancer drugs. Here, we investigated the cytotoxic activity of the acetonic extract of Buxus sempervirens on five breast cancer cell lines, MCF7, MCF10CA1a and T47D, three aggressive triple positive ...
Ait-Mohamed O +11 more
europepmc +2 more sources
Antiprotozoal Nor-Triterpene Alkaloids from Buxus sempervirens L. [PDF]
Malaria and human African trypanosomiasis (HAT; sleeping sickness) are life-threatening tropical diseases caused by protozoan parasites. Due to limited therapeutic options, there is a compelling need for new antiprotozoal agents.
Szabó LU +3 more
europepmc +2 more sources
The genome sequence of common box, <i>Buxus sempervirens</i> L. (Buxaceae). [PDF]
We present a genome assembly from an individual Buxus sempervirens (common box; Streptophyta; Magnoliopsida; Buxales; Buxaceae). The genome sequence has a total length of 676.70 megabases.
Christenhusz MJM +10 more
europepmc +2 more sources
Presence of Inulin-Type Fructo-Oligosaccharides and Shift from Raffinose Family Oligosaccharide to Fructan Metabolism in Leaves of Boxtree (Buxus sempervirens). [PDF]
from raffinose family oligosaccharide to fructan metabolism in leaves of boxtree (Buxus sempervirens) Wim Van den Ende1,* Marlies Coopman1, Rudy Vergauwen1, André Van Laere11 KU Leuven, Laboratory of Molecular Plant Biology, Institute of Botany and ...
Van den Ende W +3 more
europepmc +2 more sources
Comparative metabolomics reveals how the severity of predation by the invasive insect Cydalima perspectalis modulates the metabolism re-orchestration of native Buxus sempervirens. [PDF]
Combining NMR– and LC–HRMS–based metabolomics reveals that root and leaf metabolic changes in boxwood predated by box–tree moth occur at the same density of predation for both central and specialized metabolisms. Abstract The recent biological invasion of box tree moth Cydalima perspectalis on Buxus trees has a major impact on European boxwood stands ...
Hay AE +12 more
europepmc +2 more sources
Buxus sempervirens Common Boxwood
This document provides a comprehensive overview of the common boxwood (Buxus sempervirens), detailing its characteristics, growth habits, and uses in landscaping. It describes the plant’s physical attributes, including its height, spread, leaf arrangement, and flower characteristics.
Edward Gilman
doaj +4 more sources

