Results 131 to 140 of about 73,132 (261)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Ảnh hưởng của mỡ cá Tra trong khẩu phần lên năng suất , chất lượng trứng và khối lượng loại thải gà mái Hisex Brown nuôi công nghiệp

Tạp chí Khoa học Đại học Cần Thơ, 2015
Thí nghiệm được tiến hành để đánh giá ảnh hưởng của mỡ cá tra lên năng suất, chất lượng trứng và khối lượng loại thải gà mái Hisex Brown giai đoạn 62-72 tuần tuổi, trước khi loại thải gà mái nuôi công nghiệp.
Nguyễn Thị Thủy, Huynh Minh Quan
doaj  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

NGHIÊN CỨU ỨNG DỤNG QUI TRÌNH PCR CHẨN ĐOÁN VI KHUẨN AEROMONAS HYDROPHILA TRÊN THẬN CÁ TRA (PANGASIANODON HYPOPHTHALMUS)

Tạp chí Khoa học Đại học Cần Thơ, 2010
Qui trình PCR phát hiện vi khuẩn Aeromonas hydrophila nhiễm trên thận cá tra (Pangasianodon hypophthalmus) được thực hiện và chuẩn hóa. Trong qui trình này mồi xuôi AeroFd và mồi ngược AeroRs được sử dụng để khuếch đại gen Aerolysin của A. hydrophila với
Nguyễn Hà Giang, Lê Hữu Thôi, Trương Quỳnh Như, Đặng Thị Hoàng Oanh   +3 more
doaj  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Feasibility and Safety of Transradial Approach with 8-French Balloon Guide Catheter for Carotid Artery Stenting: Case Series. [PDF]

J Neuroendovasc Ther
Kojima D, Shimada Y, Miyoshi K, Setta K, Kashimura H, Akamatsu Y.   +5 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Usefulness of the minimally invasive flow reversal method in carotid artery stenting: Simplified flow reversal carotid artery revascularization for radial access (SF-CARR). [PDF]

Interv Neuroradiol
Kayahara T, Shozuhara N, Fukumoto K, Kido S, Tsukagoshi E, Matsumoto T, Nakagami T, Yoshimura M, Kohyama S.   +8 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source