Results 111 to 120 of about 748,226 (258)
Pyridine-Catalyzed Double C–N Coupling Reaction of an Isocyanate with Two Benzynes
, 2011 A pyridine-catalyzed double C–N bond cross-coupling reaction involving two benzynes with an isocyanate was carried out. The coupling reaction proceeded through a unique pathway involving the formation of an unstable carbamic acid intermediate and facile ...
Yi-Hsien Lee +4 more
core +1 more source
Photoinduced C-C Cross-Coupling of Aryl Chlorides and Inert Arenes
International Journal of Photoenergy, 2016 Here we report a facile, efficient, and catalyst-free method to realize C-C cross-coupling of aryl chlorides and inert arenes under UV light irradiation.
Lele Wang +3 more
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
(In-)stability and stabilisation of QNL-type atomistic-to-continuum coupling methods [PDF]
, 2014 We study the stability of ghost force-free energy-based atomistic-to-continuum coupling methods. In 1D we essentially complete the theory by introducing a universally stable a/c coupling as well as a stabilisation mechanism for unstable coupling schemes.
A. V. Shapeev +5 more
core +1 more source
Cross-coupling polycondensation via C–O or C–N bond cleavage
Nature Communications, 2018 π-Conjugated polymers are useful commodities as they are used in the fabrication of organic photovoltaic devices, light-emitting diodes and field effect transistors.
Ze-Kun Yang +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
, 2019 Unstrained cyclic ketones can participate in cooperative Suzuki-Miyaura cross-coupling type reaction using rhodium(I)-based catalyst via C-C bond activation.
Lili, Zhao +2 more
core +1 more source
Palladium(0) Deposited on PAMAM Dendrimers as a Catalyst for C–C Cross Coupling Reactions
Molecules, 2011 PAMAM dendrimers of generations G2–G3 as well as a partially substituted derivative of generation G4 and a low-molecular-weight tricyclic ligand 4 were used to bind Pd(0) nanoparticles. The obtained adducts were tested as catalysts for C–C cross-coupling
Tomasz Borkowski +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Introducing alkyl groups, particularly through innovative C(sp2)-C(sp3) bond-forming methods utilizing abundant feedstocks, holds promise for expanding chemical diversity, especially in drug discovery programs.
Biplab, Maji +4 more
core +1 more source