Results 51 to 60 of about 3,946,056 (287)

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Analysis of external personal dosimetry for external ex-posure to medical radiation workers in radiotherapy and nuclear medicine departments between 2019 and 2022

Brazilian Journal of Radiation Sciences
The National Cancer Institute from Chile possesses a wide variety of high-complexity equipment for cancer treatment and diagnosis that employs ionizing radiation with high and medium energy.
M. C. Mancilla, A. Ferreira-Tapia, L. M. Ayala   +2 more
doaj   +1 more source

Metástasis cutánea en cáncer de estómago en Perú y revisión de literatura

Gaceta Mexicana de Oncolog�a, 2023
Las neoplasias malignas del tracto gastrointestinal tienen el potencial de metástasis en la piel, pero el adenocarcinoma gástrico es bastante raro que presente metástasis cutánea. Puede ser el primer signo de etapa avanzada, además de ser un signo de recurrencia después del tratamiento.
openaire   +2 more sources

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

The role of m6A, m5C and Ψ RNA modifications in cancer: Novel therapeutic opportunities

Molecular Cancer, 2021
RNA modifications have recently emerged as critical posttranscriptional regulators of gene expression programmes. Significant advances have been made in understanding the functional role of RNA modifications in regulating coding and non-coding RNA ...
Paz Nombela, Borja Miguel-López, Sandra Blanco   +2 more
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

VAV2 orchestrates the interplay between regenerative proliferation and ribogenesis in both keratinocytes and oral squamous cell carcinoma

Scientific Reports
VAV2 is an activator of RHO GTPases that promotes and maintains regenerative proliferation-like states in normal keratinocytes and oral squamous cell carcinoma (OSCC) cells. Here, we demonstrate that VAV2 also regulates ribosome biogenesis in those cells,
Natalia Fernández-Parejo, L. Francisco Lorenzo-Martín, Juana M. García-Pedrero, Juan P. Rodrigo, Mercedes Dosil, Xosé R. Bustelo   +5 more
doaj   +1 more source

An unexpected tumor suppressor role for VAV1a

Molecular & Cellular Oncology, 2018
RHO GDP/GTP exchange factors, including VAV1, are considered key protumorigenic factors. Against this paradigm, we have found that VAV1 plays tumor suppressor roles by buffering NOTCH1 signals in thymocytes.
Xosé R. Bustelo, L. Francisco Lorenzo-Martín, Myriam Cuadrado, Isabel Fernández-Pisonero, Javier Robles-Valero   +4 more
doaj   +1 more source

Regulation of cytokine signaling through direct interaction between cytokine receptors and the ATG16L1 WD40 domain

Nature Communications, 2020
The WD40 domain of ATG16L1 is thought to be involved in non-canonical autophagy. Here the authors screen peptide libraries and identify interactions between this domain and the IL-2Rγ and IL-10RB receptors, indicating endosomal regulation of cytokine ...
Inmaculada Serramito-Gómez, Emilio Boada-Romero, Raquel Villamuera, Álvaro Fernández-Cabrera, José Luis Cedillo, Ángela Martín-Regalado, Simon Carding, Uli Mayer, Penny P. Powell, Thomas Wileman, Irene García-Higuera, Felipe X. Pimentel-Muiños   +11 more
doaj   +1 more source

PREVENÇÃO DO CÂNCER DE COLO UTERINO: O PRESÍDIO COMO UM ESPAÇO PROMOTOR DE SAÚDE

Revista Eletronica Gestão & Saúde, 2013
A mulher reclusa constitui uma população vulnerável para a não realização do exame preventivo e, desta forma, para o câncer cervical. Trata-se de um relato de experiência acerca de uma estratégia educativa aplicada em um presídio feminino de Fortaleza. A intervenção educativa foi realizada com um total de 25 participantes.
Vasconcelos, Camila Teixeira Moreira, Coelho, Cássia Fernandes, Cunha, Denise de Fátima Fernandes, Aquino, Priscila de Souza, dos Anjos, Saiwori de Jesus Silva Bezerra, Pinheiro, Ana Karina Bezerra   +5 more
openaire   +2 more sources