A novel bystander effect in tamoxifen treatment: PPIB derived from ER+ cells attenuates ER− cells via endoplasmic reticulum stress-induced apoptosis [PDF]
Cell Death and DiseaseTamoxifen (TAM) is the frontline therapy for estrogen receptor-positive (ER+) breast cancer in premenopausal women that interrupts ER signaling. As tumors with elevated heterogeneity, amounts of ER-negative (ER−) cells are present in ER+ breast cancer ...
Tinglin Yang +6 more
doaj +2 more sources
Astragaloside IV protects LO2 cells from oxidative damage caused by radiation-induced bystander effect through Akt/Nrf2 pathway. [PDF]
Toxicol Res (Camb), 2023 Wan D +7 more
europepmc +3 more sources
Bystander Effect Induced in Breast Cancer (MCF-7) and Human Osteoblast Cell Lines (hFOB 1.19) with HDR-Brachytherapy [PDF]
Journal of Biomedical Physics and Engineering, 2020 Background: Radiation induced bystander effects (RIBEs) occurs in unirradiated cells exhibiting indirect biological effect as a consequence of signals from other irradiated cells in the population.
N H Mohd Zainudin +2 more
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Exosome-mediated modulation of radioresistance: The radiation-induced bystander effect in prostate cancer cells [PDF]
PLoS OnePszczółkowska–Kępa B +5 more
europepmc +3 more sources
Cx43 channels and signaling via IP3/Ca2+, ATP, and ROS/NO propagate radiation-induced DNA damage to non-irradiated brain microvascular endothelial cells [PDF]
, 2020 Radiotherapeutic treatment consists of targeted application of radiation beams to a tumor but exposure of surrounding healthy tissue is inevitable.
Bultynck, Geert +10 more
core +1 more source
Exosomes are released by bystander cells exposed to radiation-induced biophoton signals: Reconciling the mechanisms mediating the bystander effect. [PDF]
PLoS ONE, 2017 OBJECTIVE:The objective of our study was to explore a possible molecular mechanism by which ultraviolet (UV) biophotons could elicit bystander responses in reporter cells and resolve the problem of seemingly mutually exclusive mechanisms of a physical UV
Michelle Le +5 more
doaj +1 more source
TakeCARE, a Video to Promote Bystander Behavior on College Campuses: Replication and Extension [PDF]
, 2017 Previous research has demonstrated that college students who view TakeCARE, a video bystander program designed to encourage students to take action to prevent sexual and relationship violence (i.e., bystander behavior), display more bystander behavior ...
Caiozzo, Christina +8 more
core +2 more sources
Neutron exposures in human cells: bystander effect and relative biological effectiveness. [PDF]
PLoS ONE, 2014 Bystander effects have been observed repeatedly in mammalian cells following photon and alpha particle irradiation. However, few studies have been performed to investigate bystander effects arising from neutron irradiation. Here we asked whether neutrons
Isheeta Seth +5 more
doaj +1 more source
Bystander effects and radiotherapy [PDF]
Reports of Practical Oncology & Radiotherapy, 2015 Radiation-induced bystander effects are defined as biological effects expressed after irradiation by cells whose nuclei have not been directly irradiated. These effects include DNA damage, chromosomal instability, mutation, and apoptosis. There is considerable evidence that ionizing radiation affects cells located near the site of irradiation, which ...
Alicia Marín +7 more
openaire +3 more sources
Cell bystander effect induced by radiofrequency electromagnetic fields and magnetic nanoparticles [PDF]
, 2015 Induced effects by direct exposure to ionizing radiation (IR) are a central issue in many fields like radiation protection, clinic diagnosis and oncological therapies.
Asin, L. +4 more
core +3 more sources