Results 61 to 70 of about 805,425 (200)
Creating a Patient-Centric, Global, Decentralized Health System
Session Description: Over the past decade, there have been many innovations in new payment and care delivery models and technology – from telemedicine to AI to blockchain. These innovations, however, need to be used in tandem to drive real change.
Kenneth Colon
doaj
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Câncer de cólon e estresse oxidativo
O câncer de cólon e reto foi o terceiro mais incidente entre a população feminina e o quarto mais incidente entre os homens da região Sudeste do Brasil em 2008. Assim como nas demais patologias que afetam o trato gastrintestinal, essa neoplasia debilita
Eloi Francisco Rosa +1 more
doaj
Minilaparotomias para tratamento de doenças do cólon
OBJETIVO: Estudar as possibilidades técnicas e resultados obtidos com pequenas incisões para tratar doenças do cólon. MÉTODO: Vinte e seis pacientes, 12 do sexo masculino e 14 do feminino foram submetidos a laparotomias com incisões menores que 10cm.
Peretz Capelhuchnik +4 more
doaj +1 more source
Este artículo examina algunas de las posturas defendidas por un grupo de mujeres negras y mulatas en la revista Minerva: revista quincenal dedicada a la mujer de color, en el ocaso del siglo XIX cubano.
Maikel Colón Pichardo
doaj +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
El propósito de esta investigación cuantitativa correlacional fue determinar cómo se relaciona el estilo de liderazgo del director escolar con la motivación laboral de los empleados de la Generación Millennials.
Melissa Hernández Colón
doaj
Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki +6 more
wiley +1 more source

