Results 101 to 110 of about 3,585,369 (296)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Metabólitos secundários presentes na Annona muricata L e suas propriedades nutricionais e funcionais em oncologia

open access: yesRevista Brasileira de Obesidade, Nutrição e Emagrecimento, 2017
A nutrição funcional tem ganhado espaço nos últimos anos por sua ação terapêutica, com destaque para o fruto graviola. Vários estudos bem conduzidos sugerem que o fruto possui quantidades consideráveis de minerais, fibras, compostos antioxidantes e ...
Erlania Carmo Freitas   +2 more
doaj  

Autocuidado e apoio social em mulheres do Núcleo Mama Porto Alegre [PDF]

open access: yes, 2014
Breast cancer is one the most prevalent types of cancer among women. Many causes are known, ranging from the biological to the psychosocial. In Rio Grande do Sul, especially in Porto Alegre, occurrence rates and fatalities due to breast cancer are some ...
Hermel, Júlia Schneider
core  

Evaluación de la calidad de vida de pacientes oncológicos en tratamiento quimioterápico complementar [PDF]

open access: yes, 2008
Estudo do tipo exploratório descritivo que objetivou avaliar a qualidade de vida de pacientes com câncer de mama e intestino, no início e três meses após o tratamento quimioterápico.
MACHADO, Sheila Mara   +1 more
core   +2 more sources

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

open access: yesMolecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo   +8 more
wiley   +1 more source

Abordagem da criança em situações especiais [PDF]

open access: yes, 2014
Aborda os cuidados de pós-operatório domiciliar em crianças, bem como as neoplasias mais frequentes em pediatria, seus sinais e sintomas de alerta para avaliação, as formas de manejo domiciliar e referenciamento.
Universidade Federal do Maranhão - UNA-SUS/UFMA
core  

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

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