Results 21 to 30 of about 1,528 (138)

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise   +2 more
wiley   +1 more source

Exercise training prior to and during cancer in mice preserves muscle mass, reduces tumour weight and suppresses molecular mediators of cachexia

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend PoWeR training (11.5 weeks of voluntary wheel running with progressively increased resistance) before and during cancer attenuates muscle loss, limits tumour growth, drives a transition toward a more oxidative muscle phenotype (IIB‐to‐IIA shift), downregulates cachexia‐associated pathways and enhances mitochondrial performance in
Stavroula Tsitkanou   +13 more
wiley   +1 more source

Trasplante cardíaco y su relación con el cáncer de piel de tipo melanoma y no melanoma

open access: yesRevista de la Asociación Colombiana de Dermatología y Cirugía Dermatológica, 2014
El trasplante cardíaco es una cirugía que cada vez se hace con mayor frecuencia en nuestro medio. En la Clínica Cardio VID de Medellín aumenta cada año el número de pacientes a quienes se les practica este procedimiento.
Claudia Marcela Gaviria   +2 more
doaj   +1 more source

The 9th International RASopathies Symposium

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1934-1941, August 2026.
ABSTRACT The RASopathies are a group of congenital disorders with overlapping clinical manifestations that are caused by pathogenic germline or early somatic variants that result in the hyperactivation of the RAS/mitogen‐activated protein kinase (MAPK) signaling pathway.
Pau Castel   +41 more
wiley   +1 more source

Atypical fibroxanthoma in an elderly

open access: yesMedisan, 2020
The  case report of a 72 years old man  who presented a dorsal cutaneous neoplasm is described, reason why he was assisted in a multidisciplinary way in 2 hospitals from  Santiago de Cuba.  Given the preoperative diagnosis of skin basal cell epithelioma  
Rafael Manuel Neyra Barros   +2 more
doaj  

Sickle Cell Disease and Kidney Injury: Circulating Uromodulin Allows Early Tissue Specific Diagnosis and Monitoring of Treatment

open access: yes
American Journal of Hematology, EarlyView.
Ferras Alashkar   +10 more
wiley   +1 more source

Advances in Human Mass Balance Studies: An IQ Consortium Perspective on Current Practices and Emerging Trends

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 43-54, July 2026.
Human radiolabeled mass balance studies are crucial for comprehensively characterizing the absorption, distribution, metabolism, and excretion (ADME) of investigational drugs, providing essential data for drug development, regulatory evaluation, and product labeling.
Jason Boer   +24 more
wiley   +1 more source

Cáncer de piel y ocupación

open access: yesRevista Cubana de Medicina, 2001
Se conoce que el cáncer cutáneo es el más frecuente en el hombre, con un incremento actual de su incidencia que afecta de manera considerable la población adulta laboralmente activa, con sus repercusiones económicas y sociales, y su consecuente deterioro
Roberto Rodríguez García   +2 more
doaj  

Conocimientos y frecuencia de uso del protector solar en estudiantes de medicina de una universidad peruana

open access: yesRevista de la Facultad de Medicina Humana
Objetivo: Determinar el nivel de conocimientos y la frecuencia de uso del protector solar en estudiantes de medicina de una universidad peruana. Materiales y métodos: Investigación analítica de corte transversal en 302 estudiantes, de ambos géneros y
Luciana Yep   +7 more
doaj   +1 more source

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

open access: yesThe FEBS Journal, Volume 293, Issue 13, Page 3881-3898, July 2026.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin   +2 more
wiley   +1 more source

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