Results 191 to 200 of about 58,993,052 (257)

[Breast cancer: suspicious findings on mastography associated with the histopathological result]. [PDF]

open access: yesRev Med Inst Mex Seguro Soc
Zambrano-Terrazas SP   +5 more
europepmc   +1 more source

Design of an In Vivo‐Like Phantom for Quantitative Body CEST MRI

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To design and validate a reproducible in vivo‐like fat‐containing CEST phantom that enables robust quantitative CEST MRI for body applications by providing physiologically realistic relaxation properties, relevant endogenous CEST contrasts (amide, guanidino, rNOE, and semi‐solid MT), and a controlled fat component.
Petr Menshchikov   +5 more
wiley   +1 more source

Proteomic Analysis of Mixed Cell Membrane Extracts From Triple‐Negative Breast Cancer Cell Lines Revealed Broad Metabolic Reprogramming Associated With Tumor Progression

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) represents the most aggressive subtype with limited therapeutic options and the poorest clinical outcomes. Using high‐resolution nUPLC‐QTOF‐MS/MS, we performed comprehensive proteomic profiling of TNBC cell lines representing disease progression stages: HCC‐1937 (stage IIB), HCC‐1599 (stage IIIA), and MDA ...
Claudia Sissely Chaviano‐Montes de Oca   +7 more
wiley   +1 more source

Genetic screening of FFPE breast cancer biopsies for the <i>BRCA1</i>-185delAG mutation in Trinidad and Tobago. [PDF]

open access: yesRev Panam Salud Publica
Abrahim SC   +9 more
europepmc   +1 more source

Subtype‐specific prognostic relevance of IL6 in basal‐like breast cancer and modulation of IL6 expression by nanobacteria‐like particles in MDA‐MB‐231 cells

open access: yesPrecision Medical Sciences, EarlyView.
High IL6 expression correlates with shorter relapse‐free survival in the basal‐like breast cancer subtype. Nanobacteria‐like particles (NB‐LPs) significantly reduce breast cancer cell viability and IL6 expression levels in MDA‐MB‐231 cells. Abstract Breast cancer is one of the most prevalent malignancies among women worldwide.
Fateme Nikakhtar   +2 more
wiley   +1 more source

Protein Corona Engineering of Lipid Nanoparticles Enables Efficient Functional Gene Silencing in the Liver

open access: yesSmall, EarlyView.
By shaping the protein corona, lipid composition directs LNP tropism and enables the preferential delivery of a TIMP1‐targeting siRNA to liver macrophages. In a murine model of primary biliary cholangitis, this strategy promoted macrophage reprogramming and attenuated liver fibrosis.
Naths G. Sukubo   +15 more
wiley   +1 more source

Cancer symptom cluster in hospitalized women with breast cancer: a descriptive observational study. [PDF]

open access: yesRev Bras Enferm
Silva RJG   +6 more
europepmc   +1 more source

HER2‐Targeted AIE Nanotheranostics Overcome SHR‐A1811 Resistance via Immunogenic Pyroptosis and Tumor‐Associated Macrophage Reprogramming in Breast Cancer

open access: yesSmall, EarlyView.
HER2‐targeted AIE780‐A1811 nanoparticles self‐assemble via amide coupling of a mitochondria‐directed photosensitizer with the ADC SHR‐A1811. Upon 660 nm irradiation, they generate ROS, photothermal effects, and controlled drug release, inducing immunogenic pyroptosis and M2‐to‐M1 macrophage reprogramming. This dual action remodels the immunosuppressive
Xiaohong Liu   +12 more
wiley   +1 more source

Alkyl chain elongation engineering: Unlocking high‐brightness NIR‐II O‐xanthene dyes for in vivo bioimaging

open access: yesSmart Molecules, EarlyView.
O‐xanthene–based fluorophore enhanced fluorescence quantum yield and brightness were achieved by extending the N‐alkyl chain on the aniline donor. Abstract NIR‐II fluorescent probes are powerful tools for advanced imaging, with performance governed by molar extinction coefficient (ε), quantum yield (Φ), and brightness (ε × Φ).
Yu Zhao   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy