Results 21 to 30 of about 349,369 (245)

Cervical cancer screening by cytology and the burden of epithelial abnormalities in low resource settings: a tertiary-center 42-year study

open access: yesBMC Women's Health
Background Cytological screening remains a high-impact practice, particularly in low-resource settings, for preventing cervical cancer. The examination of screening practices over time and the prevalence of epithelial abnormalities have not been ...
Sahar Ezzelarab   +5 more
doaj   +1 more source

FRECUENCIA DE INFECCIONES POR VPH Y DISPLASIA CERVICAL Y FACTORES DE RIESGO ASOCIADOS, EN LAS UNIDADES CSRD SANTA ANA MAYORAZGO Y PILAR MARIA, OTZOLOTEPEC, MÉXICO EN EL PERIÓDO 01 AGOSTO DEL 2013 AL 28 DE FEBRERO DEL 2014. [PDF]

open access: yes, 2014
La persistencia de virus de papiloma humano de alto riesgo oncog̩nico ha sido identificada como un importante factor etológico en el desarrollo de displasia cervical.
Barranco Cuadros, Eder   +2 more
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Factores de riesgos en mujeres diagnosticadas con lesiones pre malignas de cuello uterino a través de PAP, atendidas en el Hospital José Nieborowski, Boaco. Enero 2013-diciembre 2014 [PDF]

open access: yes, 2015
Con el objetivo de conocer la frecuencia de factores de riesgo en mujeres diagnosticadas con lesiones pre malignas de cuello uterino a través de PAP, atendidas en el Hospital José Nieborowski, Boaco entre enero 2013 y diciembre 2014, se llevó un estudio ...
Henríquez, Handrea María   +1 more
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Prevalencia del virus del papiloma humano en mujeres de un cribado poblacional [PDF]

open access: yes, 2017
El virus del papiloma humano (VPH), es causa necesaria para que una mujer desarrolle cáncer de cuello uterino. El objetivo del estudio es estimar la prevalencia, de mujeres con infección de VPH, pertenecientes al programa de prevención y detección ...
Suárez del Fueyo, Gabriel
core  

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Cáncer cervico uterino [PDF]

open access: yes, 2016
Las enfermedades no trasmisibles son enfermedades de larga duración y, por lo general, de progresión lenta. Los datos científicos actuales indican que cuatro tipos de enfermedades no transmisibles (enfermedades cardiovasculares, cánceres, enfermedades ...
Avilés Téllez, Adán Eduardo   +1 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Discovery of key genes as novel biomarkers specifically associated with HPV-negative cervical cancer

open access: yesMolecular Therapy: Methods & Clinical Development, 2021
Cervical cancer is a common female malignancy that is mainly caused by human papillomavirus (HPV) infection. However, the incidence of HPV-negative cervical cancer has shown an increasing trend in recent years.
Yi Liu   +5 more
doaj   +1 more source

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