Results 181 to 190 of about 3,260,333 (285)

Nutritional contents, nutritional quality and manufacturer of ready foods in China: a cross-sectional study of 2087 food products. [PDF]

Nutr Diabetes
Wang T, Xin Y, Liu X, Ye P, Peng S, Yin S, Liang J, Booth L, Law K, Trieu KK, Pettigrew S, Wu JH, Tian M.   +12 more
europepmc   +1 more source

Some By-Products of Pre-Trial [PDF]

, 1956
Nims, Harry D.
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Mapping and Nutrient Profiles of Commercially Produced Complementary Foods in West Africa. [PDF]

Matern Child Nutr
Diongue A, Mama OM, Souho T, Kouton SLE, Fofana A, Diagana YS, Issa MY, Sadou H, Kou'santa AS, Hounkpatin WA, Laillou A, Nanama S, Faye MH, Diouf A, Idohou-Dossou N.   +14 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Excessive manganese content in children's multivitamin supplements: Potential for neurodevelopmental harm and other adverse health outcomes. [PDF]

PLoS One
Frisbie SH, Mitchell EJ, Hoeltge A, Pett LA, Hoeltge MG.   +4 more
europepmc   +1 more source

Bulk Storage: Postponement of Agricultural By-Products [PDF]

, 2016
Castro, Hugo Alfredo
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Herbal smoking products: A neglected frontier in global tobacco control. [PDF]

Tob Induc Dis
Rewatkar K, Kokane N, Khatri S.
europepmc   +1 more source