The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP‐1 Signaling in Colorectal Cancer
Advanced Science, EarlyView.In wild‐type intestinal epithelial cells, KDM6B demethylates SLC10A2 to promote its expression, after which SLC10A2 suppresses ERK phosphorylation, inhibiting AP‐1 (Fos/Jun) transcription and chemokine production. In KDM6B‐deficient intestinal epithelial cells, SLC10A2 methylation increases, and its expression decreases.
Zhibo Hu +16 more
wiley +1 more source
Cáncer rectal diagnosticado tras profilaxis de tromboembolia venosa poscirugía ortopédica con dabigatran [PDF]
, 2021 Ricardo Guardado-Beltrán +3 more
openalex +1 more source
PLoS ONEBackgroundLLNM can occur in mid-low rectal cancer, but LLND in patients with rectal cancer presents certain challenges. Recent years have seen the progressive application of ICG fluorescence imaging technology in colorectal surgery.
Chu-Ying Wu, Wen-Jin Zhong, Kai Ye
doaj +1 more source
Advances in Multidisciplinary Treatment of Rectal Cancer
Cancer Biology & Medicine, 2009 To summarize the advances in the multidisciplinary treatment of rectal cancer and to analyze the existing problems and development prospects. The full text database retrieval system of MEDLINE and the periodicals of CHKD were searched.
Changlin ZHAO, Hongqin SUN, Yang YANG
doaj +1 more source
El drenaje pélvico en la escisión total del mesorrecto, un estudio multicéntrico paneuropeo [PDF]
, 2017 Antecedents. Aunque existe un buen nivel de evidencia respecto a la inefectividad de la colocación de un drenaje pélvico profiláctico después de las cirugías de resección de colon, todavía existe controversia en las cirugías de escisión del mesorrecto ...
de la Rosa Estadella, Marta +1 more
core
Advanced Science, EarlyView.Corticosteroids improve the efficacy of immune checkpoint blockade therapy in metastatic murine breast cancer. By normalizing the tumor immune microenvironment, corticosteroids reduce immunosuppressive signals, restore T‐cell function, and promote antitumor immune responses, resulting in enhanced tumor control.
John D. Martin +19 more
wiley +1 more source
Rectosigmoid Cancer-Rectal Cancer or Sigmoid Cancer? [PDF]
Am J Clin Oncol, 2022 Hui C +10 more
europepmc +1 more source
Relación de la susceptibilidad genética y de las características anatomopatológicas del cáncer de próstata con los polimorfismos de nucleótido simple [PDF]
, 2012 Actualmente no se disponen de marcadores biológicos específicos para la cáncer de próstata produciéndose en muchas ocasiones biopsias prostáticas innecesarias o un sobretratamientos para cánceres indolentes.
Ruiz Domínguez, Jose Manuel +2 more
core
A20 Facilitates Oxaliplatin Sensitivity in Colorectal Cancer Through Monoubiquitylation of IKK‐β
Advanced Science, EarlyView.This study demonstrates that the expression of A20, a ubiquitin‐editing enzyme, is positively correlated with oxaliplatin sensitivity in colorectal cancer (CRC). Mechanistically, A20 enhances oxaliplatin sensitivity by inhibiting NF‐κB nuclear translocation through monoubiquitination of IKK‐β.
Fan Luo +12 more
wiley +1 more source
EVALUACIÓN DE RESULTADOS QUIRÚRGICOS DESDE LA PERSPECTIVA DEL PACIENTE [PDF]
, 2009 RESUMENMedir la calidad de vida relacionada a salud y los síntomas de los pacientes es un problema difícil. Las medición de los problemas de salud mediante escalas o cuestionarios se ha desarrollado para crear los Instrumentos de Evaluación desde la ...
Biemond, Bart J +11 more
core +2 more sources