Results 181 to 190 of about 5,139,728 (295)
Advanced NanoBiomed Research, EarlyView.This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari +5 more
wiley +1 more source
A rectal cancer organoid platform to study individual responses to chemoradiation
Nature Medicine, 2019 K. Ganesh +51 more
semanticscholar +1 more source
Polyphenol‐Based Biomaterials Against Cancer Radio/Chemotherapy‐Induced Intestinal Toxicity
Advanced NanoBiomed Research, EarlyView.Radiotherapy/chemotherapy often causes intestinal toxicity, impairing cancer patients’ quality of life and treatment efficacy. Polyphenols protect against this injury via multiple mechanisms, but face oral use limitations. This review outlines their protective mechanisms and delivery challenges, highlighting recent oral delivery advances and future ...
Jixu Lu +4 more
wiley +1 more source
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT Gastrointestinal cancers (GICs) constitute one of the leading causes of cancer‐related morbidity and mortality worldwide. Despite currently available therapeutic strategies, new approaches and procedures are needed for their prevention and treatment.
Raúl Vergara +5 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Predetermined treatment duration limits (PTDLs) are often used by Taiwan's National Health Insurance Administration to contain healthcare costs, but they may compromise patient outcomes. Therefore, we studied Taiwan's 2017 extension of the bevacizumab PTDL from 24 to 36 weeks in metastatic colorectal cancer (mCRC) to evaluate whether prolonged ...
Wei‐Ming Huang +6 more
wiley +1 more source
Liver Transplantation, EarlyView., 2022 Abstract Hepatopulmonary syndrome (HPS) is associated with increased waitlist mortality in liver transplantation (LT) candidates. Children with HPS are granted Model for End‐Stage Liver Disease (MELD)/Pediatric End‐Stage Liver Disease (PELD) exception points for waitlist prioritization in the United States based on criterion developed for adults.
Muhammad H. Raza +8 more
wiley +1 more source
Public Perceptions of Marital Rape: Does Level of Force Used Have an Impact?
Behavioral Sciences &the Law, EarlyView.ABSTRACT Research indicates that marital rape is viewed by the public as less harmful to a victim than stranger/acquaintance rape. The aim of the study is to extend the research conducted by Robinson in 2017, investigating how levels of force influence perceptions of marital rape.
Leanne Hanney, Amy Shelford, Andy Guppy
wiley +1 more source
International Journal of General MedicineYaoli Liu,1 Haimei Lun,1,2 Xuanzhang Huang,1 JianYuan Huang,1 Shangyong Zhu1 1Department of Medical Ultrasound, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People’s Republic of China; 2Department of Ultrasound, People’s
Liu Y, Lun H, Huang X, Huang J, Zhu S
doaj
The multidisciplinary management of rectal cancer
Nature reviews: Gastroenterology & hepatology, 2020 D. S. Keller +4 more
semanticscholar +1 more source
Chemistry – A European Journal, EarlyView.ABSTRACT Fluorouracil‐platinum(IV) prodrugs represent a novel class of multimechanistic chemotherapeutics with enhanced anticancer potential. The prodrugs PtIVP‐5FUMeOBut and PtIV56‐5FUMeOBut were actualized by derivatising the clinical drug 5‐fluorouracil (5FU) and coordinating it to platinum(IV) complexes, leveraging the established cytotoxicity of ...
Maria George Elias +9 more
wiley +1 more source