Results 41 to 50 of about 213,956 (190)

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

FEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez, Cristina Velez‐delValle, Claudia Patricia Hernández‐Mosqueira, Walid Kuri‐Harcuch   +3 more
wiley   +1 more source

Modelos celulares de cáncer de próstata [PDF]

, 2008
Modelos celulares de cáncer de próstata. Líneas celulares, PC-3/S-luc y PC-3/M-luc, derivadas de la línea de cáncer de próstata PC-3, modificadas de forma que expresan el gen luciferasa (luc) para el desarrollo de un modelo de cáncer, útil para el ...
Blanco, Jerónimo, Celià-Terrassa, Toni, Meca-Cortés, Óscar, Rubio, Nuria, Thomson, Timothy M., Vilalta Colomer, Marta   +5 more
core  

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

FEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring, Morten Roedgaard, Camilla Myrup Holst, Helene Christensen, Birgitta R. Knudsen, Lotte Bjergbaek, Anni Hangaard Andersen   +6 more
wiley   +1 more source

Epidemiología del cáncer en Andalucía entre 2001 y 2011 [PDF]

, 2013
Se trata de un trabajo en el que se pretende describir la mortalidad por cáncer en Andalucía y en nuestra provincia, entre los años 2001-2011 para conocer la magnitud del problema, y explicar los factores de riesgo asociados al cáncer y proponer medidas ...
Cruz Aguilar, Mª Teresa
core   +1 more source

Wearable activity technology and action-planning (WATAAP) to promote physical activity in cancer survivors: Randomised controlled trial protocol [PDF]

, 2018
Background/Objective: Colorectal and gynecologic cancer survivors are at cardiovascular risk due to comorbidities and sedentary behaviour, warranting a feasible intervention to increase physical activity.
Cohen, Paul A, Hardcastle, Sarah J, Hince, Dana A, Jimenez-Castuera, Ruth, Kane, Robert T, Levitt, Michael, Makin, Gregory B, Maxwell-Smith, Chloe, Mohan, Ganendra Raj Kader Ali, Platell, Cameron, Salama, Paul, Salfinger, Stuart, Tan, Jason, Tan, Patrick   +13 more
core   +2 more sources

Cáncer de seno en la Clínica San Pedro Claver de Bogotá, 2004 [PDF]

Revista de Salud Pública, 2006
Reviewing new cases of breast cancer attending Clinica San Pedro Claver, Bogotá, Colombia, during 2004.Patients were recruited from the meeting offered by the service which all new breast cancer patients attend. Hospitalised patients, outpatients, clinical meetings, consulting rooms, operating room schedules and pathology reports were consulted to ...
openaire   +4 more sources

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

Cáncer hereditario y consejo genético [PDF]

, 2016
El término cáncer engloba múltiples enfermedades, todas ellas caracterizadas por el crecimiento y división descontrolada de células a partir de poblaciones celulares mutadas.
Borge Olmedo, Sara
core   +2 more sources

Frecuencia y distribucion de cancer oral en el Hospital Regional de Talca y Hospital Base de Curico entre los años 1991 y 1992 [PDF]

, 2003
96 p.Se realizó un estudio descriptivo de cáncer oral en el Hospital Regional de Talca y Hospital Base de Curico entre los anos 1991 a 2002.
Melendez Meza, Marcela Paz, Venegas Rojas, Bernardo (Prof. Guia)   +1 more
core  

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source