Results 21 to 30 of about 13,626 (296)

Human Galectins Induce Conversion of Dermal Fibroblasts into Myofibroblasts and Production of Extracellular Matrix: Potential Application in Tissue Engineering and Wound Repair [PDF]

, 2011
Members of the galectin family of endogenous lectins are potent adhesion/growth-regulatory effectors. Their multi-functionality opens possibilities for their use in bioapplications. We studied whether human galectins induce the conversion of human dermal
André A., S., André K., S., Barbora Dvořánková, Bergmann J., M., Cheb Y.-Y., S.-J., Dam T.K., Demetter O., P., Dvoránková J., B., Engelhardt H.-J., R., Eva Sykova, Fischer H., C., Fritz A., P., Hans-Joachim Gabius, Herbert Kaltner, Hung C.W., Jana Uhrova, Jones D.L., Jones G.E., Jones G.E., Karel Smetana, Jr., Kim Y.-B., H.-W., Kojima S., S., Lacina H., L., Lacina J., L., Lataillade T., J.-J., Legendre N., H., Lensch A., M., Lu J., Z.-H., Lukas Lacina, Miller S.N., Nagy I., N., Nakachi Y., K., Nogales-Gonzalés A., A., O’Donoghue J., K., Pavol Szabo, Pei S., Z., Peter Gal, Sabine André, Sanchez-Ruderisch C., H., Sanchez-Ruderisch S., H., Sansone S., F., Seyrek H., K., Smetana B., K., Smetana L., K., Smetana Z., K., Tomas Zima, Uchida K., K., von Reitzenstein J., C.   +47 more
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Assessment of galectins -1, -3, -4, -8, and -9 expression in ovarian carcinoma patients with clinical implications

World Journal of Surgical Oncology, 2022
Background and aim Galectins have been recently tackled by many researchers in the field of cancer due to their role in tumorigenesis, disease progression, and metastasis.
Radwa Mansour Mohamed, Athar Emam, Mahmoud M. Abdelfattah, Abdel-Mageed Ismail Abdel-Mageed, Mohamed A. Abdelhafeez, Reham Helwa   +5 more
doaj   +1 more source

The Third Dimension of Reading the Sugar Code by Lectins [PDF]

, 2013
Coding of biological information is not confined to nucleic acids and proteins. Endowed with the highest level of structural versatility among biomolecules, the glycan chains of cellular glycoconjugates are well-suited to generate molecular messages ...
André, Sabine, Gabius, Hans-Joachim, Murphy, Paul V.   +2 more
core   +3 more sources

Prognostic significance of endogenous adhesion/growth-regulatory lectins in lung cancer [PDF]

, 2005
Objective: To determine the expression of endogenous adhesion/growth-regulatory lectins and their binding sites using labeled tissue lectins as well as the binding profile of hyaluronic acid as an approach to define new prognostic markers.
Akos Horvath, Andre S, Andre S, Andre S, Andre S, Andre S, Arnusch CJ, Buttery R, Elad-Sfadia G, Gabius HJ, Gabius HJ, Gabius HJ, Hans-Joachim Gabius, Imre Trojan, Jan-Dirk Baumhäkel, Jozsef Furak, Kaltner H, Kayser K, Kayser K, Kayser K, Kayser K, Klaus Kayser, Kopitz J, Kornelia Szluha, Lahm H, Laszlo Tiszlavicz, Liu FT, Moon BK, Nangia-Makker P, Puglisi F, Rappl G, Rorive S, Sabine Andre, Sheikholeslam-Zadeh R, Siebert HC, Tamas Szöke   +35 more
core   +1 more source

Regulated expression of galectin-1 after in vitro productive infection with herpes simplex virus type 1: implications for T cell apoptosis [PDF]

, 2005
Apoptosis of cytotoxic T lymphocytes by herpes simplex virus type-1 (HSV-1) has been reported to be a relevant mechanism of viral immune evasion. Galectin-1 (Gal-1), an endogenous lectin involved in T-cell apoptosis, has recently gained considerable ...
Gonzalez, Maria Ines, Ilarregui, Juan Martin, Rabinovich, Gabriel Adrián, Rubinstein, Natalia, Sanjuan, Norberto Aníbal, Toscano, Marta Alicia   +5 more
core   +1 more source

Galectin Family Members: Emerging Novel Targets for Lymphoma Therapy?

