Results 171 to 180 of about 713,196 (235)

Temporal Response Function-Driven Representational Similarity Analysis for Speech Perception Decoding with MEG and EEG. [PDF]

Biology (Basel)
Liu C, Guo Y, Ding J, Li L, Ma Y, Ning X.   +5 more
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Efficacy and Safety of Intravenous Paracetamol Compared With Intramuscular Tramadol for Labour Analgesia: A Randomised Comparative Study. [PDF]

Cureus
Nandi M, Mondal P, Mondal R.
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Effect of prior anti-EGFR therapy and baseline ctDNA profiling on the efficacy of pertuzumab plus trastuzumab in HER2-amplified metastatic colorectal cancer: an integrated analysis of TRIUMPH/MyPathway. [PDF]

ESMO Open
Matsubara Y, Wakabayashi M, Okamoto W, Kato T, Esaki T, Kato K, Komatsu Y, Masuishi T, Nishina T, Bando H, Misumi T, Fukui M, Matsuda S, Ikeda Y, Malato J, Schulze K, Price R, Sato A, Yoshino T, Nakamura Y.   +19 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Wastewater-based assessment of episodic changes in psychoactive compounds and hormones during music festivals. [PDF]

Environ Monit Assess
Tulipánová A, Mackuľak T, Horáková I, Imreová Z, Drdanová AP, Bořík A, Šauer P, Kroupová HK, Grabic R, Bímová P, Staňová AV.   +10 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Shared T -Cell Receptor Repertoire in the Tonsils of Patients with IgA Nephropathy. [PDF]

Kidney360
Satokata K, Goto S, Goto S, Yamaguchi H, Watanabe H, Takahashi N, Higashi K, Yamamoto S, Kaneko Y, Horii A, Kurokawa K, Narita I.   +11 more
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source