Results 221 to 230 of about 117,695 (339)

Profiling of HCAR1 signalling reveals Gαi/o and Gαs activation without β‐arrestin recruitment and the discovery of an allosteric agonist

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Lactate, historically viewed as a metabolic by‐product, has emerged as a signalling molecule via the G protein–coupled receptor Hydroxycarboxylic Acid Receptor 1 (HCAR1). The receptor is primarily expressed in adipocytes but also found in various other tissues.
Simon Lind, Shane C. Wright, Emilia Gvozdenovic, Kristina Nilsson, Kenneth L. Granberg, Michel Bouvier, Linda C. Johansson   +6 more
wiley   +1 more source

Organizational culture moderates the effect of bystander effect and internal control on accounting fraud trends in village credit institutions in Jembrana Regency

, 2022
Ida Bagus Anom Yasa, I Ketut Sukayasa, Ni Made Mega Abdi Utami   +2 more
openalex   +2 more sources

Concerted Cultivation in Canada: Class‐Based Approaches to Parenting

Canadian Review of Sociology/Revue canadienne de sociologie, EarlyView.
ABSTRACT The literature on concerted cultivation describes how higher‐class parents reproduce their social class standing in their children by engaging in ‘cultivating’ parenting practices. I use Latent Class Analysis and multinomial logistic regression applied to survey data from Canada to inductively uncover distinct approaches to parenting and then ...
Gerry Veenstra
wiley   +1 more source

Exosomal MiR-769-5p Exacerbates Ultraviolet-Induced Bystander Effect by Targeting TGFBR1. [PDF]

Front Physiol, 2020
Ni N, Ma W, Tao Y, Liu J, Hua H, Cheng J, Wang J, Zhou B, Luo D.   +8 more
europepmc   +1 more source

Bystander Recovery for Mental Distress [PDF]

, 1969

core   +1 more source

Therapeutic Strategies to Overcome Payload Resistance of Trastuzumab Deruxtecan in HER2‐Positive Cancers

Cancer Science, EarlyView.
Overexpression of ABC transporters, especially ABCG2 and ABCB1, mediates acquired resistance to T‐DXd in HER2‐positive cancers. Inhibition of these transporters restored T‐DXd efficacy, highlighting efflux‐mediated resistance as a potential therapeutic target. ABSTRACT Antibody–drug conjugates (ADCs) are emerging as a promising class of targeted cancer
Yuya Murase, Shigeki Nanjo, Sachiko Arai, Sota Kondo, Hayato Koba, Yifeng Liu, Koji Fukuda, Shigeki Sato, Jun Kinoshita, Noriyuki Inaki, Tsukasa Ueda, Shunichi Nomura, Yuichi Tambo, Takahiro Shimizu, Masafumi Horie, Daichi Maeda, Richard W. Wong, Kazuyoshi Hosomichi, Takafumi Kobayashi, Satoshi Watanabe, Kenta Yamamura, Noriyuki Ohkura, Miki Abo, Seiji Yano   +23 more
wiley   +1 more source

The Range of the Bystander Effect Signal in Three-Dimensional Tissue and Estimation of the Range in Human Lung Tissue at Low Radon Levels

, 2009
Bobby E. Leonard
openalex   +2 more sources

641. TK.007 Mediates Superior Killing Efficiency and Bystander Effect in Cancer Suicide Gene Therapy [PDF]

, 2011

openalex   +1 more source

2010 International consensus on cardiopulmonary resuscitation and emergency cardiovascular care science with treatment recommendations, part 5: adult basic life support [PDF]

, 2010
Botha, Martin, Cave, Diana M, Cudnik, Michael T, Handley, Antony J, Hatanaka, Tetsuo, Hazinski, Mary Fran, Jacobs, Ian, Koster, Rudolph W, Monsieurs, Koenraad, Morley, Peter T, Nolan, Jerry P, Sayre, Michael R, Travers, Andrew H   +12 more
core   +3 more sources

IAP Antagonists Selectively Eliminate Therapy‐Induced Senescent Cancer Cells via TNFα‐Independent Apoptosis

Cancer Science, EarlyView.
Upon chemotherapy, a subset of cancer cells enters a senescent state, referred to as TIS. When IAP antagonists are administered, TIS cells are selectively eliminated through TNFα‐independent apoptosis. TNFα secreted by TIS cancer cells may also act in a paracrine manner to enhance extrinsic apoptosis in neighboring non‐senescent cancer cells.
Hiroaki Ochiiwa, Takeshi Wakasa, Yuki Kataoka, Koji Ando, Eiji Oki, Yoshihiko Maehara, Makoto Iimori, Hiroyuki Kitao   +7 more
wiley   +1 more source