Results 61 to 70 of about 99 (98)
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi +13 more
wiley +1 more source
A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione +2 more
wiley +1 more source
This study evaluated four stereotactic radiosurgery planning approaches for posterior choroidal melanoma (CM). Analysis of thirteen CM cases resulted in a clinically meaningful reduction in dose to the brain for Brainlab Elements modulated arcs (BE) and Varian Eclipse HyperArc modulated arcs (HA) compared to Brainlab iPlan dynamic conformal arc therapy
Robert Nigro +5 more
wiley +1 more source
The utility of whole exome sequencing in diagnosing Wilson disease: A case report
Abstract Wilson disease (WD) is an autosomal recessive disorder of copper metabolism caused by mutations in the ATP7B gene, resulting in toxic copper accumulation in the body. Diagnosis is typically based on biochemistries, including low serum ceruloplasmin and elevated 24‐h urine copper excretion, with Kayser–Fleischer (KF) rings being a supportive ...
Mihir J. Palan +4 more
wiley +1 more source
Microbial communities and functional diversity in seafood
Abstract Functional diversity encompasses ecosystem processes that enhance adaptability to environmental change. This study explores the diversity of microorganisms associated with seafood. In this paper, we present our knowledge of microbial diversity in relation to seafood.
Christian Larbi Ayisi +3 more
wiley +1 more source
A Novel Slit Lamp‐Based System for 3D Ultrasound of the Eye
Objectives This study aims to develop and evaluate a novel slit‐lamp‐based system to acquire 3‐dimensional (3D) ultrasound volumes using conventional ultrasound probes. Methods A slit‐lamp adapter was 3D printed and connected with a linear actuator and graphical user interface (GUI) system to control movement and create volumes of 2‐dimensional scans ...
Claire E. Malley +9 more
wiley +1 more source
ABSTRACT Following anterior cruciate ligament (ACL) reconstruction, enhancing hamstring tenocyte activity and minimizing apoptosis are critical for preventing graft failure and promoting ligamentization. This study investigated the therapeutic potential of extracellular vesicles (EVs) derived from a coculture of ACL remnant cells and bone marrow ...
Hon‐Lok Lo +5 more
wiley +1 more source
ABSTRACT Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...
Fei Xu +4 more
wiley +1 more source
This systematic review and meta‐analysis of 53 studies and 1354 patients evaluates the outcomes of temporalis muscle transfer in facial nerve paralysis. Our results show that temporalis muscle transfer can restore smile asymmetry, oral commissure movement, and eyelid closure—findings that are translated to clinician‐rated assessments.
Amirpouyan Namavarian +7 more
wiley +1 more source
Nile Red‐loaded poly(solketal acrylate) nanoparticles enable fluorescence tracking and exhibit nontoxic profiles in retinal cells. Enhanced cellular uptake and deep retinal penetration after intravitreal injection highlight their excellent potential for targeted ocular drug delivery to the posterior segment of the eye.
Yasaman Pourdakheli Hamedani +6 more
wiley +1 more source

