Results 1 to 10 of about 262,254 (163)

Human Papillomavirus E7 and p16^INK4a mRNA Multiplexed Quantification by a QuantiGene^TM Proof-of-Concept Assay Sensitively Detects Infection and Cervical Dysplasia Severity

Diagnostics, 2023
Background: Persistent infection with human papillomavirus (HPV) can lead to cervical cancer (CxCa). During the progression to CxCa, the expression of HPV oncogenes E6 and E7 is upregulated. In turn, cellular proteins such as p16INK4a are also modulated.
Anna Sophie Skof, Lina Rotenberg, Paul Viktor Felix Hannemann, Sarah Thies, Eleonora Boschetti-Grützmacher, Andreas M. Kaufmann   +5 more
doaj   +1 more source

Enhancement of specific T-lymphocyte responses by monocyte-derived dendritic cells pulsed with E2 protein of human papillomavirus 16 and human p16INK4A [PDF]

PeerJ, 2020
Introduction Prophylactic vaccines are already available for prevention of human papillomavirus (HPV) infection. However, we still await development of therapeutic vaccines with high efficiency for stimulating specific T lymphocytes to clear HPV ...
Nuchsupha Sunthamala, Neeranuch Sankla, Jureeporn Chuerduangphui, Piyawut Swangphon, Wanchareeporn Boontun, Supakpong Ngaochaiyaphum, Weerayut Wongjampa, Tipaya Ekalaksananan, Chamsai Pientong   +8 more
doaj   +2 more sources

TLR9 and Glioma: Friends or Foes?

Cells, 2022
Toll-like receptor 9 (TLR9) is an intracellular innate immunity receptor that plays a vital role in chronic inflammation and in recognizing pathogenic and self-DNA in immune complexes. This activation of intracellular signaling leads to the transcription
Emna Fehri, Emna Ennaifer, Rahima Bel Haj Rhouma, Monia Ardhaoui, Samir Boubaker   +4 more
doaj   +1 more source

The recovery strategies to support cervical cancer elimination in lower-and middle-income countries (LMICs) following COVID-19 disruptions

Preventive Medicine Reports, 2023
The COVID-19 pandemic has exacerbated the existing challenges to achieving the WHO target of eliminating cervical cancer as a public health problem by working towards the target of fewer than four cases per 100 000 women.
Jieying Lee, Ida Ismail-Pratt, Dorothy A Machalek, Suresh Kumarasamy, Suzanne M. Garland   +4 more
doaj   +1 more source

Detection and genotyping of human Papillomavirus in urine samples from unvaccinated male and female adolescents in Italy [PDF]

, 2013
The introduction of vaccination against Human Papillomavirus (HPV) in adolescent girls in 2006 has focused virological surveillance on this age group. As few studies have evaluated HPV infections in young populations, further data are needed in order to ...
Amicizia, Daniela, Bianchi, Silvia, Boccalini, Sara, Bonanni, Paolo, Castiglia, Paolo Giuseppino, Coppola, Rosa Cristina, Frati, Elena Rosanna, Gasparini, Roberto, Martinelli, Marianna, Martinese, Morena, Masia, Giuseppina, Meloni, Angelo, Panatto, Donatella, Piana, Andrea Fausto, Tanzi, Elisabetta, Zotti, Carla Maria   +15 more
core   +10 more sources

Detection of HPV in cancerous and non-cancerous esophageal tissues from Turkmen-Sahra, Iran [PDF]

, 2006
The aim of this study were to assess the presence of HPV esophageal infection among Iranian Turkmen who live in an area located in the cancer belt in Asia. The specimens derived from 120 patients previously diagnosed for Squamous Cell Carcinoma (SCC) non-
Mokhtari-Azad, T., Moradi, A.
core   +1 more source

Hemorragia Alveolar Difusa - a propósito de um caso clínico de Hemossiderose Pulmonar Idiopática.

Revista Portuguesa de Pneumologia, 1999
RESUMO: Devido à sua raridade, a Hemorragia Alveolar Difusa (HAD) é muitas vezes urn diagnóstico esquecido. Os autores apresentam uma revisião desta entidade a propósito do caso clínico de um homem de 71 anos, internado por febre, tosse seu ...
Paula Esteves, Luís Telo, Filipe Froes, Leonardo Ferreira, Cecìlia Nunes, Paula Duarte, Raul Amaral-Marques   +6 more
doaj   +1 more source

Influence of resuspension volume on dry sampling devices taken for human papillomavirus testing: implications for self-sampling

BioTechniques, 2023
Optimization of technical parameters that influence the performance of human papillomavirus (HPV) testing on self-taken samples is important. Here, the authors assessed the impact of resuspension volume on the detection of HPV using four validated HPV ...
Linzi Connor, Hana Elasifer, Alex Sargent, Ramya Bhatia, Catriona Graham, Kate Cuschieri   +5 more
doaj   +1 more source

Frequent detection of high human papillomavirus DNA loads in oral potentially malignant disorders [PDF]

, 2016
Human papillomavirus (HPV) is estimated to be the cause of 40-80% of the squamous cell carcinoma of the oropharynx but only of a small fraction of the oral cavity cancers.
ANTONELLI, Guido, CANNELLA, FABIANA, Ciolfi, Chiara, GENTILE, Massimo, PALAIA, GASPARE, PIERANGELI, Alessandra, POLIMENI, Antonella, ROMEO, Umberto, RUSSO, CLAUDIA, SCAGNOLARI, CAROLINA, SCIANDRA, ILARIA   +10 more
core   +1 more source

Poliserosite

Revista Portuguesa de Pneumologia, 1999
RESUMO: No presente caso clínico descreve-se um doente com poliserosite, trombocitopénia autoimune e artrite não erosiva. Apresenta ainda lesões cutâneas sugestivas, mas não suficientemente expressivas para a sua inclusão nos critérios de Lupus ...
Carlos Boinas, José Albergaria Ambar, Casimiro Machado, Maria João Marques Gomes   +3 more
doaj   +1 more source