Results 81 to 90 of about 3,678,468 (242)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Perfil sociodemográfico e clínico de mulheres com câncer do colo do útero em uma cidade do Nordeste
Revista Eletronica Gestão & Saúde, 2015 RESUMO OBJETIVO: Descrever o perfil sociodemográfico e clínico das mulheres com câncer do colo do útero na cidade de Teresina. METODOLOGIA: Estudo epidemiológico, descritivo, transversal e retrospectivo, de abordagem quantitativa com dados coletados na base de dados de um hospital filantrópico de referencia em oncologia para os municípios do Piauí e ...
Ribeiro, José Francisco +4 more
openaire +5 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Combined HRAS and NRAS ablation induces a RASopathy phenotype in mice
Cell Communication and SignalingBackground HRASKO/NRASKO double knockout mice exhibit exceedingly high rates of perinatal lethality due to respiratory failure caused by a significant lung maturation delay.
Rocío Fuentes-Mateos +8 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Infectious Agents and Cancer, 2019 In the original publication of this article [1] several figures and tables were incorrectly displayed. In this correction article the correct overview of the tables and figures are published. The original article has been updated.
José Revilla-López +13 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Cancer cases detected in the prevention and control service of a private cancer clinic in Peru
Infectious Agents and Cancer, 2019 Purpose Describe the characteristics of patients seen at the Cancer Prevention and Control Service at a Peruvian private cancer clinic in 2014.
José Revilla-López +13 more
doaj +1 more source