Results 51 to 60 of about 126,902 (239)

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

Advanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis, Luis Carlos Sanjuan Acosta, Shubh P. Mehta, Baiyan Qi, Yang Yang, Luis Solorio, Craig J. Goergen, David J. Cappelleri   +7 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Investigações sobre a sensibilidade da córnea em animais [PDF]

, 2013
Resumo: A inervação da córnea é suprida por neurônios sensoriais originários do gânglio do nervo trigêmio, sendo estas terminações nervosas sensíveis a uma variedade de estímulos externos e denominados nociceptores polimodais.
Cantarella, Raquel de Araujo
core   +1 more source

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

Advanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen, Yan Yang, Haihan Gao, Yan Liu, Xinyue Wang, Linghao Song, Ruohong Li, Ao Miao, Jie Xu, Zhennan Zhao, Dan Li, Shenjie Peng, Linzhao Li, Min Zhang, Yonghang Liu, Liren Wang, Tianhui Chen, Yongxiang Jiang   +17 more
wiley   +1 more source

Uso do plasma rico em plaquetas no reparo de úlceras de córnea profundas induzidas em coelhos. Avaliação clínica e histomorfométrica

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2013
Avaliou-se e comparou-se, clinicamente, por meio de histopatologia e morfometria, o processo de reparação corneana de úlceras experimentais induzidas em coelhos, com o uso de plasma rico em plaquetas (PRP) sob a forma de colírio ou tampão.
C. Donatti, C.V.S. Brandão, J.J.T. Ranzani, C.S. Perches, C.R. Padovani, C.H. Pellizzon, M.G. Sereno   +6 more
doaj   +1 more source

Una producción córnea extraordinaria : Cuerno cutáneo [PDF]

, 2022
A fines del año próximo pasado, llegó al mercado de lanares, ubicado en la estación Tablada, procedente de una estancia del partido de General Pintos, la oveja cuya fotografía se reproduce y que presentaba un enorme cuerno cutáneo en la parte media de la
Reibel, Jorge
core  

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Meibografía. Nueva tecnología para la evaluación de las glándulas de Meibomio

Revista Mexicana de Oftalmología, 2017
La meibografía es una tecnología que nos permite evaluar la morfología de las glándulas de Meibomio in vivo de una forma no invasiva y con pocas o nulas molestias.
Manuel Garza-Leon, Nallely Ramos-Betancourt, Francisco Beltrán-Diaz de la Vega, Everardo Hernández-Quintela   +3 more
doaj   +1 more source

A Plant Photoregulator‐Inspired S‐Type Heterojunction System for Diabetic Keratopathy via Tri‐Modal Light‐Driven Immunometabolic Reprogramming, Tissue Repair, and Antibacterial Activity

Advanced Science, EarlyView.
To address the multifaceted imbalance in diabetic keratopathy, a light‐responsive biomimetic platform (WCNx‐Rh2) is developed and integrates glucose degradation, immune modulation, and antibacterial defense through a designed heterojunction and screened immunomodulator. WCNx‐Rh2 reduces AGEs/ROS and inflammatory signaling, reprogramming dendritic cells
Mengzhen Zhao, Zhibin Zhou, Yuxuan Wei, Xiangfan Huang, Zhiyong Zhou, Jiaheng Chen, Haoxin Cheng, Xiaotian Hu, Xiaolei Wang   +8 more
wiley   +1 more source

Trasplante de córnea: retos y perspectivas

Universidad Médica Pinareña, 2014
Introducción: los trasplantes de órganos son reconocidos a nivel internacional como la opción terapéutica por excelencia para los pacientes con enfermedades crónicas degenerativas y constituyen el único tratamiento capaz de rehabilitarlos integralmente y
Martínez Noda Sandra María, Jorge Ernesto Oliva Santos, Omar Javier Melian Balestena, Eduardo Rojas Álvarez   +3 more
doaj   +2 more sources