Results 21 to 30 of about 9,659 (276)
, 2013 Galectins are glycan-binding proteins implicated in intracellular signaling, cell-cell communication, cellular proliferation and survival. These endogenous lectins have emerged as key players in the tumor microenvironment. They are expressed and released
Victoria Sundblad +3 more
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Galectins - Important players of the immune response to CNS parasitic infection
Brain, Behavior, & Immunity - Health, 2021 Galectins are a family of proteins that bind β-galactosides and play key roles in a variety of cellular processes including host defense and entry of parasites into the host cells. They have been well studied in hosts but less so in parasites.
Marta Maruszewska-Cheruiyot +2 more
doaj +1 more source
Biomolecules, 2021 Galectins bind various pathogens through recognition of distinct carbohydrate structures. In this work, we examined the binding of four human galectins to the Gram-negative bacteria Klebsiella pneumoniae (Kpn) and non-typeable Haemophilus influenzae ...
María A. Campanero-Rhodes +7 more
doaj +1 more source
Galectins in the Tumor Microenvironment: Focus on Galectin-1 [PDF]
, 2020 In the last decades, the focus of cancer research has moved from epithelial cells to the tumor milieu, in an effort to better understand tumor development and progression, and with the important end goal of translating this knowledge into effective therapies.
Neus, Martínez-Bosch, Pilar, Navarro
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Galectin-1 and Galectin-3 in Chronic Pancreatitis [PDF]
Laboratory Investigation, 2000 Galectin-1 and galectin-3 have important functions in cell-cell interactions, cell adhesion to extracellular matrix, the organization of extracellular matrix, and tissue remodeling. To assess their potential role in chronic pancreatitis (CP), we examined their expression by Northern blot analysis, in situ hybridization, immunohistochemistry, and ...
Wang L +7 more
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Role of Human Galectins in Inflammation and Cancers Associated with Endometriosis
Biomolecules, 2020 Galectins are a family of β-galactoside-binding proteins that contribute to multiple cellular functions, including immune surveillance and apoptosis.
Brooke V. Hisrich +6 more
doaj +1 more source
Hematology, 2023 Background Galectin (Gal) is considered a promising immune checkpoint molecule. More and more studies have shown that high expression levels of galectins in hematologic cancer are positively correlated with poor clinical prognosis.
Haotian Liu +4 more
doaj +1 more source
Human Galectins Induce Conversion of Dermal Fibroblasts into Myofibroblasts and Production of Extracellular Matrix: Potential Application in Tissue Engineering and Wound Repair [PDF]
, 2011 Members of the galectin family of endogenous lectins are potent adhesion/growth-regulatory effectors. Their multi-functionality opens possibilities for their use in bioapplications. We studied whether human galectins induce the conversion of human dermal
Lacina, Lukas +21 more
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Pregnancy Galectinology: Insights Into a Complex Network of Glycan Binding Proteins
Frontiers in Immunology, 2019 Galectins are a phylogenetically conserved family of soluble β-galactoside binding proteins, consisting of 15 different types, each with a specific function.
Sandra M. Blois +6 more
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Cell Biology of Galectins [PDF]
, 2022 Galectins are a family of soluble beta-galactoside-binding proteins with diverse glycan-dependent and glycan-independent functions outside and inside the cell.
core +1 more source