Results 161 to 170 of about 117,695 (339)

A Senescence Bystander Effect in Human Lung Fibroblasts. [PDF]

open access: yesBiomedicines, 2021
Waters DW   +12 more
europepmc   +1 more source

NQO1‐Responsive Prodrug for in Cellulo Release of Cytochalasin B as Cancer Cell‐Targeted Migrastatic

open access: yesSmall, EarlyView.
The design, synthesis, biochemical, and cell biological evaluation of the NQO1‐targeted prodrug BQTML‐CB is reported. BQTML‐CB selectively releases cytochalasin B upon activation by the quinone‐oxidoreductase NQO1 associated with invasiveness of cancer cells, representing a novel approach to improve cancer selectivity and reduce immunosuppressive ...
Mervic D. Kagho   +10 more
wiley   +1 more source

Golgi Phosphoprotein 3 Mediates Radiation-Induced Bystander Effect via ERK/EGR1/TNF-α Signal Axis. [PDF]

open access: yesAntioxidants (Basel), 2022
Qin F   +9 more
europepmc   +1 more source

Deciphering the Heterogeneity of Pulmonary Macrophages in Response to Fine Particles

open access: yesSmall, EarlyView.
This study introduces a dual‐labeled gold nanoparticle model to capture particle–responsive cells via integrating fluorescence‐activated cell sorting and single‐cell RNA sequencing. Fourteen macrophage subsets are identified with response and function heterogeneity, among which AMs_3, AMs_7, and recMacs_4 subsets show stronger phagocytic activation ...
Qing'e Shan   +11 more
wiley   +1 more source

Stand By or Stand Up: Exploring the Biology of the Bystander Effect. [PDF]

open access: yesBiol Psychiatry, 2021
Scott ES, Ross DA, Fenstermacher E.
europepmc   +1 more source

Improving HER2 Diagnostics with Digital Real‐Time PCR for Ultrafast, Precise Prediction of Anti‐HER2 Therapy Response in Patients with Breast Cancer

open access: yesSmall Methods, EarlyView.
This study presents a novel, clinically feasible HER2 testing method using a fully automated digital real‐time PCR platform. It enables real‐time absolute quantification of ERBB2 copy number alterations for rapid, simple, and accurate assessment of HEgR2 status, thereby overcoming the limitations of conventional testing and improving prediction of anti‐
Hee‐Joo Choi   +29 more
wiley   +1 more source

Bystander Effect Studies in HL60 Human Promyelocytes [PDF]

open access: bronze, 2008
Valentina Dini   +5 more
openalex   +1 more source

Who Is the System? On the Externalisation and Depersonalisation of Responsibility for Abuse

open access: yesSystems Research and Behavioral Science, EarlyView.
ABSTRACT This article examines the externalisation and depersonalisation of responsibility in the institutional communication of the Roman Catholic Church in the context of sexualised violence. Niklas Luhmann's theory of social systems is used to show how semantic constructions such as ‘systemic causes’ rhetorically blur responsibility and contribute ...
Thomas Kron
wiley   +1 more source

Radiation-Induced Bystander Effect Mediated by Exosomes Involves the Replication Stress in Recipient Cells. [PDF]

open access: yesInt J Mol Sci, 2022
Smolarz M   +5 more
europepmc   +1 more source

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