Results 271 to 280 of about 60,574,786 (305)
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White collar proteins: PASsing the light signal in Neurospora crassa
Trends in Microbiology, 1997The filamentous fungus Neurospora crassa is an excellent paradigm for the study of blue light signal transduction. The isolation and characterization of the genes for two central regulators of the blue light response, white collar-1 and white collar-2, have begun to shed light on the mechanism of blue light signal transduction in fungi.
BALLARIO, Paola, MACINO, Giuseppe
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Recombinant clotting protein passes trials
Chemical & Engineering News Archive, 1991An international clinical study of recombinant blood clotting factor VIII in 107 hemophiliacs indicates that the genetically engineered material is at least as effective as protein isolated from blood plasma. This result will help pave the way for approval by the Food & Drug Administration of a hemophilia therapy free of risk of contamination by AIDS ...
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Requirements for band-pass activation of Ca2+-sensitive proteins such as NFAT
Biophysical Chemistry, 2019Several proteins are sensitive to frequency-modulated oscillations of calcium levels. Most of them exhibit increased activities for faster frequencies, a characteristic here referred to as high-pass activation. In contrast, the transcription factor NFAT is optimally activated at a specific frequency, a behaviour we call band-pass activation.
Arne, Schoch, Jürgen, Pahle
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Passing Prion Proteins to the Cell Next Door
Science's STKE, 2002Liu et al. observed the transfer of glycophosphatidylinositol (GPI)-anchored proteins, including the cellular prion protein (PrP c ), between cells, a process that may have implications for the pathogenesis of prion diseases. PrP c , a glycoprotein anchored to the cell
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Protein Concentration With Single-Pass Tangential Flow Filtration (SPTFF)
Journal of Membrane Science, 2011Abstract This paper presents a novel Cadence™ single-pass tangential flow filtration (SPTFF) process for protein concentration, operating in a continuous mode. The main advantages of the SPTFF technology have been highlighted in a benchmark comparison test versus conventional TFF.
Catherine Casey +4 more
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NMR structure of a full‐length single‐pass membrane protein NRADD
Proteins: Structure, Function, and Bioinformatics, 2019AbstractStructural study of any single‐pass membrane protein is both an important and challenging task. In this report, we present the structure of a neurotrophin receptor‐alike death‐domain protein. The structure and dynamics of the protein was investigated by conventional nuclear magnetic resonance techniques in the solution of phospholipid bicelles.
Kirill D. Nadezhdin +3 more
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Single-molecule detection of proteins passing through solid state nanopores
2013 6th International Conference on Biomedical Engineering and Informatics, 2013Nanopores have been proven as versatile single-molecule sensors for individual unlabeled biopolymer detection and characterization. Besides application to next gene sequencing, proteins are becoming a prime target of investigation. In our work, single molecules of bovine serum albumin have been detected as the transient current blockages while the ...
Lingzhi Wu +4 more
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Smoothelin and Intermediate Filament Proteins in Humanaortocoronary Saphenous Vein By-pass Grafts
The Histochemical Journal, 1999The aim of this immunohistochemical investigation was to study the distribution of the novel cytoskeletal protein smoothelin and the intermediate filament proteins vimentin and desmin in normal human great saphenous vein and in human aortocoronary by-pass vein grafts.
B, Johansson +3 more
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Passing the first milestone in protein design
"Protein Engineering, Design and Selection", 1988openaire +2 more sources