Results 81 to 90 of about 168,320 (317)

Clinical Validation of Four Point‐of‐Care High‐Risk HPV Assays, Including Two Reduced‐Valency Assays, for Cervical Cancer Screening in Low‐Resource Settings

International Journal of Cancer, EarlyView.
High‐risk human papillomavirus (hrHPV) testing improves cervical cancer screening by facilitating earlier detection and prevention. In low‐resource settings, however, cost and increased referrals limit its use. At the same time, many new and more affordable assays lack validation.
Neerja Bhatla, MaryLuz Rol, Seema Singhal, Showket Hussain, Anushree Patil, Pranay Tanwar, Shalini Singh, Vikrant M. Bhor, Kiran Munne, Richa Vashishtha, Shachi Vashist, Eric Lucas, Richard Muwonge, Arianis Tatiana Ramírez, Anju Singh, Vikas Khan, Jyoti Rani, Nasera Firdausi, Sandeep Sisodiya, Rutuja Wakchaure, María Alejandra Picconi, Alejandro Calderón, Margo Bell, Annemie De Smet, Alex Vorsters, Gary M. Clifford, Madhavi Chandra, Jitendra Kumar, Partha Basu   +28 more
wiley   +1 more source

Measuring HPV vaccination coverage in Australia: comparing two alternative population‐based denominators

Australian and New Zealand Journal of Public Health, 2015
Objective: To compare the use of two alternative population‐based denominators in calculating HPV vaccine coverage in Australia by age groups, jurisdiction and remoteness areas. Method: Data from the National HPV Vaccination Program Register (NHVPR) were
Bianca Barbaro, Julia M.L. Brotherton
doaj   +1 more source

Resource‐Adapted Triage Strategies for Women Testing HPV Positive With Self‐Collected Vaginal Samples in Cameroon

International Journal of Cancer, EarlyView.
Although human papillomavirus (HPV) testing is recommended for cervical cancer screening in low‐ and middle‐income countries, optimal management of HPV‐positive women remains undetermined, particularly in resource‐limited settings. Here, using data from the 3T study involving women in Cameroon, the authors evaluated the ability of extended HPV ...
Micol Murtas, Pierre Vassilakos, Ania Wisniak, Ketty Hu, Marc Arbyn, Gilles W. Tankeu Happi, Esther Abatsong, François Marcel Ndam Nsangou, Jean‐Christophe Tille, Essia Saiji, Bruno Kenfack, Patrick Petignat   +11 more
wiley   +1 more source

Tumor‐Regional Immune Microenvironment: A Critical Factor in the Design of Radiotherapy–Immunotherapy Combination Trials

International Journal of Cancer, EarlyView.
ABSTRACT Clinical trials combining radiotherapy (RT) with immune checkpoint blockade (ICB) have shown improved outcomes in only a fraction of patients, and optimal strategies for integrating these modalities remain under intense investigation. With a few exceptions, phase III combination trials have yielded disappointing results.
Xuanwei Zhang, Hui Wang, Weiyan Tang, Kai Kang, Kateryna Onyshchenko, Taotao Huang, Dan Liu, Jianxin Xue, You Lu, Gabriele Niedermann, Ren Luo   +10 more
wiley   +1 more source

Negative margins and negative HPV tests after large loop excision of the transformation zone: A nationwide historical cohort study

Acta Obstetricia et Gynecologica Scandinavica
Introduction Adequate treatment of cervical precancer, defined as negative margins and a negative HPV test post‐treatment, is essential for cervical cancer prevention, as inadequate excision of cervical precancer and a positive HPV test are associated ...
Ane‐Kersti Skaarup Knudsen, Tina Hovgaard Randrup, Ulrik Schiøler Kesmodel, Berit Bargum Booth, Line Winther Gustafson, Therese Koops Grønborg, Anne Hammer   +6 more
doaj   +1 more source

