Results 141 to 150 of about 343,141 (245)

Capture and Culture of Circulating Tumor Cells Using a Biodegradable 3D Scaffold for Patient‐Derived Xenograft Construction

open access: yesAdvanced Science, EarlyView.
A self‐supporting, biocompatible, and biodegradable 3D cellulose scaffold has been developed for efficient isolation and in situ expansion of circulating tumor cells (CTCs) from patient blood. Subsequently, the 3D cellulose scaffold with cultured CTCs is directly implanted into immunodeficient mice for constructing patient CTC‐derived xenograft (CDX ...
Yi‐Ke Wang   +9 more
wiley   +1 more source

The predictive value of miR-29b-2-5p on the prognosis of cervical cancer and its inhibitory effect on cervical cancer progression

open access: yesThe International Journal of Biological Markers
Objective The poor prognosis of cervical cancer patients leads to an annual increase in mortality, while microRNAs are involved in various cancers, including cervical cancer.
Qinghan Liu   +6 more
doaj   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

open access: yesAdvanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li   +12 more
wiley   +1 more source

The Effects of Hysterectomy on Urinary and Sexual Functions of Women with Cervical Cancer: A Systematic Review. [PDF]

open access: yesRev Bras Ginecol Obstet, 2022
Firmeza MA   +5 more
europepmc   +1 more source

Beyond Catalytic Therapy: Copper‐Paeonol Nanozymes Disrupt Fascin‐Mediated Actin Bundling to Suppress Tumor Growth and Metastasis

open access: yesAdvanced Science, EarlyView.
Copper‐paeonol nanozymes target tumor‐specific reactive oxygen species generation and disrupt fascin‐mediated actin bundling, effectively suppressing tumor growth and metastatic colonization. Abstract Fascin, an actin‐bundling protein universally upregulated in metastatic tumors, drives tumor migration and invasion by promoting filopodia and ...
Peiying Zhang   +8 more
wiley   +1 more source

Papilomavírus humano

open access: yesDST, 1999
Em vista dos recentes avanços da biologia molecular e da importância que estas mudanças representaram no entendimento da gênese e regulação das neoplasias, particularmente aquelas da cérvice uterina, os autores fazem uma atualização dos conceitos que ...
Ana K. Gonçalvez   +4 more
doaj  

A intervenção dos terapeutas da fala na área oncológica [PDF]

open access: yes, 2008
Com este artigo pretendemos dar ênfase a novas áreas de intervenção dos Terapeutas da Fala, que estão muito para além das tradicionalmente atribuídas a estes profissionais, decorrentes de diversas intervenções cirúrgicas em indivíduos portadores de ...
Monteiro, Eurico   +1 more
core  

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

open access: yesAdvanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto   +11 more
wiley   +1 more source

Epigenetic mechanisms associated with progression, prognosis, and new treatment strategies for metastatic cervical squamous cell carcinoma

open access: yesBasic & Clinical Cancer Research
Background: In the 21st century, the main cause of death in both sexes worldwide are cardiovascular diseases, in second place are neoplasms. In the case of women, the fourth cause of mortality is breast cancer despite the screening.
Josué Mondragón-Morales   +3 more
doaj   +1 more source

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