Results 71 to 80 of about 117,695 (339)

Melatonin Ameliorates The Production of COX-2, iNOS, and The Formation of 8-OHdG in Non-Targeted Lung Tissue after Pelvic Irradiation

open access: yesCell Journal, 2017
In this study, we evaluated the bystander effect of radiation on the regulation of cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS), and 8-hydroxydeoxyguanosine (8-OHdG) in lung tissues of Sprague-Dawley rats with and without pre ...
Reza Fardid   +7 more
doaj   +1 more source

Bystander Effect of Oncothermia

open access: yesConference Papers in Medicine, 2013
Metastatic form of malignant tumor diseases is the most serious problem in oncology and the greatest challenge in tumor therapy. Conventional therapeutical approaches (surgery, irradiation, and chemotherapy) cannot manage this challenge in oncological practice. According to our theory, oncothermia treatment-induced immunogenic tumor cell death can be a
G. Andocs   +4 more
openaire   +1 more source

Logic‐Gated HSV‐TK/GCV Suicide Gene Circuit for Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
The BRAS comprises two modular genetic components driven by distinct tumor‐specific promoters and a failsafe layer with the NOT gate. This multi‐input logic gate circuit enables precise, specific expression of HSV‐TK in breast cancer cells with hardly expression in normal cell and effectively inhibits tumor growth in a triple‐negative breast cancer ...
Shasha Tang   +10 more
wiley   +1 more source

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

open access: yesAdvanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang   +7 more
wiley   +1 more source

Witnessing Cyberbullying and Internalizing Symptoms among Middle School Students

open access: yesEuropean Journal of Investigation in Health, Psychology and Education, 2020
Cyberbullying is a significant problem among school-aged youth. Cyberbullying peaks in middle school with 33% of middle school students reporting cyberbullying victimization and more than 50% reporting witnessing cyberbullying as bystanders. Although the
Diana M. Doumas, Aida Midgett
doaj   +1 more source

The effect of temperature on the bystander effect as examined in human prostate carcinoma cells with alpha particle irradiation [PDF]

open access: yes, 2006
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Nuclear Science and Engineering, 2006."June 2006."Includes bibliographical references (p. 30-32).The bystander effect is seen when irradiated cells release a factor that can produce damage or
Sheppard, Sarah (Sarah Elizabeth)
core  

The volume and source of cyberabuse influences victim blame and perceptions of attractiveness [PDF]

open access: yes, 2018
Cyberabuse is an escalating problem in society, as opportunities for abuse to occur in online public domains increase. Such acts are often defined by the frequency of abuse, and in many cases multiple individuals play a part in the abuse.
Hand, Christopher J.   +2 more
core   +3 more sources

Engineering Compact Base Editors by AlphaFold‐Guided Mutation Scan and Escherichia coli‐Based Tri‐Selection

open access: yesAdvanced Science, EarlyView.
A miniaturized deaminase SsdAtox was scanned with AlphaFold to identify DNA binding pocket hot spots. Site‐saturation mutagenesis at gatekeeper residue K31 yielded ten‐fold activity enhancement. Trinity Screen, an E. coli‐based three‐in‐one platform selecting for high activity and reduced double‐strand breaks, enabled combinatorial evolution at DNA ...
Ryeo Gang Son   +2 more
wiley   +1 more source

Radiation-induced bystander effects [PDF]

open access: yesActa Oncologica, 2006
Ionizing radiation is an important part of cancer therapy and at the molecular and cellular level it is generally believed that damage to the DNA within the cell nucleus is the major cause of repro...
openaire   +1 more source

Aversive Bystander Effect: Egalitarian bystanders’ overestimation of confronting prejudice

open access: yes, 2022
Everyday expression of prejudice continues to pose a social challenge across societies. We tend to assume that to the extent people are egalitarian, they are more likely to confront prejudice - but this might not necessarily be the case. We tested this assumption in two countries (US and Hungary) among majority members of society, using a behavioral ...
Hanna Szekeres   +3 more
openaire   +1 more source

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