RvD5 effectively alleviates UC by inhibiting STAT1 signaling to reduce CXCL8 expression in colonic epithelial cells via activation of GPR101, which subsequently decreases the infiltration of neutrophils in the colonic mucosal epithelium. Epimedin A1, a natural allosteric inhibitor of 5‐LOX, demonstrates potential as a therapeutic agent for UC by ...
Pengxiang Guo +9 more
wiley +1 more source
Radioterapia adyuvante en el cáncer rectal
Introduction: radiotherapy is used as a treatment for more than a century and it is based on the use of local ionizing radiation. Objective: To evaluate the response to adjuvant radiotherapy in patients with rectal cancer.
Lissi Lisbet Rodríguez Rodríguez +5 more
doaj
TCF7 transcriptional activation of MACC1 regulates aerobic glycolysis and promotes oxaliplatin resistance in rectal cancer [PDF]
Background and purpose: Rectal cancer occurs on the inner wall of the rectum, and metastasis-associated in colon cancer 1 (MACC1) can promote drug resistance in colon cancer cells.
YAN Yan, ZHOU Liqing, XIA Jianhong, MA Tingting
doaj +1 more source
Sangrado rectal tras la administración de Dabigatrán [PDF]
Presentamos el caso de tres pacientes intervenidos de prótesis total de cadera, que tras la administración protocolaria de tromboprofilaxis con Dabigatrán, presentaron un sangrado rectal importante, siendo este la primera manifestación de un cáncer ...
Díaz de Rada, P. +2 more
core
ETV4 coordinates a dual transcriptional program by upregulating MET and asparagine synthetase (ASNS). The resulting asparagine (Asn) secretion acts as a metabolic signal, reprogramming hepatic stellate cells (HSCs) and primary cancer‐associated fibroblasts (CAFs) toward an inflammatory phenotype. These activated stromal cells release HGF to sustain the
Dujiang Fu +14 more
wiley +1 more source
Diagnosis, treatment and full-process surveillance of early rectal cancer [PDF]
Early rectal cancer is defined as any size of rectal epithelial tumor with infiltration depth limited to the mucosa and submucosa, regardless of with or without lymph node metastasis.
LAN Ping, CHEN Yongle, HE Xiaosheng
doaj +1 more source
Association between irrigation fluids, washout volumes and risk of local recurrence of anterior resection for rectal cancer: a meta-analysis of 427 cases and 492 controls. [PDF]
BACKGROUND: Rectal washout can prevent local recurrence after anterior resection of rectal cancer. Few studies have focused particularly on the association between irrigation fluids volume or agents and the risk of local recurrence after anterior ...
Can Zhou +6 more
doaj +1 more source
Neoadjuvant radiotherapy for rectal cancer management
Thirty per cent of all colorectal tumours develop in the rectum. The location of the rectum within the bony pelvis and its proximity to vital structures presents significant therapeutic challenges when considering neoadjuvant options and surgical ...
G. Feeney +6 more
semanticscholar +1 more source
Prostatectomía radical de salvamento en cáncer de próstata radioresistente [PDF]
La prostatectomía radical de salvamento viene siendo usada como tratamiento con intención curativa en aquellos pacientes que cursan con recaída bioquímica local luego de radioterapia1.
Cuadrado Jiménez, Neider +1 more
core
Differential miRNA expression profiling reveals miR-205-3p to be a potential radiosensitizer for low- dose ionizing radiation in DLD-1 cells [PDF]
Indexación: Scopus.Departamento de Oncología Básico-Clínica, Facultad de Medicina, Universidad de Chile, Santiago, Chile 2Comisión Chilena de Energía Nuclear, Santiago, Chile 3Center for Research and Applications in Plasma Physics and Pulsed Power, P4 ...
Andaur, R. +5 more
core +1 more source

