Results 41 to 50 of about 225,356 (198)
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Levantamento pedológico semidetalhado (1:25.000) da microbacia da Água Três Unidos, Município de Vera Cruz (SP). [PDF]
, 2017 Este trabalho é um relato dos solos identificados no levantamento pedológico semidetalhado da microbacia da Água Três Unidos. Abrangendo aproximadamente 1.624 hectares, a microbacia situa-se no município de Vera Cruz, localizada a oeste do Estado de São ...
BERTOLANI, F. C. +3 more
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Estudo de solos do município de Inhacorá - RS. [PDF]
, 2014 bitstream/item/41485/1/Inhacora.pdf; bitstream/item/41487/1/mapa-aptidao.pdf; bitstream/item/41489/1/mapa-capacidade.pdf; bitstream/item/41491/1/mapa-relevo.pdf; bitstream/item/41492/1/mapa-solos ...
CUNHA, N. G. da +7 more
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Distribuição do Mg2+, Ca2+, Al3+ em solos adicionados de óxido de magnésio em condições de laboratório. [PDF]
, 2013 bitstream/item/76247/1/BPD-197-Oxido-magnesio ...
ANDRADE, C. C. +7 more
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Efeito da inundação sobre as propriedades de um gleissolo salico sodico de várzea do rio dos Morcegos, no município de Primavera, PA. [PDF]
, 2011 bitstream/item/34346/1/ORIENTAL-BP21 ...
BOTELHO, S. M., FERREIRA, W. de A.
core +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Solos cultivados com cajueiro: características e limitações. [PDF]
, 2011 Visando caracterizar e classificar os solos utilizados com cajueiro nas principais regioes produtoras, assim como determinar as limitacoes existentes para a cultura e edefinir os parametros de avaliacao da aptidao agricola da terra para cajueiro, o CNPAT,
FROTA, P. C. E. +3 more
core