Results 21 to 30 of about 11,319 (119)

Spatiotemporally Adaptive Bilayer Silk Fibroin–Polyvinyl Alcohol–Metformin Composite Coating on Biodegradable Zinc for Orthopedic Applications

open access: yesRare Metals, Volume 45, Issue 7, July 2026.
ABSTRACT Biodegradable zinc (Zn)‐based materials are considered promising candidates for orthopedic applications because of their favorable mechanical properties, controllable biodegradability, and good biosafety profiles. However, their clinical translation is limited by early‐stage corrosion‐induced cytotoxicity and inflammation, as well as ...
Jinlong Mao   +9 more
wiley   +1 more source

Land use overrides climatic controls on soil organic nitrogen transformations: Contrasting responsiveness between forest and cropland ecosystems

open access: yesFunctional Ecology, Volume 40, Issue 7, Page 2128-2142, July 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Soil organic nitrogen (SON) transformation is critical for global nutrient cycling and ecosystem productivity, yet how its responsiveness to climate change differs across diverse land use types remains poorly resolved.
Xinyi Yang   +10 more
wiley   +1 more source

3D Printed High‐Strength Hydrogel for Dual Release of Cu2+ and Ag+ Ions to Enhance Bone Repair and Antibacterial Properties

open access: yesRare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT Bone restoration is often hindered by the spatiotemporal dysregulation of immune and regenerative signals. Conventional bio‐inert implants, providing only passive support, fail to modulate this microenvironment, leading to infections and poor healing.
Zhizhong Sun   +8 more
wiley   +1 more source

Efficacy of Der f 2/Zen 1‐LAMP1 Plasmid‐Based Vaccine Immunotherapy in Dogs With Atopic Dermatitis: A Proof‐of‐Concept Study

open access: yesVeterinary Dermatology, Volume 37, Issue 2, Page 306-318, April 2026.
Background: DNA‐based vaccination rapidly induces strong cellular and humoral immune responses, which may be enhanced by inclusion of lysosomal‐associated membrane protein‐1 (LAMP). Objectives: This proof‐of‐concept study evaluated the efficacy and safety of a Der f 2/Zen 1‐LAMP‐based DNA vaccine immunotherapy in client‐owned dogs with nonseasonal AD ...
Petra Bizikova   +6 more
wiley   +1 more source

C-反应蛋白定量检查在小儿急性呼吸道感染中的诊断价值

open access: yesZhongguo shiyan zhenduanxue, 2014
C反应蛋白属于急性时相反应蛋白,是炎症反应的标志性蛋白。在正常健康人体内的C反应蛋白水平较低,当机体组织发生感染或者组织损伤后,其水平在6-8h后开始升高,在24-48h内水平达到最高[1-4]。本文选择我院急性呼吸道感染患儿,观察C反应蛋白水平检测在此类患儿中的临床意义,现报告如下。1资料和方法1.1一般资料所选急性呼吸道感染患儿共62例 ...
何书香
doaj  

Nutritional and Physiological Markers Are Mediated by Seasonality and Forest Access in Captive Coquerel's Sifakas 圈养科氏冕狐猴 (Coquerel's Sifakas) 的营养和生理指标受季节性和森林通道的影响

open access: yesIntegrative Conservation, Volume 4, Issue 4, Page 652-664, December 2025.
We profiled nutritional and physiological markers in captive sifakas, endangered primates from Madagascar, managed in expansive, non‐native forest enclosures. Variation in many markers reflects freely foraged diets and the energy required to maintain homeostasis under more naturalistic conditions.
Lydia K. Greene   +5 more
wiley   +1 more source

妊娠期糖尿病患者脂联素及C-反应蛋白水平的临床研究

open access: yesZhongguo shiyan zhenduanxue, 2012
目的探讨妊娠期糖尿病患者早、中孕期的脂联素及C-反应蛋白水平的相关性。为早期预测妊娠期糖尿病提供科学依据。方法选于10-14周已在我院确诊妊娠并产检孕妇,所有孕妇于孕10-14周进行常规体检测身高、体重、血压、血浆脂联素、C-反应蛋白、空腹血糖、孕24-28周复查血浆脂联素、C-反应蛋白、OGTT葡萄糖耐量试验及胰岛素,计算胰岛素抵抗指数,跟踪孕妇至妊娠分娩,根据糖耐量结果分为妊娠期糖尿病组与正常妊娠妇女组对照。对照妊娠期糖尿病孕早、中期血浆脂联素、C-反应蛋白水平及其他检验指标。结果 GDM组10 ...
芦雅苹   +4 more
doaj  

Evaluation of filaggrin 2 expression in dogs with atopic dermatitis before and after oclacitinib maleate administration

open access: yesVeterinary Dermatology, Volume 36, Issue 4, Page 453-461, August 2025.
Background – Canine atopic dermatitis (cAD) is a chronic, inflammatory, multifactorial and pruritic disease. The presence of skin barrier impairment (e.g. filaggrin alterations), along with abnormal immune responses, can negatively impact cutaneous barrier function.
Wendie Roldan Villalobos   +5 more
wiley   +1 more source

2型糖尿病视网膜病变与C-反应蛋白及代谢综合征关系的研究

open access: yesZhongguo shiyan zhenduanxue, 2014
有研究表明,C-反应蛋白、血脂参与了糖尿病病人血管病变的发生、发展。因此检测糖尿病病人血清中的C-反应蛋白、血脂水平对于糖尿病病人血管病变的早期诊断、病情分析以及预后评价具有非常重要的临床价值。但是目前国内外对于C-反应蛋白、代谢综合征(metabolic syndrome,MS)与糖尿病视网膜病变发生和预测之间关系的研究还比较少[1,2],本研究初步探讨C ...
吴雪梅
doaj  

Long‐lasting otic solution containing mometasone furoate can influence intradermal testing in dogs with healthy ears and otitis externa

open access: yesVeterinary Dermatology, Volume 35, Issue 6, Page 736-744, December 2024.
Background – Topical therapy is preferred for otitis externa (OE) in dogs, and otic products commonly contain glucocorticoids that can be systemically absorbed and possibly interfere with diagnostic tests such as intradermal testing (IDT). Hypothesis/Objectives – To determine the effect of a long‐lasting otic solution containing mometasone furoate (MF)
Jennifer L. Clegg   +2 more
wiley   +1 more source

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