Results 61 to 70 of about 67,909 (325)

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Atypical Proliferating Trichilemmal Cyst with Malignant Breast Skin Transformation: A Case Report and Review of the Literature

open access: yesCase Reports in Oncological Medicine, 2016
Proliferating trichilemmal tumors (PTTs) are benign adnexal skin neoplasms that arise from the outer root sheath of the hair follicle. These tumors are most commonly observed on the scalp and occur, most of the time, in elderly women.
Marino Antonio Capurso-García   +6 more
doaj   +1 more source

Cáncer de mama triple negativo con metástasis interescapular

open access: yesRevista Científica Ciencias de la Salud, 2023
El cáncer de mama triple negativo es una presentación clínica poco frecuente, pero de manejo difícil del cáncer de mama, en el que la metástasis a partes blandas como primera manifestación clínica es rara.
Sergio Adrian Barreto Roman   +2 more
doaj   +1 more source

Tamizaje del cáncer de mama: certezas y controversias [PDF]

open access: yes, 2017
El cáncer de mama es globalmente el de mayor incidencia en mujeres, con estimaciones de entre 1.7 y 2.4 millones de casos anuales según diferentes fuentes1, 2.
Luthy, Isabel Alicia
core  

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Afrontamiento y calidad de vida en pacientes con cáncer de mama. [PDF]

open access: yes, 2009
150 p.El diagnóstico de cáncer de mama es la tercera causa de muerte por cáncer en la mujer Chilena, y constituye una de las situaciones de mayor carga y estrés emocional para quienes lo padecen.
Escobar Ponce, Francisca Paz   +1 more
core  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Nosotros [PDF]

open access: yes, 2017
Reflexión personal sobre la experiencia en primera persona de un proceso de cáncer de ...
Alonso Breto, Isabel
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

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