Results 21 to 30 of about 4,657 (141)

Las células dendríticas plasmacitoides evocan la respuesta efectora de los linfocitos T citotóxicos específicos para Salmonella.

Biomédica: revista del Instituto Nacional de Salud, 2019
Introducción. La función inmunológica de las células dendríticas plasmacitoides durante las infecciones bacterianas, como la de Salmonella spp., es poco conocida.
Carolina del Carmen Murúa-López, María González-Orozco, Héctor Samuel López-Moreno   +2 more
doaj   +1 more source

New Approach Methodologies (NAMs) in Alternative Methods: A Comparative Cytotoxicity Analysis of Nanostructured Hydroxyapatite in Adipose Stem Cells Spheroids

Journal of Applied Toxicology, EarlyView.
ABSTRACT Toxicological assessment is essential in NP approval for health and medical applications. Although 2D cell culture has been widely used, 3D models, especially spheroids, provide better predictive value for toxicological risk assessments since they replicate complex cellular interactions more accurately.
Bianca Montenegro, Rosângela Mayer Gonçalves, Marcelle Gomes Pegurier, Isabelle Amorim, Alexandre Malta Rossi, Leandra Santos Baptista   +5 more
wiley   +1 more source

INOVAÇÕES E DESAFIOS NA TERAPIA COM CÉLULAS CAR-T: DA MODELAGEM EM LEUCEMIA CRÔNICA À SINERGIA COM CÉLULAS NK

Hematology, Transfusion and Cell Therapy
Introdução: A terapia CAR-T usa células T do próprio paciente modificadas geneticamente para combater o câncer. Estudos mostram que a CAR-T direcionada ao CD19 é eficaz contra leucemias, especialmente a leucemia linfoblástica aguda recidivante/refratária.
GS Correa, SZ Jorge, HC Silva, AC Ramalho, MBC Silveira, LFT Ribeiro, MEJ Marinho, RVP Souza, PHSCD Santos, G Suhett   +9 more
doaj   +1 more source

Candidozyma cisalpinoae sp. nov., a Genomically Distinct, Flower‐Associated Yeast, Resistant to Azoles and Exhibiting Pathogenicity‐Related Traits

Yeast, EarlyView.
Candidozyma cisalpinoae sp. nov. represents a distinct species within the Candidozyma clade, supported by multilocus phylogeny, genome‐scale metrics, and phenotypic traits. Although isolated from floral substrates, this species displays several traits commonly associated with opportunistic pathogenic yeasts.
Anna Paula O. Tironi, Katharina O. Barros, Luiz Felipe A. Santana, Daniela L. Souza, Ana Raquel O. Santos, Giovana R. Ávila, Thiago M. Batista, Glória R. Franco, Raphael S. Pimenta, Paula B. Morais, Marc‐André Lachance, Carlos A. Rosa, Susana Johann   +12 more
wiley   +1 more source

Cellular Morphometric Analysis (CellMorph)—a comprehensive imaging‐based tool for quantifying cellular phenotype heterogeneity and dynamics across biological processes

The FEBS Journal, EarlyView.
CellMorph is a groundbreaking tool that allows researchers to analyze multiple features from single cells, including cell size and shape, cytosolic staining and subcellular texture, nuclear staining, and morphometry. By evaluating images from both bright‐field and fluorescence microscopy, it also tracks changes in living cells during key processes such
Henrique Quaiato de Oliveira, Solon Andrades da Rosa, Luiza Cherobini Pereira, Laura Boose de Mendonça, Juliete Scholl, Fabrício Figueiró, Thais Cardoso Bitencourt, Davi Piovesan Echevarria, João Luiz Aldinucci Buzzo, Jessica Boschini D'Agostin, Danieli Rosane Dallemole, Carolina Oliveira, Fernanda Simas, Fernanda Saez‐Calazans, Débora Santos‐Sousa, Guido Lenz, Eduardo C. Filippi‐Chiela   +16 more
wiley   +1 more source

Fotoferese extracorpórea Extracorporeal photopheresis

Revista Brasileira de Hematologia e Hemoterapia, 2008
Fotoferese extracorpórea é uma modalidade de terapia celular que tem demonstrado eficácia e segurança em pacientes portadores de doenças auto-imunes e mediadas por células T, incluindo esclerodermia, linfoma de células T cutâneo/ Síndrome de Sézary e ...
Márcia M. Silva, Luis Fernando S. Bouzas   +1 more
doaj   +1 more source

Assessing D‐Squame as a Minimally Invasive Technique to Evaluate the Cutaneous Immune Response mRNA in a Dog Model of Canine Atopic Dermatitis

Veterinary Dermatology, EarlyView.
ABSTRACT Background Canine atopic dermatitis (cAD) is a multifactorial, inherited skin disease, estimated to affect ≤ 15% of dogs. Studies of skin messenger mRNA in cAD currently use invasive methods, including blood sampling and biopsy collection, whilst advances in human atopic dermatitis study methodology have demonstrated reliable use of minimally ...
Xavier Langon, Marion Mosca, Nadège Milhau, Mélanie Legain, Adrien Idée, Didier Pin   +5 more
wiley   +1 more source

Inhibition of caspase-8 activity reduces IFN-gamma expression by T cells from Leishmania major infection

Anais da Academia Brasileira de Ciências, 2008
Following infection with Leishmania major, T cell activation and apoptosis can be detected in draining lymph nodes of C57BL/6-infected mice. We investigated the mechanisms involved in apoptosis and cytokine expression following Tcellactivation. After two
Wânia F. Pereira, Landi V.C. Guillermo, Flávia L. Ribeiro-Gomes, Marcela F. Lopes   +3 more
doaj   +1 more source

Bacteriophage and Fusidic Acid Have Synergistic Effect Against Meticillin‐Resistant Staphylococcus pseudintermedius in Ex Vivo Canine Dermis Model

Veterinary Dermatology, Volume 37, Issue 2, Page 200-210, April 2026.
Background: Antimicrobial stewardship has become vital given the progressive emergence of multidrug‐resistant bacteria, and novel approaches to the treatment of bacterial infections are needed. Recently, reported synergistic effects of antibacterial drugs and bacteriophage therapy have revealed promising applications for the management of meticillin ...
Sarah Ehling, Elisa Peh, Hilke Oltmanns, Jessica Meissner, Sophie Kittler, Christina Puff, Jutta Verspohl, Mathias Müsken, Madeleine Plötz, Andrea Vanessa Volk   +9 more
wiley   +1 more source

RELATO DE TRÊS CASOS DE SÍNDROME DE SÉZARY COM EXPRESSÃO ABERRANTE DO CD200

Hematology, Transfusion and Cell Therapy, 2023
Objetivo: CD200 é um marcador celular empregado no diagnóstico de neoplasias linfoproliferativas de células B maduras (DLPC-B), sendo comumente usado nos painéis de triagem para avaliação de células B do sangue periférico nas doenças linfoproliferativas ...
MDGP Araújo, IAF Bahia, RD Lima, RE Martins, FCM Theodoro, RDA Soares, LKF Silva, EC Bezerra, GHM Oliveira, GBC Junior   +9 more
doaj   +1 more source