Results 131 to 140 of about 117,695 (339)

The hidden regulators: Non‐coding RNAs in KMT2A‐rearranged acute lymphoblastic leukemia

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Acute lymphoblastic leukemia (ALL) driven by KMT2A rearrangements (KMT2A‐r) is an aggressive hematologic malignancy with poor prognosis and a high incidence in infants. While KMT2A fusion proteins drive leukemogenesis through transcriptional dysregulation, recent discoveries have highlighted the pivotal role of non‐coding RNAs (ncRNAs) in ...
Maria Augusta Poersch   +5 more
wiley   +1 more source

Social Movements and HR: The Impact of #MeToo [PDF]

open access: yes, 2018
[Excerpt] Considering the increased societal attention given to sexual harassment and assault, and the wide range of reactions to #MeToo, we wanted to know how companies are reacting, whether they are changing their policies and practices, and whether ...
Boyle, David, Cucchiara, Amanda
core   +1 more source

Clinical trial of safety and antitumor activity of farletuzumab ecteribulin in patients with platinum‐resistant ovarian cancer: Phase I expansion results

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective In the dose‐escalation part of Study 101, which included multiple tumor types, objective responses were observed in 10 of 22 patients across multiple dose levels of farletuzumab ecteribulin (FZEC). We explored the safety/antitumor activity of FZEC in patients with platinum‐resistant ovarian cancer (PROC) from the Study 101 expansion ...
Kan Yonemori   +11 more
wiley   +1 more source

CAT‐BLAST: Engineered bacteria for robust targeting and elimination of cancer‐associated fibroblasts

open access: yesiMeta, EarlyView.
Cancer‐associated fibroblasts (CAFs) construct a protective stromal barrier that promotes tumor growth and resistance to therapy. To dismantle this, we developed CAT‐BLAST, an engineered bacterial platform designed to potently eliminate these cells. We engineered a safe, high‐expression E.
Mengdi Xu   +7 more
wiley   +1 more source

The situational Samaritan: How group reputation threat shapes reparatory behavior

open access: yesJournal of Consumer Psychology, EarlyView.
Abstract Consumers often act to correct the wrongdoings of people close to them, such as family members or friends. The current research demonstrates that consumers may also engage in a variety of reparatory behaviors—from a simple apology to gift‐giving and tipping—to counter the misdeeds of in‐group strangers when their behavior threatens the ...
Julia Von Schuckmann   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy