Results 41 to 50 of about 192,544 (305)

A plant protein signal sequence improved humoral immune response to HPV prophylactic and therapeutic DNA vaccines

Human Vaccines & Immunotherapeutics, 2017
Signal sequences (ss) play a critical role in the sorting of nascent secretory and membrane proteins. This function has been conserved from bacteria through eukaryotes, although ss appear diverse in length and amino acid composition.
Silvia Massa, Francesca Paolini, Gianfranca Curzio, Marcelo Nazario Cordeiro, Elena Illiano, Olivia Costantina Demurtas, Rosella Franconi, Aldo Venuti   +7 more
doaj   +1 more source

Long-term effectiveness of the nine-valent human papillomavirus vaccine in Scandinavian women: interim analysis after 8 years of follow-up

Human Vaccines & Immunotherapeutics, 2021
A long-term follow-up (LTFU) of the nine-valent human papillomavirus (9vHPV) vaccine efficacy study in young women aged 16–26 years was initiated to evaluate if vaccine effectiveness for up to 14 years post-vaccination will remain above 90%.
Susanne K. Kjaer, Mari Nygård, Karin Sundström, Christian Munk, Sophie Berger, Mensur Dzabic, Katrin Elisabeth Fridrich, Marianne Waldstrøm, Sveinung Wergeland Sørbye, Oliver Bautista, Thomas Group, Alain Luxembourg   +11 more
doaj   +1 more source

Importância da avaliação funcional do controle da ventilação** Apresentada no curso satéllite da Reunião da SPP em Counbra

Revista Portuguesa de Pneumologia, 1999
RESUMO: Estudamos o controle da respiração com a finalidade primordial de avaliar a dispneia. A presente abordagem deve ser feita a vários niveis, uma vez que o centro respiratório pode estar integro mas os efectores a nivel dos circuitos neuronais podan
Miguel Mota Carmo, Cristina Barbara, Teresa Ferreira, Sara Ferreira, Rita Ferreira, Antonio Rendas   +5 more
doaj   +1 more source

A comprehensive HPV-STI NGS assay for detection of 29 HPV types and 14 non-HPV sexually transmitted infections

Infectious Agents and Cancer, 2022
Background Sexually transmitted infections (STIs) are prevalent throughout the world and impose a significant burden on individual health and public health systems.
Zhihai Ma, Baback Gharizadeh, Xingsheng Cai, Mengzhen Li, María Dolores Fellner, Jorge Alejandro Basiletti, Rita Mariel Correa, María Celeste Colucci, Gabriela Baldoni, Martín Vacchino, Patricia Galarza, María Alejandra Picconi, Chunlin Wang   +12 more
doaj   +1 more source

Prevalence and risk factors for oral human papillomavirus and Epstein-Barr virus co-infections among sexually active males and females in Ibadan, Nigeria

BMC Oral Health
Background Co-infection of Human papillomavirus (HPV) and Epstein–Barr virus (EBV) is associated with oral and oropharyngeal cancers. This study examined the prevalence and associated risk factors for oral HPV and EBV co-infection among sexually active ...
Adeola Fowotade, Deborah Oke, Yusuf Bello, Adekunle Daniel, Akinyele Adisa, Moses Adewumi, Margaret Okoeguale, Olasunkanmi Olisa, Yinan Zheng, Deborah Watson-Jones, Isaac Adewole, Robert Murphy, Lifang Hou, Imran O. Morhason-Bello   +13 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Cell cycle control and its modulation in HPV infected cells [PDF]

, 2010
A key effect of human papillomavirus (HPV) infection is to disrupt the normal cell cycle in order to subvert the cellular DNA replication machinery. Morphologically, condylomata induced by high and low risk HPV types cannot be distinguished and many ...
Lyman, Rachel C.
core   +2 more sources

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Patterns of blood pressure and factors associated with hypertension among young adults in Ibadan, Nigeria

BMC Cardiovascular Disorders
Background Hypertension is increasingly recognised among younger adults and contributes to early cardiovascular risk, yet population-level data in this age group remain limited in many low- and middle-income countries. This study examined the patterns of
Deborah Oke, Okechukwu Ogah, Yusuf Bello, Oluwatosin Lawal, Yusuf Kareem, Ololade Adeyemi, Oluwatoyin Olalemi, Babatunde Adedokun, Babatunde Salako, Isaac Adewole, Deborah Watson-Jones, Imran Morhason-Bello   +11 more
doaj   +1 more source

Access to HPV vaccination for boys in the United Kingdom

Medicine Access @ Point of Care, 2018
Human papillomavirus (HPV) is a common sexually transmitted infection. There is a well-established link between HPV and the development of cervical cancer, but HPV infection is also associated with vaginal and vulvar cancer, head and neck cancers as well
Gillian Prue, David Grimes, Peter Baker, Mark Lawler   +3 more
doaj   +1 more source