Frontiers in Oncology, 2022
The galectin family of proteins has high affinity with β-galactoside-containing glycans. These proteins participate in cell growth and differentiation, cell adhesion, cell signal transduction, cell apoptosis, and other cellular activities.
Yuanwei Shi, Yuanwei Shi, Danting Tang, Danting Tang, Xiaoqi Li, Xiaoqi Li, Xiaoli Xie, Yufu Ye, Yufu Ye, Lijuan Wang, Lijuan Wang   +10 more
doaj   +1 more source

Symmetric dithiodigalactoside: strategic combination of binding studies and detection of selectivity between a plant toxin and human lectins [PDF]

, 2011
Thioglycosides offer the advantage over O-glycosides to be resistant to hydrolysis. Based on initial evidence of this recognition ability for glycosyldisulfides by screening dynamic combinatorial libraries, we have now systematically studied ...
Aguilera, Ahmad, Alonso-Plaza, André, André, André, André, André, André, André, André, Bachhawat-Sikdar, Barkley, Bayly, Beatriz de Pascual-Teresa, Beer, Bharadwaj, Bianchet, Borrok, Caraballo, Czifrák, Darden, Davis, De Waard, Dolores Solís, Eliza Buzamet, F. Javier Cañada, Fernandez-Alonso, Gabius, Gabius, Gabius, Gabius, Gabius, Gabius, Galanina, Gilleron, Gloria Fernández-Cureses, Gupta, Hans-Joachim Gabius, Hartley, Hilaire, Hotchkiss, Jesús Jiménez-Barbero, Jiménez, Jiménez, Jiménez, Jiménez-Barbero, João P. Ribeiro, Karla Ramírez-Gualito, Kiefel, Kolympadi, Kopitz, Krzeminski, Kübler, Langbein, Lee, Lee, Leyden, López-Lucendo, Margarita Menéndez, Maria Morando, Morris, Muñoz, Olof Ramström, Pei, Ramkumar, Ramström, Ramström, Ribeiro, Ribeiro, Rivera-Sagredo, Roda, Rorive, Rémi Caraballo, Sabine André, Sanchez-Ruderisch, Schmidt, Schwarz, Schweizer, Siebert, Solís, Solís, Sonsoles Martín-Santamaría, Sparrow, Stannard, Stirpe, Strino, Strino, Szilágyi, Szilágyi, Villalobo, Wu   +91 more
core   +2 more sources

Galectin-1 and Galectin-3 in Chronic Pancreatitis [PDF]

Laboratory Investigation, 2000
Galectin-1 and galectin-3 have important functions in cell-cell interactions, cell adhesion to extracellular matrix, the organization of extracellular matrix, and tissue remodeling. To assess their potential role in chronic pancreatitis (CP), we examined their expression by Northern blot analysis, in situ hybridization, immunohistochemistry, and ...
L, Wang, H, Friess, Z, Zhu, L, Frigeri, A, Zimmermann, M, Korc, P O, Berberat, M W, Büchler   +7 more
openaire   +2 more sources

Comparative analysis of galectin-1, galectin-3, and galectin-8 signatures in normal and choriocarcinoma trophoblast cell lines [PDF]

Archives of Biological Sciences
Galectins are found in the placenta during both normal and pathological conditions. Specifically, galectins -1, -3, and -8 have been identified in extravillous trophoblast cells, with galectins -1, and -3 playing notable roles in trophoblast cell ...
Jovanović Krivokuća Milica, Legner Janko, Ćujić Danica, Vilotić Aleksandra, Grubiša Ivana, Vićovac Ljiljana, Bojić-Trbojević Žanka   +6 more
doaj   +1 more source

Predictive biomarkers for checkpoint inhibitor-based immunotherapy: The Galectin-3 signature in NSCLCs [PDF]

, 2019
Checkpoint inhibitor-based immunotherapy is opening a promising scenario in oncology, with objective responses registered in multiple cancer types. However, reliable predictive markers of tumor responsiveness are still lacking.
Bartolazzi A., Capalbo C., Filetti M., Marchetti P., Scafetta G.   +4 more
core   +1 more source