Results 61 to 70 of about 808,601 (248)

The relationship of E-cadherin with colorectal adenocarcinoma prognosis [PDF]

open access: yes, 2005
BACKGROUND: To evaluate the relationship between E-cadherin and recurrence, relapse free survival, overall survival and TNM system in patients operated on for colorectal adenocarcinoma.
Artigiani Neto, Ricardo   +3 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

A thousand total colonoscopies: what is the relationship between distal and proximal findings? [PDF]

open access: yes, 2008
BACKGROUND: Flexible sigmoidoscopy is indicated for colorectal cancer screening. The decision about who needs total colonoscopy based on distal findings is still controversial because of the uncertainty of the associations between distal and proximal ...
Andrade, CS   +5 more
core  

A metoclopramida prejudica a cicatrização de anastomoses do cólon esquerdo de ratos? [PDF]

open access: yes, 2011
Objetivo: Avaliar os efeitos da metoclopramida sobre a formação de aderências e a cicatrização de anastomoses de cólon esquerdo de ratos. Métodos: 40 ratos distribuídos em dois grupos contendo 20 animais, para administração de metoclopramida (grupo ...
Feres, Omar   +4 more
core   +3 more sources

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Alimentos funcionais: conceitos básicos. [PDF]

open access: yes, 2019
bitstream/item/44301/1/documento-312 ...
KROLOW, A. C. R.   +2 more
core   +1 more source

El impacto del SAS 82-Consideraciones de fraude en la auditoría de estados financieros- en la práctica de la contabilidad pública de firmas locales y practicantes independientes en Puerto Rico

open access: yesFórum Empresarial, 1999
Sinopsis de las siguientes tesis: El impacto del SAS 82-Consideraciones de fraude en la auditoría de estados financieros- en la práctica de la contabilidad pública de firmas locales y practicantes independientes en Puerto Rico, Análisis financiero ...
Glorimar Pérez Colón
doaj   +1 more source

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