Protein–Protein and Protein–Membrane Associations in the Lignin Pathway [PDF]
Supramolecular organization of enzymes is proposed to orchestrate metabolic complexity and help channel intermediates in different pathways. Phenylpropanoid metabolism has to direct up to 30% of the carbon fixed by plants to the biosynthesis of lignin precursors. Effective coupling of the enzymes in the pathway thus seems to be required.
Bassard, Jean-Etienne +13 more
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Hydrophobic folding units at protein‐protein interfaces: Implications to protein folding and to protein‐protein association [PDF]
AbstractA hydrophobic folding unit cutting algorithm, originally developed for dissecting single‐chain proteins, has been applied to a dataset of dissimilar two‐chain protein‐protein interfaces. Rather than consider each individual chain separately, the two‐chain complex has been treated as a single chain.
C J, Tsai, R, Nussinov
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Electrostatics in protein–protein docking [PDF]
AbstractA novel geometric‐electrostatic docking algorithm is presented, which tests and quantifies the electrostatic complementarity of the molecular surfaces together with the shape complementarity. We represent each molecule to be docked as a grid of complex numbers, storing information regarding the shape of the molecule in the real part and ...
Alexander, Heifetz +2 more
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Recruitment of proteins to modulate protein-protein interactions
The use of a 'borrowed' protein surface to either enhance or inhibit the interaction of a small ligand with its protein target has been reported recently. This approach represents a general method for modulating protein-protein interactions and may find many applications in both biology and medicine.
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Study on nutritional status and incidence of sarcopenia in elderly patients with chronic heart failure. [PDF]
Song S, Du H, Lu X, Luo B, Li Z.
europepmc +1 more source
Short communication: performance of beef cows fed Kernza intermediate wheatgrass straw mixed with alfalfa haylage. [PDF]
Pizarro DM +3 more
europepmc +1 more source
Redox signals and oxidative stress in the control of mitochondrial protein import. [PDF]
Hasberg L +3 more
europepmc +1 more source
Vagus Nerve Stimulation Paired With Tones Alters the Auditory Cortex Proteome in a Rat Model of Rett Syndrome. [PDF]
Myers IK +6 more
europepmc +1 more source
Fusion protein condensate formation via coiled-coil domains. [PDF]
Narayan OP +5 more
europepmc +1 more source

