Results 21 to 30 of about 168,320 (317)

Prevalence and risk factors for oral human papillomavirus and Epstein-Barr virus co-infections among sexually active males and females in Ibadan, Nigeria

BMC Oral Health
Background Co-infection of Human papillomavirus (HPV) and Epstein–Barr virus (EBV) is associated with oral and oropharyngeal cancers. This study examined the prevalence and associated risk factors for oral HPV and EBV co-infection among sexually active ...
Adeola Fowotade, Deborah Oke, Yusuf Bello, Adekunle Daniel, Akinyele Adisa, Moses Adewumi, Margaret Okoeguale, Olasunkanmi Olisa, Yinan Zheng, Deborah Watson-Jones, Isaac Adewole, Robert Murphy, Lifang Hou, Imran O. Morhason-Bello   +13 more
doaj   +1 more source

Validation in Zambia of a cervical screening strategy including HPV genotyping and artificial intelligence (AI)-based automated visual evaluation

Infectious Agents and Cancer, 2023
Background WHO has recommended HPV testing for cervical screening where it is practical and affordable. If used, it is important to both clarify and implement the clinical management of positive results.
Groesbeck P. Parham, Didem Egemen, Brian Befano, Mulindi H. Mwanahamuntu, Ana Cecilia Rodriguez, Sameer Antani, Samson Chisele, Mukatimui Kalima Munalula, Friday Kaunga, Francis Musonda, Evans Malyangu, Aaron Lunda Shibemba, Silvia de Sanjose, Mark Schiffman, Vikrant V. Sahasrabuddhe   +14 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Access to HPV vaccination for boys in the United Kingdom

Medicine Access @ Point of Care, 2018
Human papillomavirus (HPV) is a common sexually transmitted infection. There is a well-established link between HPV and the development of cervical cancer, but HPV infection is also associated with vaginal and vulvar cancer, head and neck cancers as well
Gillian Prue, David Grimes, Peter Baker, Mark Lawler   +3 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Patterns of blood pressure and factors associated with hypertension among young adults in Ibadan, Nigeria

BMC Cardiovascular Disorders
Background Hypertension is increasingly recognised among younger adults and contributes to early cardiovascular risk, yet population-level data in this age group remain limited in many low- and middle-income countries. This study examined the patterns of
Deborah Oke, Okechukwu Ogah, Yusuf Bello, Oluwatosin Lawal, Yusuf Kareem, Ololade Adeyemi, Oluwatoyin Olalemi, Babatunde Adedokun, Babatunde Salako, Isaac Adewole, Deborah Watson-Jones, Imran Morhason-Bello   +11 more
doaj   +1 more source

An in vitro model and the underlying pathways of sinonasal inverted papilloma development

Scientific Reports, 2023
Recently, the specific association between Sinonasal inverted papilloma (SIP) and EGFR exon 20 mutations has been reported. To investigate the link between specific EGFR mutations and SIP development, we established organotypic raft culture system using ...
Thawaree Nukpook, Tohru Kiyono, Tipaya Ekalaksananan, Pornthep Kasemsiri, Watchareporn Teeramatwanich, Patravoot Vatanasapt, Surachat Chaiwiriyakul, Tomomi Nakahara, Chamsai Pientong   +8 more
doaj   +1 more source

Epidemiological evidence and association of human papillomavirus with esophageal cancer in northeastern Thailand: a case–control study

Frontiers in Microbiology, 2023
Recently, epidemiological evidence of high-risk human papillomavirus (hrHPV) and its association with the increasing risk of esophageal cancer (EC) have been described.
Ati Burassakarn, Ati Burassakarn, Chamsai Pientong, Chamsai Pientong, Panwad Tongchai, Weerayut Wongjampa, Weerayut Wongjampa, Arisara Poosari, Apiradee Udomsin, Prakasit Sa-ngiamwibool, Piti Ungareewittaya, Thitima Nutravong, Tipaya Ekalaksananan, Tipaya Ekalaksananan   +13 more
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source