Results 271 to 280 of about 117,695 (339)

Shame in Response to Institutional Failure

open access: yesJournal of Applied Philosophy, EarlyView.
ABSTRACT When an institution morally fails, what is the appropriate emotional reaction for those institution members who are causally uninvolved in bringing about this failure? Our aim in this article is to explain why it may be fitting for such people to feel ashamed about the wrongs perpetrated by the institution. We begin by explaining the main case
Alfred Archer, Benjamin Matheson
wiley   +1 more source

AI Mimicry and Human Dignity: Chatbot Use as a Violation of Self‐Respect

open access: yesJournal of Applied Philosophy, EarlyView.
ABSTRACT This article investigates how human interactions with AI‐powered chatbots may offend human dignity. Current chatbots, driven by large language models, mimic human linguistic behaviour but lack the moral and rational capacities essential for genuine interpersonal respect.
Jan‐Willem van der Rijt   +2 more
wiley   +1 more source

Tracking the Epistemic Harms of Marital Rape: The Case for Experiential Injustice

open access: yesJournal of Applied Philosophy, EarlyView.
ABSTRACT Empirical studies suggest that rape in marriages continues to be treated as a less severe crime than other forms of rape. Although the psychological and legal dimensions of marital rape have received some attention, its epistemic harms remain under‐theorised.
Sushruth Ravish, Ritu Sharma
wiley   +1 more source

Tandem Approach for Transvenous Lead Extraction: Efficacy, Safety, and Operational Learning Curve

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background and Aims The need for transvenous lead extraction (TLE) is rising due to increased cardiovascular device implantation and an aging population. While the superior access is standard, complex cases may benefit from the Tandem approach, combining femoral and superior access to improve efficacy and safety.
Alessio Petrone   +8 more
wiley   +1 more source

The Narrative Continent: Discursive Recognition and the EU's Technological Actorness

open access: yesJCMS: Journal of Common Market Studies, EarlyView.
Abstract Recognition in global politics is not only earned through institutions or capabilities; it is narrated into being. This article investigates how the European Union (EU) is framed as a technological actor in global discourse, focusing on the symbolic dynamics of discursive recognition.
Mahmoud Javadi
wiley   +1 more source

Dysbiosis‐Mediated Inflammation: A Pathophysiological Link Between Rheumatoid Arthritis and Periodontitis

open access: yesJournal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To explore mechanistic links between rheumatoid arthritis (RA) and periodontitis (PD) through the lens of subgingival microbial dysbiosis–mediated inflammation. Methods Subgingival plaque from 100 volunteers with RA and PD (RAPD), 22 with RA (RAnoPD), 18 with PD (PDnoRA) and 19 healthy controls (noRAnoPD) was analysed using 16S‐amplicon ...
Isabel Lopez‐Oliva   +11 more
wiley   +1 more source

scRNA‐Seq reveals anti‐lymphoma immune responses in mogamulizumab‐associated skin eruptions

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
CCR4 was expressed in malignant clones and regulatory T cells in untreated CTCL, that were decreased in MAR. Malignant clones in MAR showed a silenced phenotype with decreases in central memory markers SELL and CCR7, and GTP‐binding member GIMAP7 and upregulation of MMP2 inhibitor TIMP2 and tumour suppressor gene RUNX3.
Shannon Meledathu   +13 more
wiley   +1 more source

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