Results 61 to 70 of about 74,023 (261)

HER2 and HER3 in HPV+ and HPV− HNSCC—Letter

Clinical Cancer Research, 2016
The nice experiments performed by Pollock and colleagues showed that Human papillomavirus (HPV) infection coincided with overexpression of HER2 (ERBB2), HER3 (ERBB3), and the associated HER2:HER3 heterodimer and that this may contribute to EGFR therapy resistance.
Machiels, Jean-Pascal, Galot, Rachel, Schmitz, Sandra   +2 more
openaire   +3 more sources

Detecção molecular do DNA e RNAm do HPV e sua aplicabilidade na triagem do câncer cervical [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2011O câncer de colo uterino representa o segundo tipo de câncer mais comum entre as mulheres.
Martins, Toni Ricardo
core  

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Factores de Crescimento Hematopoiético

Revista Portuguesa de Pneumologia, 1995
SUMÁRIO: Os factores de crescimento hematopoiético (FCH) são glicoproteinas que regulam a proliferação e diferenciação das células sanguíneas.
Maria De Fátima Miguel Rodrigues, Margarida Cristóvão, Agostinho Costa, M.a José Melo   +3 more
doaj   +1 more source

Noninvasive Characterization of Tumor Heterogeneity in HNSCC: From Clinical Utility to Biological Correlates

Advanced Science, EarlyView.
This study establishes a CT‐based radiomics framework to quantify intratumoral heterogeneity (ITH) in HNSCC. Using unsupervised clustering, tumor ROIs and VOIs are analyzed to calculate 2D/3D ITH scores. The score shows strong predictive value for prognosis and immunotherapy response, and is associated with tumor metabolism and immune microenvironment,
Xinwei Chen, Rui Liu, Yuan Zhou, Yin Xiao, Chengmin Feng, Lin Chen, Yanshi Li, Mengna Wang, Zhaobo Cheng, Yuxi Luo, Long Liu, Lijing Niu, Yue Xiang, Juan Peng, Guohua Hu, Min Pan   +15 more
wiley   +1 more source

Nucleic Acid Therapeutics for “Undruggable” Cancer Targets: Mechanisms, Challenges, and Prospects

Advanced Science, EarlyView.
Nucleic acid therapeutics bypass the structural limitations of conventional drugs by targeting mRNA rather than proteins. This review examines how antisense oligonucleotides, siRNAs, miRNAs, aptamers, and mRNA vaccines intervene against historically undruggable oncoproteins including Ras, MYC, and p53, highlighting mechanistic advances, delivery ...
Feng Xu, Ke Wang, Kaizhong Lu, Tianlun Hou, Yuan Chen, Xian Wang, Hongchuan Jin   +6 more
wiley   +1 more source

Genotype distribution and molecular characterization of HPV in the Peruvian amazon: insights into prevalence, lineage diversity, and viral integration

Scientific Reports
Cervical cancer remains a leading cause of cancer-related mortality among women in Peru, with the highest death rates reported in the Amazon region. Despite this burden, molecular data on human papillomavirus (HPV) in this area are limited.
Lesly Solis-Ponce, Milan Stosic, Greisi Curicó, Susan Espetia, Heidy Sanchez-Grandez, Sadaf Sakina Hassan, Jorge Basiletti, Kristiane Søreng, Maribel Acuña-Barrios, Lilian Huarca-Balbin, Mariela Yaya-Ríos, Giovanny Vilcarino-Zevallos, Renzo Lopez, Andrea Matos, Cesar Ramal-Asayag, George Obregon, Laila Sara Arroyo Mühr   +16 more
doaj   +1 more source

Advances in Cancer Immunotherapy for Solid Tumors

Advanced Science, EarlyView.
Cancer immunotherapy for solid tumors is rapidly evolving beyond classical checkpoint blockade toward more precise strategies. Emerging checkpoint targets, bispecific antibodies, antibody–drug conjugate combinations, personalized vaccines, cellular therapies, and engineered cytokines are expanding therapeutic possibilities, while biomarker‐guided ...
Shira Gabizon‐Peretz, Harriet M. Kluger   +1 more
wiley   +1 more source

Examining pathways by which socioeconomic instability in adolescence influence sexual health during emerging adulthood in an agricultural setting in California

American Journal of Community Psychology, EarlyView.
Abstract This study investigates the longitudinal impact of socioeconomic instability on teen pregnancy and sexually transmitted infection (STI) diagnosis among adolescents and young adults (AYA) living in an agricultural region and examines pathways including supportive family and social structures, decision making autonomy in romantic relationships ...
Marie C. D. Stoner, Erica N. Browne, Marissa Raymond‐Flesch, Mary Kate Shapley‐ Quinn, Nivedita L. Bhushan, Alondra Jaime‐Aguilar, Carmen Ramirez, Jessica Huante, Daisy Gallardo, Sue Napierala, Megan Comfort, Alexandra M. Minnis   +11 more
wiley   +1 more source

Establishment and genetic characterization of cell lines derived from proliferating nasal polyps and sinonasal inverted papillomas

Scientific Reports, 2021
To better understand the pathogenesis of nasal polyps (NPs) and sinonasal inverted papillomas (SIPs), we aimed to establish cell lines from fresh tissues of NPs and SIPs and characterize them.
Thawaree Nukpook, Tipaya Ekalaksananan, Tohru Kiyono, Pornthep Kasemsiri, Watchareporn Teeramatwanich, Patravoot Vatanasapt, Surachat Chaiwiriyakul, Piti Ungarreevittaya, Jureeporn Kampan, Kanha Muisuk, Chamsai Pientong   +10 more
doaj   +1 more source