Results 11 to 20 of about 9,887 (270)
Journal of Cell Science, 2018 Galectins are carbohydrate-binding proteins that are involved in many physiological functions, such as inflammation, immune responses, cell migration, autophagy and signalling.
Jacob, Ralf, +3 more
core +5 more sources
Brain Pathology, 2010 Malignant gliomas, especially glioblastomas, are associated with a dismal prognosis. Despite advances in diagnosis and treatment, glioblastoma patients still have a median survival expectancy of only 14 months.
Kiss, Robert +4 more
core +4 more sources
The Role of Galectins as Modulators of Metabolism and Inflammation [PDF]
Mediators of Inflammation, 2018 Galectins are β-galcotosid-binding lectins. The function of galectins varies with their tissue-specific and subcellular location, and their binding to carbohydrates makes them key players in several intra- and extracellular processes where they bind to ...
Monica Fengsrud Brinchmann +2 more
doaj +2 more sources
Galectins and cutaneous immunity
Dermatologica Sinica, 2012 Galectins are highly expressed in epithelial cells and immune cells. In skin, they can be detected in keratinocytes, melanocytes, dendritic cells, macrophages, and T cells. Galectins are present outside and inside the cells and thus may exhibit different
Huan-Yuan Chen +4 more
doaj +2 more sources
Role of Human Galectins in Inflammation and Cancers Associated with Endometriosis
Biomolecules, 2020 Galectins are a family of β-galactoside-binding proteins that contribute to multiple cellular functions, including immune surveillance and apoptosis.
Brooke V. Hisrich +6 more
doaj +2 more sources
Galectins in the Pathogenesis of Cerebrovascular Accidents: An Overview
Journal of Experimental Neuroscience, 2019 Due to limitations of neuroimaging, such as the isodense appearance of blood to neuronal tissue in subacute hemorrhagic stroke, a body of studies have been performed to evaluate candidate biomarkers which may aid in accurate determination of ...
William F Abel +2 more
doaj +2 more sources
Targeting Galectins With Glycomimetics [PDF]
Frontiers in Chemistry, 2020 Among glycan-binding proteins, galectins, β-galactoside-binding lectins, exhibit relevant biological roles and are implicated in many diseases, such as cancer and inflammation.
Sara Bertuzzi +6 more
doaj +6 more sources
Galectins: Key Players in the Tumor Microenvironment
, 2013 Galectins are glycan-binding proteins implicated in intracellular signaling, cell-cell communication, cellular proliferation and survival. These endogenous lectins have emerged as key players in the tumor microenvironment. They are expressed and released
Victoria Sundblad +8 more
core +2 more sources
Current Biology, 2022 Banfer and Jacob introduce us to galectins - β-galactoside-binding lectins - and their range of functions in multicellular organisms.
Sebastian, Bänfer, Ralf, Jacob
+7 more sources
Cell Biology of Galectins [PDF]
, 2022 Galectins are a family of soluble beta-galactoside-binding proteins with diverse glycan-dependent and glycan-independent functions outside and inside the cell.
core +1 more source