Results 91 to 100 of about 146,764 (292)
Real‐Time In Vivo Monitoring of Anastomotic Intestinal Ischemia Using Implantable Resorbable Organic Sensors
Advanced Science, EarlyView.Resorbable impedance sensors are successfully implanted into porcine small intestinal anastomoses. Impedance was recorded for 2 hours prior, and 2 hours following ischemia induction, and a significant drop in tissue impedance was observed. Abstract
Anastomotic failure remains one of the most severe complications in gastrointestinal surgery.Dennis Wahl, Finn Jaekel, Julia Henne, Richard Kantelberg, Daniel C. Freund, Eberhard Grambow, Brigitte Vollmar, Amelie R. Zitzmann, Hans Kleemann, Jochen Hampe, Sebastian Hinz, Clemens Schafmayer, Karl Leo +12 morewiley +1 more sourceOnline adaptive MR-guided radiotherapy: Conformity of contour adaptation for prostate cancer, rectal cancer and lymph node oligometastases among radiation therapists and radiation oncologists. [PDF]
Tech Innov Patient Support Radiat Oncol, 2022 Rasing MJA, Sikkes GG, Vissers NGPM, Kotte ANTJ, Boudewijn JH, Doornaert PAH, Eppinga WSC, Intven M, Rutgers RHA, Scheeren A, Snoeren LMW, Vlig TB, van der Voort van Zyp JRN, Wijkhuizen LM, van Rossum PSN, Peters M, Jürgenliemk-Schulz IM. +16 moreeuropepmc +1 more sourceGlobal surveillance of cancer survival 1995-2009: analysis of individual data for 25,676,887 patients from 279 population-based registries in 67 countries (CONCORD-2) [PDF]
, 2015 BACKGROUND:
Worldwide data for cancer survival are scarce. We aimed to initiate worldwide surveillance of cancer survival by central analysis of population-based registry data, as a metric of the effectiveness of health systems, and to inform global ...A. Ab Manan, A. Belot, A. Bonaventure, A. Bordoni, A. Caldarella, A. Chiolero, A. Dyzmann Sroka, A. Eberle, A. Fabowale, A. Gavin, A. Giacomin, A. Hakenewerth, A. Ioka, A. Katalinic, A. Krasilnikov, A. Lalany, A. Madeddu, A. Mateos, A. Maurina, A. Mayer da Silva, A. Monnereau, A. Nandakumar, A. Nennecke, A. Pate, A. Schwartz, A. Shibata, A. Spitale, A. Stroup, A. Sutera, A. Venn, A. Verdecchia, A. Znaor, A. Zucchetto, A.A. Zborovskaya, A.C. Kataki, A.G. Hudson, A.I. Marcos, A.I. Todescu, A.J. Coldman, A.M. Al Khater, A.M. Bouvier, A.M. da Costa Miranda, A.M. Jofre, A.R. Kahn, A.S. Verdugo, A.S. Woronoff, A.U. Radziszewska, A.V. Guizard, A.W. Demetriou, B. Camey, B. Carballo Quintero, B. Holleczek, B. Huang, B. Lapôtre Ledoux, B. Malle, B. Møller, B. Rachet, B. Trétarre, B. Warther, B. Wohler, B. Zhang, B.C. Stokes, B.G. Silverman, B.K. Edwards, B.Y. Hernandez, C. Allemani, C. Bertrand, C. Bouchardy, C. Brook, C. Cirilli, C. Daniel, C. Hermann, C. Key, C. Laporte, C. Lewis, C. Navarro, C. Ochir, C. Phillips, C. Rao, C. Russell, C. Sacerdote, C. Safaei Diba, C. Scandiuzzi, C. Scott, C. Stiller, C. Sweeney, C. White, C. Wiggins, C.A. Lima, C.D. Stefan, C.E. Kuehni, C.F. Lynch, C.I. Yakut, C.J. Chiang, C.J. Johnson, C.J. Uribe, C.L. Veneziano, C.R. Torres Cintrón, D. Agius, D. Baker, D. Bradshaw, D. Coza, D. Currow, D. Deapen, D. Degré, D. Forman, D. Garcilazo, D. Greenberg, D. Lemons, D. Meechan, D. Pongnikorn, D. Serraino, D. Spika, D. Turner, D. West, D.A. Herrmann, D.B. Rogers, D.B. Veneziano, D.E. Nishri, D.H. Brewster, D.K. O'Brien, D.K. Shipley, D.L. Rousseau, D.L. Zhao, D.M. Hurley, D.M. Jurado, D.W. Huws, E. Almar, E. Ardanaz, E. Bah, E. Barrios, E. Chalker, E. Cornet, E. Crocetti, E. Davies, E. Kumar, E. Laura, E. Liepina, E. Lobo, E. Molina, E. Morris, E. Sirri, E. Suzanna, E.J. Ólafsdóttir, F. Bannon, F. Berrino, F. Falcini, F. La