Results 121 to 130 of about 3,814,564 (336)

Carcinoma de cérvix uterino localmente avanzado Presentación de un caso clínico [PDF]

, 2016
El cáncer de cuello uterino supone el 4.5% de las neoplasias malignas de la mujer. El principal factor de riesgo relacionado es la infección genital por el virus del papiloma humano (VPH).
Osorio Aira, Sonia
core  

Adolescencia y cáncer [PDF]

, 2015
Adolescence covers from the 15 to the 19 years of age, is a period of transition in the development from childhood to adult life. The appearance of youth changes as a result of the hormonal events of puberty.
Bellver Pérez, Ascensión, Verdet Martínez, Helade   +1 more
core   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

A case report: Giant early gastric cancer [PDF]

, 2017
Indexación: Scopus; Scielo.Introducción: El cáncer gástrico es la primera causa de muerte por cáncer, en hombres, en Chile, siendo el adenocarcinoma la variante más frecuente.
Carrasco A., G., Pérez C., A., Vidal A., N.   +2 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Diseño y métodos de un estudio de la historia natural de la neoplasia de cuello uterino en la población de una provincia rural de Costa Rica: el Proyecto de Guanacaste

Revista Panamericana de Salud Pública
En este documento se informa sobre la fase de inscripción de un estudio de la historia natural de la neoplasia de cuello uterino basado en la población de Guanacaste, una provincia rural de Costa Rica con tasas constantemente elevadas de cáncer ...
Rolando Herrero, Mark H. Schiffman, Concepción Bratti, Allan Hildesheim, Ileana Balmaceda, Mark E. Sherman, Mitchell Greenberg, Fernando Cárdenas, Víctor Gómez, Kay Helgesen, Jorge Morales, Martha Hutchinson, Laurie Mango, Mario Alfaro, Nancy W. Potischman, Sholom Wacholder, Christine Swanson, Louise A. Brinton   +17 more
doaj   +1 more source

The kinesin spindle protein inhibitor filanesib enhances the activity of pomalidomide and dexamethasone in multiple myeloma

Haematologica, 2017
Kinesin spindle protein inhibition is known to be an effective therapeutic approach in several malignancies. Filanesib (ARRY-520), an inhibitor of this protein, has demonstrated activity in heavily pre-treated multiple myeloma patients.
Susana Hernández-García, Laura San-Segundo, Lorena González-Méndez, Luis A. Corchete, Irena Misiewicz-Krzeminska, Montserrat Martín-Sánchez, Ana-Alicia López-Iglesias, Esperanza Macarena Algarín, Pedro Mogollón, Andrea Díaz-Tejedor, Teresa Paíno, Brian Tunquist, María-Victoria Mateos, Norma C Gutiérrez, Elena Díaz-Rodriguez, Mercedes Garayoa, Enrique M Ocio   +16 more
doaj   +1 more source

Cáncer Bucal [PDF]

, 2008
El Cáncer bucal y bucofaríngeo representa el 3% de todos los canceres, sin embargo, son de los que menor tasa de sobre vida a 5 años presentan. Los canceres bucales son diagnosticados en estadios avanzados en un 68-72% de los casos, lo cual en muchas ...
Alemán Navas, Ramón Manuel, Martinez Mendoza, Maria Guadalupe, Sandoval, Luis   +2 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Cáncer colorrectal hereditario: presentación sincrónica de cáncer colorrectal y colangiocarcinoma en un paciente con poliposis adenomatosa familiar [PDF]

, 2020
A.F. Chapa-Lobo, L.E. Salgado-Cruz, Alan Alejandro Garza-Cantú, Mauricio David Castaño-Eguía, Fernando Rodríguez-Sotelo, Roy Ismael Villafranca-Andino   +5 more
openalex   +1 more source