Results 91 to 100 of about 36,094 (222)

Single‐Cell Morphomechanics of Prostate Cancer‐Associated Fibroblasts Identifies Distinct Features Associated with Patient Outcome

Advanced Science, EarlyView.
Cancer‐associated fibroblasts (CAFs) in prostate tumors exhibit distinct morphomechanical traits vs normal fibroblasts, including greater stiffness and volume, more elongated stress fibres, and larger and more elongated nuclei. These features, quantified through imaging and real‐time deformability cytometry, correlate with patient outcomes and can be ...
Antje Garside, Angela Jacobi, Shivakumar Keerthikumar, Vaibhav Mahajan, Michelle Richards, Birunthi Niranjan, Linda Teng, Nicholas Choo, Johannes Low Jun Wei, Gail P Risbridger, Mitchell G Lawrence, Anna V. Taubenberger   +11 more
wiley   +1 more source

New Cardiovascular Biomarkers in Breast Cancer Patients Undergoing Doxorubicin-Based Chemotherapy. [PDF]

Arq Bras Cardiol, 2023
Pestana RMC, Silvino JPP, Oliveira AN, Soares CE, Sabino AP, Simões R, Gomes KB.   +6 more
europepmc   +1 more source

Movimento Cascavel Rosa - Na luta contra o câncer [PDF]

, 2014
Trabalho apresentado no 31º SEURS - Seminário de Extensão Universitária da Região Sul, realizado em Florianópolis, SC, no período de 04 a 07 de agosto de 2013 - Universidade Federal de Santa Catarina.A Organização Mundial da Saúde estima que, por ano ...
Berto, Gerti, Côrtes, Simone, Hirata, Francielle, Lara, Aline, Martins, Adriane, Oenning, Micheli, Schmitt, Vera, Schons, Raquel, Silva, Heloisa, Souza, Roberto, Verli, Claudecir   +10 more
core  

The OtR tumor recurrence and metastasis model reveals doxorubicin‐induced tumor shrinkage doesn't guarantee prolonged survival

Animal Models and Experimental Medicine, EarlyView.
Tumor growth inhibition does not predict survival benefit in a clinically relevant metastasis model. Tumor local growth and systemic metastasis represent distinct biological processes. In the 4T1‐OtR model, although chemotherapy significantly suppresses primary tumor growth, it fails to prevent distant metastasis or extend overall survival.
Lingli Luo, Ling Liu, Minyao Deng, Yong Jiang, Chuan Liu, Xiang Chen, Xiaoxi Li   +6 more
wiley   +1 more source

[Construction and validation of a video about breast cancer for deaf womenConstrucción y validación de un video sobre el cáncer de mama para mujeres sordas]. [PDF]

Rev Cuid, 2023
Pereira-Gomes JD, Tomaz-De-Carvalho A, Sousa-Albuquerque-Brandao MG, Galindo-Neto NM, Do-Livramento-Fortes-Figueiredo M, Ribeiro Mariano-Grimaldi M.   +5 more
europepmc   +1 more source

Trametinib in Adults with Neurofibromatosis Type 1‐Related Symptomatic Plexiform Neurofibromas

Annals of Neurology, EarlyView.
Objective Mitogen‐activated protein kinase kinase inhibitors have shown promising results in treatment of plexiform neurofibromas in neurofibromatosis type 1 patients, but data in adults are limited. The aim of this phase 2 study was to investigate the efficacy and safety of trametinib in adults with neurofibromatosis type 1.
D. Christine Noordhoek, David F. Hanff, Pim J. French, Sarah A. van Dijk, Erik A.C. Wiemer, Olivier C. Manintveld, Martin J. van den Bent, Walter Taal   +7 more
wiley   +1 more source

Interações entre fatores de crescimento (GFs) e o receptor de progesterona (PR) em câncer de mama [PDF]

, 2011
En trabajos previos hemos demostramos la existencia de interacciones bi-direccionales entre las vías de los progestá- genos y de la heregulina (HRG) en cáncer mamario.
Balaña, Maria Eugenia, Beguelin, Wendy, Carnevale, Romina Paula, Charreau, Eduardo Hernan, Díaz Flaqué, María Celeste, Elizalde, Patricia Virginia, Labriola, Leticia, Proietti Anastasi, Cecilia Jazmín, Salatino, Mariana, Schillaci, Roxana   +9 more
core  

Mannose‐Modified Cationic Liposome‐Based mRNA Therapeutics for Improved Triple‐Negative Breast Cancer Immunotherapy

Advanced NanoBiomed Research, EarlyView.
Schematic illustration of mTEM8‐loaded cationic liposome (cLipo‐Man/mTEM8) therapeutics for improved triple‐negative breast cancer immunotherapy. Despite triple‐negative breast cancer (TNBC) is the most heterogeneous and aggressive subtype of breast cancer, immunotherapy is emerging as a promising therapy.
Kexin Deng, Juping Sun, Junyu Liu, Yuqi Zhang, Wanwan Liu, Xiaobin Li, Han Wu, Juan Li, Jisong Zhang, Chanyuan Jin, Can Yang Zhang   +10 more
wiley   +1 more source

Cuidado humanizado na área da saúde [PDF]

, 2018
Nós profissionais de saúde estamos tradicionalmente mais vinculados ao humanismo em relação à outras disciplinas, por nossa formação e porque trabalhamos de maneira muito direta com doentes, além de termos que criar contextos que sirvam como pontes para ...
GOMEZ TORRES, DANELIA, GOMEZ TORRES, DANELIA   +1 more
core  

Myo‐Inositol Mitigates Oxidative Stress in Bovine Mammary Epithelial Cells via Activation of the SIRT5/Nrf2 Signaling Axis

Animal Research and One Health, EarlyView.
Myo‐inositol alleviates oxidative stress in dairy cow mammary epithelial cells via the Sirt5/Nrf2 pathway to promote mitochondrial fusion. This graphical abstract was created with BioRender.com. ABSTRACT High‐yielding dairy cows are susceptible to mammary gland oxidative stress due to prolonged intensive lactation, leading to redox imbalance.
Yufei Zhang, Yu Cao, Meng Zhang, Huijie Hu, He Ma, Junlong Bi, Juxiong Liu, Shoupeng Fu, Wenjin Guo   +8 more
wiley   +1 more source