Rosa, F. Martínez Reyes, F. Molinié, F. Moreno, F. Pannozzo, F. Sassi, F. Stracci, F. Tisano, F. Vigneau, F. Vitale, F.G. Levi, F.R. McCrate, F.V. Pugh, FD: Zhu, G. Azevedo e. Silva, G. Candela, G. Copeland, G. Engholm, G. Forjaz, G. Gatta, G. Gola, G. Launoy, G. Lawrence, G. Leung, G. Lopez Guarnizo, G. Mazzoleni, G. Noonan, G. Smailyte, G. Spivak, G. Tagliabue, G. Tortolero Luna, G.G. Giles, G.H. Song, G.M. Hosain, G.P. Guo, H. Al Eid, H. Brenner, H. Carreira, H. Comber, H. Farrugia, H. Hannah, H. Ito, H. Jerry, H. Kajueter, H. Mühlböck, H. Ryan, H. Sriplung, H. Storm, H. Stuart Panko, H. Sugiyama, H. Sundseth, H. You, H. Zeng, H.K. Weir, H.M. Ge, I. Konzelmann, I. Kumcher, I. Oki, J. Adamcik, J. Bastos, J. Bates, J. Bidaurrazaga, J. Butler, J. Błaszczyk, J. Clavel, J. Didkowska, J. Estève, J. Faivre, J. Galceran, J. George, J. Kieschke, J. Martin, J. Poole, J. Rashbass, J. Stare, J. Verne, J. Walrath, J. Wang, J. Wilkinson, J. Yépez, J.A. MacKinnon, J.A. Moya, J.C. de Oliveira, J.C. Galaz, J.G. Chen, J.G. Tang, J.H. Zhang, J.L. Young, J.M. Dong, J.M. Díaz García, J.M. Lutz, J.P. Fulton, J.R. Espinoza, J.R. Quirós, J.R. Rees, J.S. Chen, J.T. Brockhouse, J.V. Ahn, K. Daoprasert, K. Davidson Allen, K. Del Pino, K. Emrich, K. Henau, K. Herget, K. Katayama, K. Kosa, K. Kępska, K. Linklater, K. Nakata, K. Seppä, K. Stern, K. Suwanrungruang, K. Wei, K.A. Vriends, K.C. Ngan, K.C. Ward, K.I. Robb, K.M. McKeen, K.S. Pawlish, K.W. Jung, L. Almon, L. Antunes, L. Cremone, L. Giljahn, L. Jaidane, L. Jaramillo, L. Keinan Boker, L. Liu, L. Mangone, L. Marrett, L. Mueller, L. Newman, L. Shack, L. Stephenson, L. Tryggvadóttir, L. Van Eycken, L. Yang, L.E. Bravo, L.L. Williamson, L.P. Cheng, M. Abdel Rahman, M. Autelitano, M. Bielska Lasota, M. Budroni, M. Castaing, M. Colonna, M. Corti, M. Daoulas, M. Esterly, M. Federico, M. Fusco, M. Gądalska Lampart, M. Hackl, M. Hamdi Chérif, M. Hattori, M. Hood, M. Krishnatreya, M. Lambe, M. MacIntyre, M. Maspoli Conconi, M. Maynadié, M. Michiara, M. Mokni, M. Mounier, M. Murphy, M. Mägi, M. Patil, M. Peake, M. Piñeros, M. Primic Žakelj, M. Ramos Montserrat, M. Roche, M. Ruta, M. Sant, M. Trojanowski, M. Usala, M. Usel, M. Utada, M. Valkov, M. Velten, M. Vercelli, M. Zvolský, M. Šekerija, M.A. Green, M.A. Whiteside, M.A. Williams, M.B. Keitheri Cheteri, M.C. Diumenjo, M.C. Hsieh, M.C. Yepes, M.D. Chirlaque, M.D. Green, M.E. Torrent, M.F. Lanza, M.F. Vitale, M.G. Harrelson, M.J. Bento, M.J. Schymura, M.J. Soeberg, M.J. Sánchez, M.L. Vilardell Gil, M.M. El Mistiri, M.M. El Mistiri, M.P. Coleman, M.P. Curado, M.S. González, M.S. Lai, M.V. Argüelles, N. Bhoo Pathy, N. Calleja, N. Dimitrova, N. Eisemann, N. Larrañaga, N. Malila, N. Sanz, N. Wang, N. Zielonke, N.I. Somdyala, O. Ganry, O. Nimri, O.J. Ogunbiyi, P. Arveux, P. Baili, P. Contiero, P. Cueva, P. Finan, P. Grosclaude, P. Pavlou, P. Ricci, P. Sebastian, P. Sgargi, P. Torres, P. Zambon, P. Zhang, P.A. Jayalekshmi, P.C. De Souza, P.L. Giacciani, P.M. Walsh, Q.H. Huang, Q.L. Li, R. Alonso, R. Bayakly, R. Borchers, R. Capocaccia, R. Cesaraccio, R. Cusimano, R. De Angelis, R. Fita, R. Harewood, R. Lillini, R. Louchini, R. Marcos Gragera, R. Mężyk, R. Peris Bonet, R. Quinto, R. Rycroft, R. Sewpaul Sungkur, R. Stabenow, R. Stephens, R. Swaminathan, R. Swaminathan, R. Tessandori, R. Tumino, R. Zanetti, R.A. Asquez, R.A. Dewar, R.A. Rego, R.A. Tenney, R.C. Knowlton, R.D. Otto, R.I. Laue, R.J. Black, R.R. Woods, S. Bara, S. Bayo, S. Bouzbid, S. Busco, S. Delacour Billon, S. Demers, S. Eser, S. Felipe