Results 81 to 90 of about 117,695 (339)
Supplementary Table 1 from Anetumab Ravtansine: A Novel Mesothelin-Targeting Antibody–Drug Conjugate Cures Tumors with Heterogeneous Target Expression Favored by Bystander Effect [PDF]
, 2023 Sven Golfier +15 more
openalex +1 more source
, 2015 Mechanistic multi-stage models are used to analyze lung-cancer mortality after Plutonium exposure in the Mayak-workers cohort, with follow-up until 2008.
Eidemüller, Markus +2 more
core +2 more sources
Single and fractionated ionizing radiation induce alterations in endothelial connexin expression and channel function [PDF]
, 2019 Radiotherapy is an effective treatment for most tumor types. However, emerging evidence indicates an increased risk for atherosclerosis after ionizing radiation exposure, initiated by endothelial cell dysfunction. Interestingly, endothelial cells express
Aerts, An +8 more
core +2 more sources
Structure‐Guided Engineering of a Cas12i Nuclease Unlocks Near‐PAMless Genome Editing
Advanced Science, EarlyView.CRISPR‐Cas nucleases are limited by PAM requirements, restricting genome accessibility. Structure‐guided engineering of the compact Cas12i nuclease SF01 produced three variants with near‐PAMless, enabling efficient editing at diverse 5'‐NNTN‐3' sites. These nucleases expand the editable portion of the human genome more than fourfold, enabling efficient
Qitong Chen +15 more
wiley +1 more source
Scientific Reports, 2023 Survival following out-of-hospital cardiac arrest (OHCA) remains low, typically less than 10%. Bystander cardiopulmonary resuscitation (CPR) and bystander-AED use have been shown to improve survival by up to fourfold in individual studies.
Kayla M. Simmons +2 more
doaj +1 more source
The Trolley Problem and the Dropping of Atomic Bombs [PDF]
, 2017 In this paper, the ethical and spiritual aspects of the trolley problem are discussed in connection with the dropping of atomic bombs on Hiroshima and Nagasaki.
Morioka, Masahiro
core +3 more sources
Dynamic Decoration of DNA Scaffolds for High‐Resolution Cancer Cell Subtyping
Advanced Science, EarlyView.This study presents a dual‐mode imaging platform that utilizes self‐assembly and disassembly of DNA scaffolds for high‐resolution cancer cell detection. The structural rigidity of DNA scaffolds effectively prevents cellular internalization for over 300 min.
Xiaolin Hu +15 more
wiley +1 more source
Redox Biology, 2019 Treatment of tumor cells with H2O2 and nitrite, two long-lived species derived from cold atmospheric plasma, induces a complex autoamplificatory, singlet oxygen-mediated process, which leads to catalase inactivation and reactivation of intercellular ...
Georg Bauer
doaj +1 more source
Understanding Self-Reported Sexual Violence Perpetration: Correlates and Prevention Participation [PDF]
, 2018 Bystander prevention programs seek to educate individuals on the nature of sexual violence and increase bystander efficacy. This study seeks to evaluate the effectiveness of the Bringing in the Bystander (BITB) prevention program through self-reports of ...
Klatt, Jacqueline F.
core +1 more source
Advanced Science, EarlyView.IR‐induced dysbiosis depletes P. coprophilus and its metabolite 6‐methyluracil, leading to disinhibition of the IDO1‐Kyn‐AHR axis. This results in sustained fibroblast activation and collagen deposition, driving radiation induced intestinal fibrosis. ABSTRACT Therapeutic options for radiation‐induced intestinal fibrosis (RIF) remain limited. This study
Jiaxin Zhang +11 more
wiley +1 more source