Results 81 to 90 of about 39,920 (269)

Stress e coping no período perioperatório de câncer de mama Estrés y Sobrellevar en el período perioperatorio de cáncer de mama Stress and copong in perioperative period of breast cancer

Revista da Escola de Enfermagem da USP, 2009
Este trabalho é uma revisão bibliográfica, que objetiva refletir sobre stress e coping no perioperatório de câncer de mama, realizada em bases de dados on-line nacionais, abrangendo trabalhos publicados de 1996 a 2006. Foram encontrados 63 artigos, sendo
Rafaela Andolhe, Laura de Azevedo Guido, Estela Regina Ferraz Bianchi   +2 more
doaj   +1 more source

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

Advanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su, Ting‐Chun Chou, Maria Teresa López‐Cascales, Junfeng Huang, Tsai‐Ying Chen, Sjoukje van Wieren, Chan Li, Cecile Beerens, Li You, Jelle Storteboom, Miao‐Ping Chien   +10 more
wiley   +1 more source

Genética e câncer de mama

Clinical and Biomedical Research, 2022
É sabido que o câncer de mama, assim como a maioria dos cânceres, faz parte de um grupo de doenças conhecidas como multifatoriais, nas quais fatores etiológicos múltiplos – genéticos e ambientais – interagem, de formas variadas e ainda não totalmente ...
Sandra L. Segal, Ana Cristina Bittelbrunn, Jorge V. Biazús, Carlos H. Menke, José A. Cavalheiro, Nilton L. Xavier, Eliane G. Rabin, Rodrigo Cericatto   +7 more
doaj  

Estudo descritivo da mortalidade por doenças crônicas utilizando dados secundários do sistema de informções sobre mortalidade (SIM) [PDF]

, 2014
Anais do III Encontro de Iniciação Científica da Unila - Sessão de Saúde Coletiva e Biologia I - 07/11/14 – 08h30 às 11h10 - Unila-PTI – Bloco 03 – Espaço Mercosul – Sala 06No Brasil, o câncer representa a segunda causa de óbito na população adulta ...
Gamarra, Carmen Justina, Santos, Andreia Pereira dos, Sibim, Alessandra Cristiane   +2 more
core  

An Artificial Antibody‐Based Toolbox Accelerates Validation of Hidden Microproteins Encoded by the Dark Genome

Advanced Science, EarlyView.
Microproteins are hidden treasures encoded by the “dark proteome” but remain largely underexplored due to the lack of highly efficient tools. We developed a molecularly imprinted polymers (MIPs)‐based toolbox (CLAIMID) to achieve accelerated and ultrasensitive microproteins validation at multiple biological scales (single living cells, cell populations,
Hui He, Anqi Zhang, Zhanchen Guo, Qi Li, Song Gao, Wenyan Guan, Ying Li, Jingran Chen, Sijia Sun, Jian He, Zhen Liu   +10 more
wiley   +1 more source

A pilot study of the effects of hormone therapy on normal breast tissue of postmenopausal women [PDF]

, 2006
PURPOSE: to analyze breast tissue of postmenopausal women before and after six months of continuous combined estrogen-progestin replacement therapy (0.625 mg conjugated equine estrogens associated with 2.5 mg medroxyprogesterone acetate).
Baracat, Edmund Chada, Dardes, Rita de Cássia de Maio, Elias, Simone, Heinke, Thais, Kemp, Claudio, Lima, Geraldo Rodrigues de, Waitzberg, Angela Flávia Logullo   +6 more
core   +3 more sources

Highly Active Cu14 Cluster Precisely Activates Autophagy Inhibitor to Amplify Cuproptosis Immunotherapy

Advanced Science, EarlyView.
An atomically precise Cu14 cluster‐mediated bond scission reaction pioneers the amplification of the antitumor immune response via synergetic cuproptosis‐associated immunogenic cell death induction and in situ autophagy blockade. ABSTRACT Transition metal‐mediated cleavage mechanisms have emerged as an effective means to mitigate the off‐target ...
Qiu‐Xu Zang, Wei‐Tong Chen, Yu‐Ying Shen, Zhao‐Yang Wang, Kai Li, Xueli Zhao, Yanjuan Sang, Xiaoyuan Chen, Shuang‐Quan Zang   +8 more
wiley   +1 more source

Prevenção na escola: IMAMA e NUDEC no IFRS Bento Gonçalves [PDF]

, 2014
Trabalho apresentado no 31º SEURS - Seminário de Extensão Universitária da Região Sul, realizado em Florianópolis, SC, no período de 04 a 07 de agosto de 2013 - Universidade Federal de Santa Catarina.Com o intuito de conscientizar a comunidade a ...
Anhaia, Elisa, Brum, Felipe, Cattani, Nicole, Corso, Emanuele, Dein, Eduarda, Delazeri, Amanda, Dobner, Andrei, Dors, Monique, Faganello, Alexandre, Giacomazzi, Elizabethe, Jahn, Danaila, Kirchhof, Ana Claudia, Neckel, Djennifer, Padovani, Brenda, Padovani, Karen, Possa, Bruno, Pozzobon, Leonardo, Rodrigues, Jonas, Rosa, Dienefer, Sampaio, Maira, Santos, Michele, Sauthier, Lorete, Silva, Rafael, Somavilla, LuanaMaria, Tomazel, Ketlin, Weber, Aline, Zandoná, Susana, Zanon, Gabriel, Zuchi, Tais   +28 more
core  

Engineered Bacteria Factory Integrating Drug Delivery and Antibody Manufacture for Activating the STING Signal Pathway Mediated Tumor Immunotherapy

Advanced Science, EarlyView.
To address the limitations of protein‐based ICIs in applications, this study constructed an engineered bacterium, HRB, capable of expressing aCD47 in hypoxic TME. Through the Schiff base reaction, responsive liposomes (LC) loaded with the STING agonist cGAMP were connected to the surface of bacteria to form HRB@LC.
Peng‐Shuo Dong, Tian Yao, Yong Li, Zi‐Hui Yan, Xiao‐Ting Xie, Jia‐Hua Zou, Kai Cheng, Jin‐Xuan Fan, Yuan‐Di Zhao, Qiu‐Ran Xu   +9 more
wiley   +1 more source

Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis

Advanced Science, EarlyView.
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason, Anindya Sen, Suhan Cho, Se Jong Lee, Keyata Thompson, Md Musavvir Mahmud, Poornima Dubey, Talia Guardia, Anthony Kim, Stuart Martin, Nathan Wright, Konstantinos Konstantopoulos, Aikaterini Kontrogianni‐Konstantopoulos   +12 more
wiley   +1 more source