The role of galectins in virus infection - A systemic literature review
Journal of Microbiology, Immunology and Infection, 2020 Background: Galectins are β-Galactose binding lectins expressed in numerous cells and play multiple roles in various physiological and cellular functions. However, few information is available regarding the role of galectins in virus infections. Here, we
Wen-Hung Wang +2 more
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Utilization of Galectins by Pathogens for Infection
Frontiers in Immunology, 2020 Galectins are glycan-binding proteins which are expressed by many different cell types and secreted extracellularly. These molecules are well-known regulators of immune responses and involved in a broad range of cellular and pathophysiological functions.
Diyoly Ayona +2 more
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Multifaceted roles of Galectins: from carbohydrate binding to targeted cancer therapy [PDF]
Biomarker ResearchGalectins play pivotal roles in cellular recognition and signaling processes by interacting with glycoconjugates. Extensive research has highlighted the significance of Galectins in the context of cancer, aiding in the identification of biomarkers for ...
Nan Zhang +6 more
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Galectin-12 in Cellular Differentiation, Apoptosis and Polarization. [PDF]
, 2018 Galectin-12 is a member of a family of mammalian lectins characterized by their affinity for β-galactosides and consensus amino acid sequences. The protein structure consists of a single polypeptide chain containing two carbohydrate-recognition domains ...
Liu, Fu-Tong, Wan, Lei, Yang, Ri-Yao
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Placental Galectins in Cancer: Why We Should Pay More Attention
Cells, 2023 The first studies suggesting that abnormal expression of galectins is associated with cancer were published more than 30 years ago. Today, the role of galectins in cancer is relatively well established.
Camille Fuselier +8 more
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Intracellular galectins sense cytosolically exposed glycans as danger and mediate cellular responses
Journal of Biomedical Science, 2021 Galectins are animal lectins that recognize carbohydrates and play important roles in maintaining cellular homeostasis. Recent studies have indicated that under a variety of challenges, intracellular galectins bind to host glycans displayed on damaged ...
Ming-Hsiang Hong +4 more
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Galectin functions in cancer-associated inflammation and thrombosis
Frontiers in Cardiovascular Medicine, 2023 Galectins are carbohydrate-binding proteins that regulate many cellular functions including proliferation, adhesion, migration, and phagocytosis. Increasing experimental and clinical evidence indicates that galectins influence many steps of cancer ...
Linus Kruk +7 more
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Galectins and galectin-mediated autophagy regulation: new insights into targeted cancer therapy
Biomarker Research, 2023 Galectins are animal lectins with specific affinity for galactosides via the conserved carbohydrate recognition domains. Increasing studies recently have identified critical roles of galectin family members in tumor progression.
Dan Liu, Hongtao Zhu, Chuanzhou Li
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Galectins: Double-edged Swords in the Cross-roads of Pregnancy Complications and Female Reproductive Tract Inflammation and Neoplasia [PDF]
Journal of Pathology and Translational Medicine, 2015 Galectins are an evolutionarily ancient and widely expressed family of lectins that have unique glycan-binding characteristics. They are pleiotropic regulators of key biological processes, such as cell growth, proliferation, differentiation, apoptosis ...
Nandor Gabor Than +9 more
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Galectins - Important players of the immune response to CNS parasitic infection
Brain, Behavior, & Immunity - Health, 2021 Galectins are a family of proteins that bind β-galactosides and play key roles in a variety of cellular processes including host defense and entry of parasites into the host cells. They have been well studied in hosts but less so in parasites.
Marta Maruszewska-Cheruiyot +2 more
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