Results 81 to 90 of about 10,732,131 (260)

Advanced artificial intelligence in piRNA and PIWI-like protein research: A systematic review of recurrent neural networks, long short-term memory, and emerging computational techniques

open access: yesBiomédica: revista del Instituto Nacional de Salud
Introduction. PIWI-interacting RNAs are small and non-coding RNAs involved in gene regulation and transposable element repression, emerging as critical biomarkers and therapeutic targets in oncology. Advances in artificial intelligence, such as recurrent
Jheremy Sebastián Reyes   +6 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Effects of nozzle design on the noise from supersonic jets [PDF]

open access: yes
The aeroacoustic supersonic performance of various internal nozzle geometries is evaluated for shock noise content over a wide range of nozzle pressure ratios.
Maestrello, L.   +2 more
core   +1 more source

Voces actuales en el fenómeno de pasantes de drogas ilícitas en Colombia

open access: yesRevista Criminalidad, 2017
Este documento se deriva del análisis realizado a las narrativas de los pasantes de drogas ilícitas denominados popularmente como “mulas”; de manera especial, resalta su mirada localizada sobre el fenómeno del tráfi co ilegal de drogas en Colombia.
Galia J. Benítez   +5 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Trabajo en casa y calidad de vida: una aproximación conceptual [PDF]

open access: yesCuadernos Hispanoamericanos de Psicología, 2014
Teleworking means working at home. This type of work is not new and it is under rulemaking process in Colombia. As it is a widespread work modality, its impact on health and quality of life must be determined.
Yolanda Sierra Castellanos   +2 more
doaj  

Análisis sobre la conducta criminal de violadores seriales en casos ocurridos en Bogotá, D. C. (2008-2012)

open access: yesRevista Criminalidad, 2014
Introducción: en la actualidad, la constante victimización de personas por delitos sexuales es uno de los fenómenos que más afectan a la comunidad, la cual, pese al apoyo de las áreas clínica, jurídica y social, entre otras (Meng & Thomas, 2010; ICBF ...
Deimer Meléndez-Cardona   +2 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Análisis descriptivo de contenidos y registros administrativos de la Revista Criminalidad, 2008-2016

open access: yesRevista Criminalidad, 2018
Introducción: por haber cumplido 60 años de publicación de la Revista Criminalidad, se realizó un análisis de sus contenidos en el periodo del 2008 al 2016, el espacio de tiempo durante el cual se prestó atención a la adopción de los parámetros de las ...
Juan Aparicio Barrera   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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