Results 21 to 30 of about 355,520 (263)

“CONCORDANCIA CITOLÓGICA, HISTOLÓGICA Y COLPOSCÓPICA EN EL DIAGNÓSTICO DE LESIÓN INTRAEPITELIAL CERVICAL Y FACTORES DE RIESGO ASOCIADOS EN EL HOSPITAL GENERAL DE NAUCALPAN DEL 2008 AL 2011” [PDF]

, 2013
El cáncer de cérvix es resultado de un proceso, la mayoría de las veces gradual y de lenta evolución, que inicia con lesiones precursoras asociadas a otros factores de riesgo.
Frias Flores, Víctor Manuel, García López, Antonio   +1 more
core  

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Cervical cancer screening by cytology and the burden of epithelial abnormalities in low resource settings: a tertiary-center 42-year study

BMC Women's Health
Background Cytological screening remains a high-impact practice, particularly in low-resource settings, for preventing cervical cancer. The examination of screening practices over time and the prevalence of epithelial abnormalities have not been ...
Sahar Ezzelarab, Amro El-Husseiny, Magda Nasreldin, Radwa Ali, Ashraf Nabhan, Early Cervical Cancer Detection Consortium   +5 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Factores de riesgos en mujeres diagnosticadas con lesiones pre malignas de cuello uterino a través de PAP, atendidas en el Hospital José Nieborowski, Boaco. Enero 2013-diciembre 2014 [PDF]

, 2015
Con el objetivo de conocer la frecuencia de factores de riesgo en mujeres diagnosticadas con lesiones pre malignas de cuello uterino a través de PAP, atendidas en el Hospital José Nieborowski, Boaco entre enero 2013 y diciembre 2014, se llevó un estudio ...
Henríquez, Handrea María, Ortega Bonilla, Raúl Salvador   +1 more
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

“CORRELACIÓN CITO-HISTOLÓGICA DE LESIONES INTRAEPITELIALES ESCAMOSAS CERVICALES DE BAJO Y ALTO GRADO CON INFECCIÓN POR VIRUS DEL PAPILOMA HUMANO EN PACIENTES QUE ACUDEN A LA CLINICA DE DISPLASIAS DEL HOSPITAL MATERNO INFANTIL ISSEMYM EN EL PERIODO COMPRENDIDO DEL 01 DE ENERO DEL 2012 AL 31 DE OCTUBRE DEL 2012”. [PDF]

, 2013
En la literatura revisada, la correlación cito-histológica tuvo coincidencias totales del 66.9% y discrepancias menores del 18,6%. Las discrepancias mayores fueron de subdiagnóstico citológico del 46.3% y sobrediagnóstico del 50%
Giles Fierro, René, Ortega Ruíz, Anahí Minne   +1 more
core  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Cáncer cervico uterino [PDF]

, 2016
Las enfermedades no trasmisibles son enfermedades de larga duración y, por lo general, de progresión lenta. Los datos científicos actuales indican que cuatro tipos de enfermedades no transmisibles (enfermedades cardiovasculares, cánceres, enfermedades ...
Avilés Téllez, Adán Eduardo, Mercado Roiz, Vielka Jahaira   +1 more
core