ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source
Caracterización del ciclo menstrual en un grupo de mujeres con Cancer de mama del Centro Oncolologico ISSEMYM, Toluca, Estado de Mexico [PDF]
Uno de los problemas de salud con mayor impacto económico y social es el cáncer de mama, es la principal neoplasia que presenta la población mexicana en edad reproductiva. Es importante destacar que hasta hoy en día, las estrategias para la detección
Aguilar Juarez, Neltzi Anayeli +1 more
core
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman +8 more
wiley +1 more source
Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul +13 more
wiley +1 more source
Análisis del impacto de medidas complementarias en la calidad de vida de pacientes con cáncer de mama [PDF]
[ES] El cáncer de mama es el segundo cáncer más frecuente en el mundo y el primero con diferencia si solo se tiene en cuenta el sexo femenino. Según los datos proporcionados por el proyecto GLOBOCAN de la Organización Mundial de la Salud (OMS) se estima ...
Martín Prieto, Jon
core
Lewis X antigen mediates adhesion of human breast carcinoma cells to activated endothelium. Possible involvement of the endothelial scavenger receptor C-Type lectin [PDF]
Lewis x (Lex, CD15), also known as SSEA-1 (stage specific embryonic antigen-1), is a trisaccharide with the structure Galβ(1–4)Fucα(1–3)GlcNAc, which is expressed on glycoconjugates in human polymorphonuclear granulocytes and various tumors such as colon
A Hittelet +51 more
core +1 more source
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior +7 more
wiley +1 more source
Prevalence and Trajectory of Household Material Hardship Among Children With Advanced Cancer
ABSTRACT Background/Objectives Families of children with advanced cancer living in poverty experience inferior outcomes including poor parent mental health and worse child quality of life. Household material hardship (HMH: food, housing, transportation, and/or utility insecurity) is a modifiable poverty exposure—and potential intervention target—that ...
Sarah Wright +13 more
wiley +1 more source
Cáncer de Cuello de Útero: estrategias de Prevención [PDF]
Introducción: El cáncer de cérvix es el tercer cáncer más frecuente en la población femenina; y es considerado una secuela a largo plazo de la infección persistente del Virus del Papiloma Humano, su principal factor etiológico.
Gutiérrez Sainz de Aja, Elena
core
MAP17 predicts sensitivity to platinum-based therapy, EGFR inhibitors and the proteasome inhibitor bortezomib in lung adenocarcinoma [PDF]
Background The high incidence and mortality of lung tumours is a major health problem. Therefore, the identification both of biomarkers predicting efficacy for therapies in use and of novel efficacious therapeutic agents is crucial to increase patient ...
Carnero Moya, Amancio +5 more
core +1 more source

