Results 51 to 60 of about 192,544 (305)

Validation in Zambia of a cervical screening strategy including HPV genotyping and artificial intelligence (AI)-based automated visual evaluation

Infectious Agents and Cancer, 2023
Background WHO has recommended HPV testing for cervical screening where it is practical and affordable. If used, it is important to both clarify and implement the clinical management of positive results.
Groesbeck P. Parham, Didem Egemen, Brian Befano, Mulindi H. Mwanahamuntu, Ana Cecilia Rodriguez, Sameer Antani, Samson Chisele, Mukatimui Kalima Munalula, Friday Kaunga, Francis Musonda, Evans Malyangu, Aaron Lunda Shibemba, Silvia de Sanjose, Mark Schiffman, Vikrant V. Sahasrabuddhe   +14 more
doaj   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Epidemiological evidence and association of human papillomavirus with esophageal cancer in northeastern Thailand: a case–control study

Frontiers in Microbiology, 2023
Recently, epidemiological evidence of high-risk human papillomavirus (hrHPV) and its association with the increasing risk of esophageal cancer (EC) have been described.
Ati Burassakarn, Ati Burassakarn, Chamsai Pientong, Chamsai Pientong, Panwad Tongchai, Weerayut Wongjampa, Weerayut Wongjampa, Arisara Poosari, Apiradee Udomsin, Prakasit Sa-ngiamwibool, Piti Ungareewittaya, Thitima Nutravong, Tipaya Ekalaksananan, Tipaya Ekalaksananan   +13 more
doaj   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

An in vitro model and the underlying pathways of sinonasal inverted papilloma development

Scientific Reports, 2023
Recently, the specific association between Sinonasal inverted papilloma (SIP) and EGFR exon 20 mutations has been reported. To investigate the link between specific EGFR mutations and SIP development, we established organotypic raft culture system using ...
Thawaree Nukpook, Tohru Kiyono, Tipaya Ekalaksananan, Pornthep Kasemsiri, Watchareporn Teeramatwanich, Patravoot Vatanasapt, Surachat Chaiwiriyakul, Tomomi Nakahara, Chamsai Pientong   +8 more
doaj   +1 more source

Self‐Assembly of Antigenic Peptide Nanofibrils Templates the Growth of Silica Nanoparticles for Nanovaccines

Advanced Science, EarlyView.
Antigenic peptides Aβ42 and E7 self‐assemble into nanofibrils; APTES and TEOS induce SiO2 NP formation on these fibrils to form SiO2@fibril nanovaccines, which activate BMDCs in vitro. In vivo, SiO2@Aβ42 fibril nanovaccines alleviate AD symptoms and clear Aβ42 plaques in APP/PS1 mice, and SiO2@E7 fibril nanovaccines inhibit tumor growth and promote ...
Xuecheng Yang, Min Li, Zhiying Yao, Yu Hu, Zhili Wang, Wendi Shi, Bingbing Sun   +6 more
wiley   +1 more source

Phase Separation of TRIM21 Modulates PTPN14 Stability to Drive Flow‐Dependent Endothelial Activation and Atherogenesis

Advanced Science, EarlyView.
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He, Qiannan Ma, Xue Wang, Jiaxu Mang, Chufeng Li, Bingjun Wu, Liu Yao, Yequn Chen, Qiankun Bao, Yi Zhu, Jinlong He   +10 more
wiley   +1 more source

Anal PAP, HPV tests and magnifying chromoendoscopy with biopsies in the diagnosis of anal intraephitelial neoplasia

Journal of Coloproctology, 2020
Introduction: Anal intraepithelial neoplasia (AIN) is the most likely precursor of squamous cells cancer which represents 90% of anal cancers. The use of biomolecular tests as a screening method has been extended by gynecology.
Carmen Aguiar, Laura García, María Belén Boccardo, Macarena Vassel, Alejandra Arriola, Sylvia Jaumandreu, María Carmen Rodríguez, Carmen Alvarez, Isabelle Heard   +8 more
doaj   +1 more source

Detection and genotyping of human Papillomavirus in urine samples from unvaccinated male and female adolescents in Italy [PDF]

, 2013
The introduction of vaccination against Human Papillomavirus (HPV) in adolescent girls in 2006 has focused virological surveillance on this age group. As few studies have evaluated HPV infections in young populations, further data are needed in order to ...
Zotti, CM, Boccalini, Sara, Elisabetta Tanzi, Gasparini Roberto, Coppola Rosa Cristina, R. Gasparini, Rosa Cristina Coppola, Coppola, RC, Gasparini R, Paolo Castiglia, M. Martinelli, M. Martinese, Panatto D, Silvia Bianchi, Amicizia, D, Amicizia D, Paolo Bonanni, Zotti CM, Elena Rosanna Frati, Bianchi S, Bianchi, S, Martinelli, M, Castiglia Paolo, Bianchi Silvia, D. Panatto, Marianna Martinelli, Meloni, Angelo, Tanzi Elisabetta, Amicizia, Daniela, G. Masia, Masia Giuseppina, Zotti, Carla Maria, Bianchi, Silvia, Daniela Amicizia, Bonanni, Paolo, Martinese M, Martinese, M, Masia G, Castiglia, Paolo Giuseppino, Tanzi, Elisabetta, S. Bianchi, Morena Martinese, C. M. Zotti, P. Castiglia, Coppola R C, Boccalini, S, Amicizia Daniela, Boccalini S, Martinelli Marianna, Bonanni Paolo, Bonanni P, Panatto, Donatella, Panatto Donatella, Frati, ER, Tanzi E, Zotti Carla Maria, Martinelli, Marianna, Frati ER, Piana Andrea, Tanzi, E., Piana A, Martinese, Morena, Gasparini, Roberto, Gasparini, R, Castiglia P, Donatella Panatto, Meloni Angelo, Martinese Morena, Sara Boccalini, D. Amicizia, E. Tanzi, Andrea Piana, P. Bonanni, Panatto, D, Meloni, A, Frati, Elena Rosanna, Masia, Giuseppina, Piana, Andrea Fausto, Boccalini Sara, Giuseppina Masia, R. C. Coppola, A. Meloni, E.R. Frati, Angelo Meloni, S. Boccalini, Roberto Gasparini, Frati Elena Rosanna, Masia, G, A. Piana, Martinelli M, Coppola, Rosa Cristina, Meloni A, Carla Maria Zotti, Bonanni, P   +93 more
core   +2 more sources

Posthumously Diagnosed Myhre Syndrome Presenting With Pleural Remodeling and Endometrial Cancer

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome (OMIM 139210) is a genetic condition defined by neurodevelopmental disability, characteristic facial features, and multisystem proliferative fibrosis. While various types of lung disease have been reported, pleural remodeling leading to restrictive lung disease has not yet been described.
Jeanette Saffir, Karee Morgan, Karigynn Chaimson, Blake E. Funke, Kim L. Sandler, Melissa Hogan, Thomas Cassini   +6 more
wiley   +1 more source