Results 41 to 50 of about 238,960 (237)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Transporte acrópeto de cátions em mudas de videira cultivadas em condições salinas. [PDF]

, 2019
O objetivo deste trabalho foi estudar o transporte acrópeto de cátions em quatro porta-enxertos de videira de tolerância diferenciada ao estresse salino e em duas variedades copas, bem como a sua viabilidade para estudo de discriminação de videiras ...
SILVA, D. J., ARAÚJO, C. A. de S., GROSSI, F., COSTA, W. P. L. B. da   +3 more
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Soma de bases e capacidade de troca de cátions como indicadores de qualidade química do agroecossistema com mangueiras. [PDF]

, 2018
O objetivo deste trabalho foi avaliar a influência do manejo do solo e do uso da adubação verde na qualidade química do solo, utilizando-se como atributos soma de base e capacidade de troca de cátions, em agrossistema de cultivo da mangueira no ...
SILVA, D. J., BRITO, M. I. C. de, GONÇALVES, M, SILVA, V. C. da, GIONGO, V.   +4 more
core  

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Covalent organic framework membranes for efficient separation of monovalent cations

Nature Communications, 2022
Membrane technology holds great promise in separating monovalent cations but the sub-nanometer ion size and the small difference in ion size makes separation of monovalent cations a challenging task. Here, the authors demonstrate the efficient separation
Hongjian Wang, Yeming Zhai, Yang Li, Yu Cao, Benbing Shi, Runlai Li, Zingting Zhu, Haifei Jiang, Zheyuan Guo, Meidi Wang, Long Chen, Yawei Liu, Kai-Ge Zhou, Fusheng Pan, Zhongyi Jiang   +14 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Absorção de cátions e ânions pelo capim-coastcross adubado com uréia e nitrato de amônio. [PDF]

, 2014
Os processos fisiol6gicos das plantas são afetados pelo balanço de cátions e ânions absorvidos. O objetivo deste trabalho foi determinar a absorção de cátions e ânions quando plantas de capim-coastcross receberam doses elevadas de nitrogenio.
SILVA, A. G. DA, PRIMAVESI, A. C., PRIMAVESI, A. C. P. de A., PRIMAVESI, O., CORRÊA, L. de A., SILVA, A. G., CANTARELLA, H., PRIMAVESI, O. M. A. S. P. R.   +7 more
core  

Ligand Mediated Metal Cations Exchanges within Metallo‐Dynameric Solid Films

ChemistryOpen, 2019
Dynameric solid films may be generated via the adequate imine‐bond connection between bis(pyridine‐2,6‐diimine) core centres, coordinated with different metal cations and diaminoPEG connectors.
Dr. Yan Zhang, Dr. Mihail Barboiu
doaj   +1 more source