Results 91 to 100 of about 117,695 (339)

Just-in-Time Memoryless Trust for Crowdsourced IoT Services

, 2020
We propose just-in-time memoryless trust for crowdsourced IoT services. We leverage the characteristics of the IoT service environment to evaluate their trustworthiness. A novel framework is devised to assess a service's trust without relying on previous
Bahutair, Mohammed, Bouguettaya, Athman, Neiat, Azadeh Ghari   +2 more
core   +1 more source

Macrophage transactivation for chemokine production identified as a negative regulator of granulomatous inflammation using agent-based modeling [PDF]

, 2018
Cellular activation in trans by interferons, cytokines and chemokines is a commonly recognized mechanism to amplify immune effector function and limit pathogen spread. However, an optimal host response also requires that collateral damage associated with
Andrews, Paul S., Beattie, Lynette, Hoehme, Stefan, Kaye, Paul M., Moore, John W. J., Moyo, Daniel, Sampson, Adam T., Sawtell, Amy, Timmis, Jon   +8 more
core   +5 more sources

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Radiation Bystander Effects Mechanism

Iranian Journal of Medical Physics, 2009
Introduction: Radiation Induced Bystander Effect (RIBE) which cause radiation effects in non-irradiated cells, has challenged the principle according to which radiation traversal through the nucleus of a cell is necessary for producing biological responses. What is the mechanism of this phenomenon?
Soleymanifard, Shokohzaman, Bahreyni Toossi, Mohammad Taghi   +1 more
openaire   +2 more sources

Agglomeration and Aid [PDF]

A key issue in development economics is the explanation of core-periphery patterns around the world. Combining this issue with that of analyzing unilateral transfers (e.g.
Charles van Marrewijk, Harry Garretsen, Steven Brakman   +2 more
core  

CD3ɛ Nanobody‐Engineered Extracellular Vesicles Driving In Vivo Generation of BiTE‐Secreting CAR‐Ts for Solid Tumor Therapy With Memory Response and Minimal Immunogenicity

Advanced Science, EarlyView.
HEK‐293T‐derived CD3ε Nb‐engineered EVs to generate dual‐targeting CAR‐T cells directly in vivo. These EVs selectively deliver CAR.BiTE transgenes into T cells and reprogramed to HLA‐G/PD‐L1‐targeting effector cells with enhanced memory and persistence.
Shi‐Wei Huang, Yu‐Chuan Lin, Chih‐Ming Pan, Yeh Chen, Ming‐You Shie, Cheng‐Yu Chen, Kai‐Wen Kan, Yi‐Wen Chen, Ming‐Chao Liu, Chung‐Chun Wu, Yu‐Ting Chiang, Huai‐Ping Ho, Chen‐Yu Lin, Pei‐Ying Lin, Yu‐Han Huang, Steffany Rusli, Wan‐Yu Mao, Pei‐Wen Huang, Sin‐Ting Wang, Wan‐Chen Tsai, Ya‐Hsu Chiu, Ting‐Hsun Lin, Wan‐Ling Chiang, Che‐Kai Chang, Zi‐Lun Lai, Mei‐Chih Chen, Shao‐Chih Chiu, Der‐Yang Cho   +27 more
wiley   +1 more source

An update on the impact of bystander cardiopulmonary resuscitation on favorable neurological outcomes of patients with out-of-hospital cardiac arrest accounting for effect modification by witnessed arrest: a post hoc analysis of the SOS-KANTO 2017 study

Resuscitation Plus
Aim: To investigate the role of witnessed arrest as an effect modifier on neurological outcomes following bystander cardiopulmonary resuscitation (CPR) in patients with out-of-hospital cardiac arrest (OHCA). Methods: This cohort study was conducted using
Hideki Endo, Takahiro Miyoshi, Hiroyuki Yamamoto, Nobuya Kitamura, Takashi Tagami, Kiyotsugu Takuma, Kiyoshi Murata   +6 more
doaj   +1 more source

Structural problems without structural solutions? Youth leaders' perceptions of their community

American Journal of Community Psychology, EarlyView.
Abstract As young people explore and reflect on the conditions of their neighborhoods and communities, they can forge a critical consciousness—merging their perspectives and analysis to direct both individual and collective actions. Photovoice is a methodological tool that allows participants to document their perspectives and analysis and discuss with
Linnea L. Hjelm, Aishia A. Brown, Benjamin W. Fisher, Alice Story, Nubia Bennett   +4 more
wiley   +1 more source

College Students’ Perceptions of Barriers to Bystander Intervention [PDF]

, 2017
Sexual violence is a major problem on college campuses and is associated with a range of negative health consequences for victims. Teaching students to intervene as prosocial bystanders has become a common element of sexual assault prevention efforts ...
Grych, John H., Yule, Kristen
core   +1 more source

Understanding Youth Assaults of Police Officers in Australia: A Power Threat Meaning Framework Analysis

Australian Journal of Social Issues, EarlyView.
ABSTRACT This study explores youth violence towards police officers in Australia through the Power Threat Meaning Framework (PTMF) to better understand the underlying factors contributing to such violence; focusing on power dynamics, childhood adversity, and trauma.
Dimitra Lattas, Kelly Hine, Catherine Creamer, Kelley Burton, Katelyn Davenport‐Klunder   +4 more
wiley   +1 more source