Results 141 to 150 of about 10,776,501 (260)
A VDAP‐programmed liquid‐crystalline depot enables pH‐responsive postoperative immunotherapy for triple‐negative breast cancer. VDAP stabilizes a leakage‐resistant HII mesophase through peptide–lipid electrostatic assembly, whereas tumor acidosis unlocks the matrix and promotes graded topology remodeling toward a bicontinuous Im3̄m cubic phase for ...
Yan Yan +12 more
wiley +1 more source
Large Oncosomes Induce Pro‐Metastatic Stromal‐Myeloid Reprogramming
Large oncosomes systemically reprogram bone marrow mesenchymal stem cells through innate nucleic acid sensing, driving inflammatory and immunosuppressive remodeling that supports a metastasis‐permissive bone marrow environment, revealing a novel tumor‐host communication axis in cancer. ABSTRACT Bone metastasis can be facilitated by systemic remodeling,
Taylon Felipe Silva +18 more
wiley +1 more source
A carrier‐free peptide‐guided PSP@IR‐CF3 nanofiber system integrates PD‐L1 targeting and photothermal immunotherapy for enhanced cancer treatment. By revealing PTIT‐induced activation of the HSP70/AKT/mTOR pathway and incorporating mTOR inhibition, this strategy effectively overcomes therapeutic resistance and prevents tumor recurrence, providing a ...
Xinyu Zhang +11 more
wiley +1 more source
CÂNCER DE MAMA: A POSSIBILIDADE DA DETECÇÃO PRECOCE
Os elevados índices de incidência e mortalidade por câncer de mama no Brasil justificam a implementação de ações nacionais voltadas para a prevenção e o controle do câncer.
HENRIQUE O. LAUER BARTH +1 more
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GINCANA ROSA: ESTRATÉGIA PARA A PREVENÇÃO DO CÂNCER DE MAMA
Introdução: O câncer de mama é uma das principais neoplasias que atingem a população feminina, sendo fundamental o desenvolvimento de estratégias de prevenção.
UFPE +3 more
core
Bacteria residing within tumor cells contribute to breast cancer progression, but few therapies target their elimination. FeSe2 nanosheets coated with cancer cell membranes accumulate in tumors and generate reactive oxygen species under ultrasound, killing tumor cells and their harbored bacteria at the same time.
Xiaojing Leng +8 more
wiley +1 more source
O conhecimento e a prática de mamografia em mulheres residentes em Florianópolis/SC: estudos de base populacional [PDF]
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Saúde Coletiva, Florianópolis, 2013O objetivo deste trabalho é descrever o conhecimento e a prática de mamografia e identificar os ...
Schneider, Ione Jayce Ceola
core
This study presents a label‐free spectroscopic platform to evaluate membrane protein conformation on patient‐derived glioblastoma cell membrane‐coated magnetic nanovectors. This work demonstrates that preserving membrane protein integrity during nanoparticle fabrication enhances homotypic tumor targeting and reduces hard protein corona formation ...
Daniele De Pasquale +16 more
wiley +1 more source
Click chemistry has evolved from making covalent connections to also breaking bonds. Here, a cascade assembly is reported that combines these maneuvers to build multifunctional biomolecular scaffolds in a modular one‐pot reaction. The unifying azide release‐tetrazine hub clicks with a trans‐cyclooctene tag, rapidly liberates N,N‐dimethylaniline to ...
Markus Staudt +9 more
wiley +1 more source
Câncer de mama: da descoberta à recorrência da doença
Estudo exploratório e descritivo que objetivou compreender o sentimento da mulher mastectomizada desde o diagnóstico até a possibilidade da recorrência do câncer de mama, desenvolvido com 15 mulheres com as idades compreendidas entre 30 a 75 anos ...
Luana de Sousa Pinho +3 more
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