Results 41 to 50 of about 61,140,294 (163)

Fuzuloparib with or without apatinib as maintenance therapy in newly diagnosed, advanced ovarian cancer (FZOCUS‐1): A multicenter, randomized, double‐blind, placebo‐controlled phase 3 trial

CA: A Cancer Journal for Clinicians, Volume 76, Issue 1, January/February 2026.
Abstract Although poly(adenosine diphosphate‐ribose) polymerase inhibitors (PARPis) and bevacizumab were approved as first‐line maintenance for advanced ovarian cancer (OC), evidence comparing this combination with PARPi monotherapy, especially in BRCA‐mutated/homologous recombination‐deficient (HRD) patients, is lacking.
Lingying Wu, Jing Wang, Qingshui Li, Danbo Wang, Cuiying Zhang, Junying Tang, Guonan Zhang, Min Hao, Desheng Yao, Qinglei Gao, Youzhong Zhang, Ruifang An, Rutie Yin, Li Wang, Bairong Xia, Qi Zhou, Hongying Yang, Jianqing Zhu, Kui Jiang, Zhengzheng Chen, Qiang Wu, Wei Duan, Yi Huang, Hui Zhang, Shuqing Wei, Guiling Li, Yuanguang Meng, Ke Wang, Xinfeng Yang, Xianghua Huang, Lingya Pan, Jinjin Yu, Ge Lou, Yu Zhang, Huaijun Zhou, Xiaoqing Guo, Hong Yang, Xiaodong Cheng, Xiumin Li, Wuliang Wang, Hongqin Zhao, Yunxia Li, Yingjie Yang, An Lin, Wenjun Cheng, Lihong Chen, Xiaoying Xie, Wen Di, Yuanjing Hu, Mo Chen, Hongwu Wen, Liping Cai, Xiaohua Wu, Zhongqiu Lin, Quanren Wang, Xinfeng Yang, Ning Li   +56 more
wiley   +1 more source

Abstracts

, 2021
Research and Practice in Thrombosis and Haemostasis, Volume 5, Issue S2, October 2021.
wiley   +1 more source

A pan‐tumor review of the role of poly(adenosine diphosphate ribose) polymerase inhibitors

CA: A Cancer Journal for Clinicians, Volume 75, Issue 2, Page 141-167, March/April 2025.
Abstract Poly(adenosine diphosphate ribose) polymerase (PARP) inhibitors, such as olaparib, talazoparib, rucaparib, and niraparib, comprise a therapeutic class that targets PARP proteins involved in DNA repair. Cancer cells with homologous recombination repair defects, particularly BRCA alterations, display enhanced sensitivity to these agents because ...
Chadi Hage Chehade, Georges Gebrael, Nicolas Sayegh, Zeynep Irem Ozay, Arshit Narang, Tony Crispino, Talia Golan, Jennifer K. Litton, Umang Swami, Kathleen N. Moore, Neeraj Agarwal   +10 more
wiley   +1 more source

Hydrocortisone therapy in a cat with vasopressor‐refractory septic shock and suspected critical illness‐related corticosteroid insufficiency

Clinical Case Reports, Volume 5, Issue 7, Page 1123-1129, July 2017., 2017
A 27‐month‐old female cat was presented with septic peritonitis secondary to a ruptured pyometra and subsequent pyothorax. Vasopressor‐refractory septic shock led to a suspicion of critical illness‐related corticosteroid insufficiency, successfully treated with intravenous hydrocortisone. Previous megestrol acetate administration may have played a role
Simone R. R. Pisano, Judith Howard, Horst Posthaus, Alan Kovacevic, Ivayla D. Yozova   +4 more
wiley   +1 more source

Anticonceptivos hormonales combinados y cáncer de ovario [PDF]

, 2016
La anticoncepción hormonal combinada es un método anticonceptivo altamente eficaz que actualmente sigue usándose poco a pesar de su seguridad y los beneficios que puede aportar a la salud de las mujeres más allá de evitar embarazos.
García Andreu, María del Mar, González Navarro, José Vicente   +1 more
core  

Clinical utility of ultrasonography in pediatric and adolescent gynecology: retrospective review of 1313 ultrasound examinations

Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 2, Page 226-234, February 2025.
ABSTRACT Objectives Ultrasound is the first‐line imaging modality of the pelvis in the pediatric and adolescent gynecology (PAG) population. Ultrasound findings in pre‐ and postpubertal PAG patients differ from those in adults. Diagnostic models for adnexal pathology have not been validated in this cohort.
N. Cooper, H. Meehan, K. Linton‐Reid, J. Barcroft, J. Danin, M. Seah, S. Sadigh, N. Bharwani, S. Sur, C. Fotopoulou, C. Landolfo, J. Yazbek, S. Saso, D. Timmerman, T. Bourne, M. Al‐Memar   +15 more
wiley   +1 more source

An Immunohistochemical Study on the Expression of Sex Steroid Receptors in Canine Mammary Tumors

International Scholarly Research Notices, Volume 2012, Issue 1, 2012., 2012
Steroid hormones are found to play a major role in the genesis and progression of mammary tumors. The aim of this study was to immunohistochemically detect the presence of estrogen receptor alpha (ERα), estrogen receptor beta (ERβ), and progesterone receptor (PR) and also to study the association between these markers in 29 cases of benign (11) and ...
Leena Rajathy Port Louis, Khub Chandra Varshney, Madhavan Gopalakrishnan Nair, T. Agui, W. C. Wilson   +4 more
wiley   +1 more source

Una investigación española desvela el doble papel de una proteína en el cáncer de ovario [PDF]

, 2014
Nota de prensa sobre la utilidad de NIS, una proteína transportadora de yodo, como marcador tumoral y potencial terapéutico en cáncer de ovario. NIS, una proteína transportadora de yodo presente en distintos órganos, puede ser una herramienta en el ...
Instituto de Salud Carlos III. Gabinete de prensa
core   +1 more source

Nuevas aproximaciones para el tratamiento del cáncer de ovario [PDF]

, 2022
[ES] El cáncer de ovario es el tipo de cáncer ginecológico con peores ratios de supervivencia debido, principalmente, a un diagnóstico en estadios avanzados de la enfermedad y a la aparición de resistencias y recaídas al tratamiento quimioterápico ...
Ovejero-Sánchez, María
core   +1 more source

Role of immune checkpoint inhibitors combined with chemotherapy in recurrent drug‐resistant gestational trophoblastic neoplasia: Four case reports and literature review

Cancer Reports, Volume 7, Issue 3, March 2024.
Abstract Background Multiple studies have confirmed that programmed cell death 1 (PD‐1) and programmed cell death ligand 1 (PD‐L1) is widely expressed in gestational trophoblastic neoplasia (GTN) tissues. Therefore, immune checkpoint inhibitors may be an option for the treatment of recurrent and drug‐resistant GTN.
Weiqing Liu, Yukai Zhu, Ya Wang, Rong Li, Dongling Zou, Rui Chen, Lu Yang, Yu Huang   +7 more
wiley   +1 more source