Financing of NCD Prevention in LMICs: Pakistan Case Study

Journal of the Pakistan Medical Association
Objective: The objective of this study is to estimate spending on NCD prevention in Pakistan and identify the enablers, challenges and dynamics underpinning population level NCD prevention spending, with particular focus on tobacco use, harmful use of ...
Ammar Rashid, Rozina Khalid, Kassim Nishtar, Saba Amjad, Huma Tahir   +4 more
doaj   +1 more source

HPV Testing Versus Cytology for Cervical Cancer Screening Among Women 50 Years and Older: Evidence From the HPV FOCAL Randomized Controlled Trial

International Journal of Cancer, EarlyView.
ABSTRACT Evidence on the comparative effectiveness of HPV testing versus cytology specifically in women aged ≥ 50 years who are approaching screening cessation remains limited. This analysis included 6471 women aged ≥ 50 at baseline screening in the HPV FOCAL randomized clinical trial. Women were randomly allocated to receive cytology (Control Group, n 
Md Saiful Alam, Laurie W. Smith, Lovedeep Gondara, Darrel Cook, Ruth Elwood Martin, Stuart Peacock, Lily Proctor, Gavin Stuart, David Patrick, Eduardo L. Franco, Mel Krajden, Anna Gottschlich, Gina S. Ogilvie   +12 more
wiley   +1 more source

HPV Serology and Circulating Viral DNA for Detection, Genotyping, and Measurement of Disease Burden in Oropharyngeal Cancer

International Journal of Cancer, EarlyView.
ABSTRACT The incidence of human papillomavirus‐positive (HPV+) oropharyngeal cancer (OPC) has increased rapidly, and HPV early antigen serology has been proposed as a scalable and cost‐effective early detection test. HPV seropositivity can precede clinical presentation of OPC by several years, so additional surveillance procedures may be necessary to ...
Lucas Penny, Eric Yang Stutheit‐Zhao, Birgitta E. Michels, Fabian Rosing, Zhen Zhao, Yangqiao Zheng, Jinfeng Zou, Shao Hui Huang, Johnny Carlton, Andrew McPartlin, John R. de Almeida, David Goldstein, Andrew Hope, Ali Hosni, John Kim, Fei‐Fei Liu, C. Jillian Tsai, John N. Waldron, Anna Spreafico, Enrique Sanz‐Garcia, Lillian L. Siu, Tim Waterboer, Geoffrey Liu, Scott V. Bratman   +23 more
wiley   +1 more source

Triage Performance of FAM19A4/miR124‐2 Methylation: 18‐Month Follow‐Up Results From a Prospective Observational Study Within the Dutch Primary HPV‐Based Cervical Screening Program

International Journal of Cancer, EarlyView.
ABSTRACT DNA methylation analysis of the genes FAM19A4 and miR124‐2 has emerged as a promising triage strategy for high‐risk (hr) human papillomavirus (HPV)‐positive women in cervical screening. This study reports a prospective evaluation of the diagnostic accuracy of FAM19A4/miR124‐2 methylation in a large population‐based primary HPV‐based screening ...
Lisanne Verhoef, Mila S. Griffioen, Maaike C. G. Bleeker, John W. J. Hinrichs, Albert G. Siebers, Albertus T. Hesselink, Chris J. L. M. Meijer, Renske D. M. Steenbergen, Johannes Berkhof, Daniëlle A. M. Heideman   +9 more
wiley   +1 more source

Human papillomavirus vaccination among childhood cancer survivors: A scoping review

Human Vaccines & Immunotherapeutics
Childhood cancer survivors are at increased risk for human papillomavirus (HPV) cancers yet are less likely to be vaccinated against HPV than the general population. This scoping review identified studies describing barriers, facilitators, and strategies
Pragya Gautam Poudel, Julia Brown, Tara M. Brinkman, Casey L. Daniel, Melissa M. Hudson, James L. Klosky, Kirsten K. Ness, Heather M. Brandt   +7 more
doaj   +1 more source