Highlights A significant upregulation of glucokinase (GCK) expression was found in type 2 diabetes (T2D) subjects with adequate glucose control, but such increase was undetected in T2D with poor glycemic control. A strong positive correlation between GCK levels and spliced X‐box binding protein 1 (XBP1s)/activating transcription factor 4 (ATF4 ...
Jingwen Liu +6 more
wiley +1 more source
Meta-analysis of effects of long-term exposure to PM2.5 on C-reactive protein levels [PDF]
BackgroundFine particulate matter (PM2.5) is a serious air pollutant associated with elevated levels of C-reactive protein (CRP), an inflammatory indicator.ObjectiveTo assess the potential impacts of long-term exposure to PM2.5 on CRP levels based on ...
Haiming XU +5 more
core +2 more sources
Highlights This study is the first registered meta‐analysis with three different insights to explore the relationship between the glycated hemoglobin (HbA1c) variability and the risk of cardiovascular disease (CVD). Our study suggests that the higher glucose fluctuation is significantly associated with the higher CVD risk in diabetes patients based on ...
Feng Li +6 more
wiley +1 more source
Canine dermatitis on contacting grass leaf: A case series
Background – Pruritus is a common clinical sign in dogs for which owners seek veterinary attention. Its diagnosis and treatment can be a source of frustration for the owner and veterinarian alike. A contact dermatitis is considered rarely, even when lesions are located only on the skin.
Kenneth Mason, Merja Ruutu
wiley +1 more source
The Association of Retinal age gap with metabolic syndrome and inflammation 视网膜年龄差与代谢综合征和炎症的关系
Highlights Retinal age gap is a non‐invasive and cost‐effective aging biomarker. Retinal age gap was significantly associated with metabolic syndrome and inflammation. Retinal age gap could be potentially used as a screening tool for metabolic syndrome in large populations.
Zhuoting Zhu +13 more
wiley +1 more source
Correlation of Malnutrition,25-hydroxy Vitamin D and Interleukin-1β with Chronic Obstructive Pulmonary Disease in Elderly Inpatients [PDF]
BackgroundThe specific pathogenesis of chronic obstructive pulmonary disease (COPD) is still not very clear so far, clinical interventions mainly focus on the control of pulmonary symptoms with drugs, however, the influence of extrapulmonary related ...
DAI Jingrong, LI Jie, HE Xu, LI Yang, LI Yan
core +1 more source
ANCA相关性血管炎的诊治和疗效评估指标研究近况 [PDF]
抗中性粒细胞胞浆抗体(antineutrophil cytoplasmic autoantibody,ANCA)相关性血管炎(ANCA associated vasculiltis,AAV)是一组自身免疫性系统性疾病,其病理特征为小血管壁的炎症和纤维素样坏死,中、老年人多见,累及肾脏即为ANCA相关性肾小球肾炎(AAGN),免疫抑制剂为主要治疗药物,易导致严重感染等副作用,故须准确判断疾病的活动性和病情变化来决定治疗方案及疗程。现就目前研究评估疾病活动及疗效的指标如伯明翰血管炎活动度计分、肾脏病理类型 ...
彭卫华, 许敏敏, 陈凌舟
core +1 more source
血小板/淋巴细胞比值在慢性阻塞性肺病急性加重早期诊断中的应用价值
目的 评估血小板/淋巴细胞比值在慢性阻塞性肺病急性加重早期诊断中的应用价值。方法 回顾性研究南京医科大学附属苏州医院呼吸与危重症医学科2019年3月至2021年6月住院治疗151例慢性阻塞性肺病患者的一般临床资料。分为AECOPD组(急性加重组)和SCOPD组(稳定期组),比较两组患者的一般临床资料、PLR、降钙素原、C反应蛋白等的差异。通过受试者操作特征(ROC)曲线下的面积(AUC)评估PLR及相关危险因素在慢性阻塞性肺病急性加重早期诊断中的临床价值。结果 ACCOPD组患者年龄、吸烟比例 ...
徐靖宇 +4 more
doaj
Effect of Acupuncture as an Adjuvant Therapy for Intravenous Thrombolytic Treatment on Peripheral Inflammatory Factors and Neurologic Function in Patients with Acute Ischemic Stroke [PDF]
BackgroundAcupuncture has proved effective in reducing inflammatory cytokine levels. However, it is still unclear about its improvement on the neurologic function and activities of daily living as well as over all clinical efficacy in patients with acute
CHEN An, CAO Xiao, ZHANG Huilin, LIAN Jianfeng
core +1 more source
Study on the Relationship between Blood Stasis Syndrome and HOMA-IR, Hs-CRP and NIHSS Score of Acute Cerebral Infarction [PDF]
摘要 目的:比较急性脑梗死血瘀证与非血瘀证之间胰岛素抵抗、超敏C反应蛋白、NIHSS评分和血脂四项等指标是否有差异性,探讨急性脑梗死血瘀证与胰岛素抵抗、炎症因子及神经功能缺损程度的关系,从而提高对急性脑梗死血瘀证的认识,为临床应用活血化瘀法治疗脑梗死提供理论依据。 方法:选取厦门市中医院脑病科2013年12月至2014年12月期间内明确诊断急性脑梗死的住院患者,按照病例纳入标准选取血瘀证组和非血瘀证组病例各40例,两组分别检测空腹血糖,空腹血清胰岛素,Hs-CRP、血脂四项等相关生化指标 ...
罗艾君
core