Garcia, S. Ferretti, S. Glaser, S. Góźdż, S. Khan, S. Koifman, S. Laronningen, S. Le Guyader Peyrou, S. Maspero, S. McPhail, S. Natsui, S. Park, S. Piffer, S. Rosso, S. Ryan, S. Sciacca, S. Siesling, S. Tuvshingerel, S. Wang, S. Wiangnon, S. Wright, S.A. Miles, S.D. Sapkota, S.G. Ibañez, S.H. Nortje, S.I. Dehler, S.L. Geater, S.M. Ess, S.M. Schwartz, S.P. Yang, S.Q. Huang, S.R. Zeissig, S.S. Manraj, S.T. Gershman, S.W. Bolick, T. Aareleid, T. Dal Cappello, T. Koike, T. Matsuda, T. Moran, T. Scuderi, T. Threlfall, T. Žagar, T.A. Janes, T.C. Tucker, T.S. Alexandre, U. Wojciechowska, V. Bouvier, V. Kumar, V. Pascucci, V.R. Mitter, VITARELLI, Susanna, W.D. Laspada, W.K. Mang, W.Q. Chen, W.W. Li, W: Oberaigner, X. Shen, X. Troussard, X.C. Wu, X.P. Gu, X.S. Wang, Y. Nishino, Y. Shen, Y. Verma, Y.H. Galán, Y.J. Won, Z. Valerianova, Z. Zaidi +495 morecore +1 more sourceCancer‐Like Fragmentomic Characteristics of Somatic Variants in Cell‐Free DNA
Advanced Science, EarlyView.We report that in non‐cancerous subjects, cell‐free (cfDNA) molecules harboring somatic variants exhibit cancer‐like fragmentomic characteristics associated with clonal hematopoiesis. Importantly, these somatic variant‐associated fragmentomic aberrations are more pronounced in cancer patients. Leveraging such somatic variant‐associated signals in cfDNA,Zhenyu Zhang, Yunyun An, Mengqi Yang, Yuqi Pan, Xiaoyi Liu, Fanglei Gong, Huizhen Lin, Bianbian Tang, Yunxia Bai, Xin Zhao, Yu Zhao, Changzheng Du, Kun Sun +12 morewiley +1 more sourceResolvin D5 Inhibits CXCL8 Expression in Colonic Epithelial Cells Through Activating GPR101 to Impede Neutrophil Recruitment and Consequently Alleviate Ulcerative Colitis
Advanced Science, EarlyView.RvD5 effectively alleviates UC by inhibiting STAT1 signaling to reduce CXCL8 expression in colonic epithelial cells via activation of GPR101, which subsequently decreases the infiltration of neutrophils in the colonic mucosal epithelium. Epimedin A1, a natural allosteric inhibitor of 5‐LOX, demonstrates potential as a therapeutic agent for UC by ...Pengxiang Guo, Yilei Guo, Yanrong Zhu, Ke Yan, Yulai Fang, Jiafeng Zhang, Yue He, Zhifeng Wei, Yufeng Xia, Yue Dai +9 morewiley +1 more sourceMR‐DELTAnet: A Longitudinal MRI‐Transformer Model Predicting Pathological Complete Response and Revealing Immune Microenvironment via scRNA‐seq in Locally Advanced Rectal Cancer
Advanced Science, EarlyView.The MR‐DELTAnet model utilizes longitudinal MRI to predict treatment response after neoadjuvant chemoradiotherapy in locally rectal cancer patients, accurately identifying patients likely to achieve pathological complete response for personalized management.Wuteng Cao, Huaxian Chen, Jiao Li, Yihui Zheng, Liqing Xie, Guozhong Xiao, Zeyan Wang, Fen Yuan, Junhong Chen, Chongbao Sun, Jing Dai, Jinping Zeng, Xinhua Wang, Lei Wu, Hongcheng Lin +14 morewiley +1 more sourcePhocaeicola coprophilus‐Derived 6‐Methyluracil Attenuates Radiation‐Induced Intestinal Fibrosis by Suppressing the IDO1‐Kynurenine‐AHR Axis
Advanced Science, EarlyView.IR‐induced dysbiosis depletes P. coprophilus and its metabolite 6‐methyluracil, leading to disinhibition of the IDO1‐Kyn‐AHR axis. This results in sustained fibroblast activation and collagen deposition, driving radiation induced intestinal fibrosis. ABSTRACT
Therapeutic options for radiation‐induced intestinal fibrosis (RIF) remain limited. This study Jiaxin Zhang, Zhen Wang, Shuang Li, Chao Luo, Han Li, Shengjie Ma, Pai Wang, Heshi Liu, Lijun Sun, Yue Yin, Weizhen Zhang, Quan Wang +11 morewiley +1 more source