Results 41 to 50 of about 370,490 (179)

A pan‐tumor review of the role of poly(adenosine diphosphate ribose) polymerase inhibitors

CA: A Cancer Journal for Clinicians, Volume 75, Issue 2, Page 141-167, March/April 2025.
Abstract Poly(adenosine diphosphate ribose) polymerase (PARP) inhibitors, such as olaparib, talazoparib, rucaparib, and niraparib, comprise a therapeutic class that targets PARP proteins involved in DNA repair. Cancer cells with homologous recombination repair defects, particularly BRCA alterations, display enhanced sensitivity to these agents because ...
Chadi Hage Chehade, Georges Gebrael, Nicolas Sayegh, Zeynep Irem Ozay, Arshit Narang, Tony Crispino, Talia Golan, Jennifer K. Litton, Umang Swami, Kathleen N. Moore, Neeraj Agarwal   +10 more
wiley   +1 more source

Hydrocortisone therapy in a cat with vasopressor‐refractory septic shock and suspected critical illness‐related corticosteroid insufficiency

Clinical Case Reports, Volume 5, Issue 7, Page 1123-1129, July 2017., 2017
A 27‐month‐old female cat was presented with septic peritonitis secondary to a ruptured pyometra and subsequent pyothorax. Vasopressor‐refractory septic shock led to a suspicion of critical illness‐related corticosteroid insufficiency, successfully treated with intravenous hydrocortisone. Previous megestrol acetate administration may have played a role
Simone R. R. Pisano, Judith Howard, Horst Posthaus, Alan Kovacevic, Ivayla D. Yozova   +4 more
wiley   +1 more source

Tendências de Incidência e Mortalidade por Câncer de Ovário nos Países da América Latina

Revista Brasileira de Cancerologia, 2020
Introdução: O câncer de ovário é o sétimo mais comum e a nona causa de morte por câncer em mulheres, no mundo. Na América Latina, o câncer é a segunda causa de morte, e as projeções indicam um provável crescimento no número de mortes entre os anos 2012 e
Maria Aparecida Paulo dos Santos, Fábia Cheyenne Gomes de Morais Fernandes, Emelynne Gabrielly de Oliveira Santos, Dyedo Leandro Bezerra de Souza, Isabelle Ribeiro Barbosa   +4 more
doaj   +1 more source

Avanços na Detecção Precoce e Tratamento de Câncer de Ovário: Uma análise dos métodos mais recentes de diagnóstico e abordagens terapêuticas

Brazilian Journal of Implantology and Health Sciences, 2023
O câncer de ovário é um dos desafios mais significativos na oncologia devido ao seu diagnóstico frequentemente tardio e taxas elevadas de mortalidade.
Luiz Henrique Dominguez Júnior, R. G. Ferreira, Leonardo Ambrósio Domingues, Fernando Buzeti Garcia, Maria Lúcia Marin Cominotti   +4 more
semanticscholar   +1 more source

Clinical utility of ultrasonography in pediatric and adolescent gynecology: retrospective review of 1313 ultrasound examinations

Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 2, Page 226-234, February 2025.
ABSTRACT Objectives Ultrasound is the first‐line imaging modality of the pelvis in the pediatric and adolescent gynecology (PAG) population. Ultrasound findings in pre‐ and postpubertal PAG patients differ from those in adults. Diagnostic models for adnexal pathology have not been validated in this cohort.
N. Cooper, H. Meehan, K. Linton‐Reid, J. Barcroft, J. Danin, M. Seah, S. Sadigh, N. Bharwani, S. Sur, C. Fotopoulou, C. Landolfo, J. Yazbek, S. Saso, D. Timmerman, T. Bourne, M. Al‐Memar   +15 more
wiley   +1 more source

An Immunohistochemical Study on the Expression of Sex Steroid Receptors in Canine Mammary Tumors

International Scholarly Research Notices, Volume 2012, Issue 1, 2012., 2012
Steroid hormones are found to play a major role in the genesis and progression of mammary tumors. The aim of this study was to immunohistochemically detect the presence of estrogen receptor alpha (ERα), estrogen receptor beta (ERβ), and progesterone receptor (PR) and also to study the association between these markers in 29 cases of benign (11) and ...
Leena Rajathy Port Louis, Khub Chandra Varshney, Madhavan Gopalakrishnan Nair, T. Agui, W. C. Wilson   +4 more
wiley   +1 more source

Hyperandrogenism produced by ovarian tumors in women at different life stages.

Revista de la Facultad de Ciencias Médicas de Córdoba, 2014
Objective: to evaluate the different presentations of hyperandrogenism produced by ovarian tumors in women at different life stages Design: case report Setting: academic institutions Patient(s): 3 patients at different life stages, with increased ...
Carolina Fuox-Otta, Paula Szafryk de Mereshian, Mónica López de Corominas, Margarita Fuster, Carlos R López   +4 more
doaj   +1 more source

Prevalência e fatores sociodemográficos associados ao óbito por câncer de ovário em um município do interior de Minas Gerais, Brasil, 2013-2024

Revista Eletrônica Acervo Saúde
Objetivo: Investigar a prevalência do óbito e fatores sociodemográficos de pacientes diagnosticadas com câncer de ovário no município de Barbacena, Minas Gerais.
Fábio Felipe de Sá, Franciane Lemos Fernandes de Carvalho, Marinna Gorgulho Sciavicco, Nathanny da Silva de Lemos, Paolo Giuseppe Sciavicco, Tatiane Kely Alves Puiatti, Juliano Bergamaschine Mata Diz, Flaviany Custódio Faria   +7 more
semanticscholar   +1 more source

Sobrevida global y sobrevida libre de enfermedad a cinco y diez años en pacientes con cáncer de ovario

Oncología (Ecuador), 2023
Introducción: La supervivencia del cáncer de ovario se aproxima al 50%, sin embargo, varía en función de los distintos factores pronósticos, siendo el principal la extensión de la enfermedad al diagnóstico. El objetivo del presente estudio fue establecer
Micaela Alejandra Navarrete Rengel, Jimmy Ronald Casares Tamayo, Rommel Espinoza de los Monteros   +2 more
semanticscholar   +1 more source

Evaluación del proceso de atención a la mujer con sospecha de cáncer de ovario en la Atención Primaria de Cataluña

Revista Clínica de Medicina de Familia
Introducción La supervivencia a los 5 años de las mujeres europeas con cáncer de ovario es inferior al 50%, y existen importantes variaciones según el sistema de salud y el rol de la Atención Primaria.
Carmen Vela Vallespín
semanticscholar   +1 more source